Phase II study of induction and adjuvant chemotherapy for squamous cell carcinoma of the head and neck: A long term analysis for the Illinois Cancer Center

Cancer

Volumn 79, Issue 3, 1997, Pages 588-594

  Athanasiadis, Ilias ^a   Taylor IV, Samuel ^b   Vokes, Everett E ^c   Pelzer, Harold J ^a   Rademaker, Alfred ^a   Mittal, Bharat B ^a   Ganzenko, Natalia ^a   Blough, Richard ^a   Lester, Eric P ^c   Kies, Merrill S ^a,d  

^a NORTHWESTERN UNIVERSITY   (United States)

^b ADVOCATE ILLINOIS MASONIC MEDICAL CENTER   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d NW Univ Feinberg School of Medicine   (United States)

Author keywords

5 fluorouracil; chemotherapy; cisplatin; head and neck; squamous cell carcinoma

Indexed keywords

CISPLATIN; FLUOROURACIL;

ADULT; AGED; ARTICLE; BONE MARROW SUPPRESSION; CANCER ADJUVANT THERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; CLINICAL TRIAL; FEMALE; HEAD AND NECK CARCINOMA; HUMAN; HYPOTHYROIDISM; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MALE; MUCOSA INFLAMMATION; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; QUALITY OF LIFE; SECOND CANCER; TREATMENT OUTCOME; XEROSTOMIA;

ADULT; AGED; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SQUAMOUS CELL; CHEMOTHERAPY, ADJUVANT; CISPLATIN; DISEASE-FREE SURVIVAL; FEMALE; FLUOROURACIL; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MIDDLE AGED; REMISSION INDUCTION; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 0031023958     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0142(19970201)79:3<588::AID-CNCR23>3.0.CO;2-Z     Document Type: Article

References (15)

1. Vokes EE, Weichselbaum RR, Lippman S, Hong WK. Head and neck cancer. N Engl J Med 1993;328:184-94.
2. Kish JA, Weaver A, Jacobs J, Cummings G, Al-Sarraf M. Cisplatin and 5-fluorouracil infusion in patients with recurrent and disseminated epidermoid cancer of the head and neck. Cancer 1984;53:1819-24.
3. Lo TC, Wiley AL Jr., Ansfield FJ, Brandenburg TH, Davis HL Jr., Gollin FF, et al. Combined radiation therapy and 5-fluorouracil for advanced squamous cell carcinoma of the oral cavity and oropharynx: a randomized study. AJR Am J Roentgenol 1976;126:229-35.
4. Merlano M, Vitale V, Rosso R, Benasso M, Corvo R, Cavallari M, et al. Treatment of advanced squamous cell carcinoma of the head and neck with alternating chemotherapy and radiotherapy. N Engl J Med 1992;327:1115-21.
5. Head and Neck Contracts Program. Adjuvant chemotherapy for advanced head and neck squamous carcinoma: final report Cancer 1987;60:301-11.
6. Schuller DE, Metch B, Stein DW, Mattox D, McCracken JD. Preoperative chemotherapy in advanced resectable head and neck cancer: final report of the Southwest Oncology Group. Laryngoscope 1988;98:1205-11.
7. The Department of Veterans Affairs Laryngeal Cancer Study Group. Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. N Engl J Med 1991;324:1685-90.
8. Laramore GE, Scott CB, Al-Sarraf M, Haselow RE, Ervin TJ, Wheeler R, et al. Adjuvant chemotherapy for resectable squamous cell carcinoma of the head and neck: report on Intergroup study. Int J Radiat Oncol Biol Phys 1992;23:705-13.
9. Paccagnella A, Orlando A, Marchiori C, Zorat PL, Cavaniglia G, Sileni VC, et al. Phase III trial of initial chemotherapy in stage III or IV head and neck cancers: a study by the Gruppo di Studio sui Tumori della Testa e del Collo. J Natl Cancer Inst 1994;86:265-72.
10. Ervin TJ, Clark JR, Weichelbaum RR, Fallon BG, Miller D, Fabian RL. An analysis of induction and adjuvant chemotherapy in the multidisciplinary treatment of squamous cell carcinoma of the head and neck. J Clin Oncol 1987; 5:10-20.
11. Jacobs C, Makuch R. Efficacy of adjuvant chemotherapy for patients with resectable head and neck cancer: a subset analysis of the Head and Neck Contracts Program. J Clin Oncol 1990;8:838-47.
12. Vokes EE, Ratain MJ, Mick R, McEvilly JM, Haraf D, Kozloff M, et al. Cisplatin, fluorouracil and leukovorin augmented by interferon alpha-2B in head and neck cancer: a clinical and pharmacologic analysis. J Clin Oncol 1993;11:360-8.
13. Vokes EE, Kies M, Haraf DJ, Mick R, Moran WJ, Kozloff M, et al. Induction chemotherapy followed by concomitant chemoradiotherapy for advanced head and neck cancer: impact on the natural history of the disease. J Clin Oncol 1995;13:876-83.
14. Forastiere AA. Use of paclitaxel (taxol) in squamous cell carcinoma of the head and neck. Semin Oncol 1993;20:56-60.
15. Athanasiadis I, Vokes EE. Expanding role of chemotherapy for head and neck squamous cell carcinoma. Adv Oncol 1995;11(2):22-9.