Magnetization and diffusion effects in NMR imaging of hyperpolarized substances

Magnetic Resonance in Medicine

Volumn 37, Issue 1, 1997, Pages 153-158

  Gao, J H ^a   Lemen, L ^a   Xiong, J ^a   Patyal, B ^a   Fox, P T ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

blood flow; diffusion; gas; magnetization

Indexed keywords

BLOOD; BLOOD VESSELS; DIFFUSION; GALLIUM; HEMODYNAMICS; INERT GASES; MAGNETIC RESONANCE IMAGING; MAGNETIZATION;

BLOOD FLOW; DIFFUSION EFFECTS; FUNCTIONAL MRI (FMRI); GRADIENT ECHO IMAGING; HYPERPOLARIZATION; MAGNETIZATION CHARACTERISTICS; PULSE SEQUENCE ANALYSIS; TECHNICAL CHALLENGES;

BLOOD GAS ANALYSIS;

HELIUM; HELIUM 3; UNCLASSIFIED DRUG; XENON; XENON 129;

ARTICLE; BLOOD FLOW; DIFFUSION; GAS ANALYSIS; HYPERPOLARIZATION; IMAGE ANALYSIS; LUNG FUNCTION; MAGNETIC FIELD; NUCLEAR MAGNETIC RESONANCE IMAGING;

EID: 0031023709     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.1910370123     Document Type: Article

References (27)

1. 1 M. S. Albert, C. S. Springer, Jr., R. Murphy, A. Wishnia, Relaxation of 129 Xe in model biological systems: on probing the mechanism of general anesthesia, in “Proc., SMRM, 11th Annual Meeting, Berlin, 1992, “ p. 2104.
2. 2 M. S. Albert, C. S. Springer, A. Wishnia, 129 Xe relaxation of catalysis by oxygen, in “Proc., SMRM, 11th Annual Meeting, Berlin, 1992,” p. 4710.
3. 3 M. S. Albert, G. D. Cates, B. Driehuys, W. Happer, B. Saam, C. S. Springer, Jr., A. Wishnia, Biological magnetic resonance imaging using laser‐polarized 129 Xe. Nature 370, 199–201 (1994).
4. 4 H. Middleton, R. D. Black, B. Saam, G. D. Cates, G. P. Cofer, R. Guen‐ther, W. Happer, L. W. Hedlund, G. A. Johnson, K. Juvan, J. Swartz, MR imaging with hyperpolarized 3 He gas. Magn. Reson. Med. 33, 271–275 (1995).
5. 5 M. Albert, V. Schepkin, T. Budinger, Imaging hyperpolarized natural abundant xenon 129 Xe, in “Proc., SMR, 3rd Annual Meeting, Nice, 1995,” p. 1201.
6. 6 M. Albert, V. Schepkin, T. Budinger, Measurement of 129 Xe T 1 in blood to explore the feasibility of byperpolarized 129 Xe MRI. J. Comput. Assist. Tomogr. 19, 975–978 (1995).
7. 7 G. A. Johnson, R. D. Black, G. Cates, G. Cofer, R. Guenther, W. Happer, L. W. Hedlund, H. Middleton, J. Swartz, MRI using hyperpolarized gas, in “Proc., SMR, 3rd Annual Meeting, Nice, 1995,” p. 392.
8. 8 S. Peled, F. A. Jolesz, M. Albert, R. Walsworth, Calculation of spin‐exchanged polarized 129 Xe uptake in tissue for MR applications, in “Proc., SMR, 3rd Annual Meeting, Nice, 1995,” p. 1192.
9. 9 M. E. Wagshul, K. Zhong, A. Wishnia, Hyperpolarized 129 Xe in vivo magnetic resonance spectroscopy in the mouse: T 1 and T 2 measurements and spectral assignments, in “Proc., SMR, 4th Annual Meeting, New York, 1996.” p. 20.
10. 10 G. T. Gullberg, M. A. Simons, F. W. Wehrli, A matheniatical model for signal from spins flowing during the application of spin echo pulse sequences. Magn. Reson. Imaging 6, 437–461 (1988).
11. 11 J.‐H. Gao, S. K. Holland, J. C. Gore, Nuclear magnetic resonance signal from flowing nuclei in rapid imaging using gradient echoes. Med. Phys. 15, 809–814 (1988).
12. 12 R. Carlin, S. Chien, Partition of xenon and iodoantipyrine among erythrocytes, plasma, and myocardium. Circ. Res. 40, 497–504 (1977).
13. 13 R. Carlin, S. Chien, Effects of hematocrit on the washout of xenon and iodoantipyrine from dog myocardium. Circ. Res., 40, 505–509 (1977).
14. 14 E. M. Haacke, T. J. Masaryk, P. A. Wielopolski, F. R. Zypman, J. A. Tkach, S. Amartur, J. Mitchell, M. Clampitt, C. Paschal, Optimizing blood vessel contrast in fast three‐dimensional MKI. Magn. Reson. Med. 14, 202–221 (1990).
15. 15 H. E. Cline, W. E. Lorensen, R. J. Herfkens, G. A. Johnson, G. H. Glover, Vascular morphology by three‐dimensional magnetic resonance imaging. Magn. Reson. Imaging. 7, 45–54 (1990).
16. 16 F. W. Wehrli, E. M. Haacke, Principles of MR imaging, in “ Magnetic Resonance Angiography: Concepts & Applications ” ( E. J. Potchen, E. M. Haacke, J. E. Siebert, A. Gottschalk, Eds.), p. 9–34, Mosby‐Year Book, Inc., St. Louis, 1993.
17. 17 R. G. Shulman, A. M. Blamire, D. L. Rothman, G. McCarthy, Nuclear magnetic resonance imaging and spectroscopy of humnn brain function. Proc. Natl. Acad. Sci. USA 90, 3127–3133 (1933).
18. 18 K. K. Kwong, J. W. Belliveau, D. A. Chesler, I. E. Goldberg, R. M. Weisskoff, B. P. Poncelet, D. N. Kennedy, B. E. Hoppel, M. S. Cohen, R. Turner, H.‐M. Cheng, T. J. Brady, B. R. Rosen, Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc. Natl. Acad. Sci. USA 89, 5675–5679 (1992).
19. 19 S. Lai, A. L. Hopkins, E. M. Haacke, D. Li, B. A. Wasserman, P. Buckley, L. Friedman, H. Meltzer, P. Hedera, R. Friedland, Identification of vascular structures as a major source of signal contrast in high resolution 2D and 3D functional activation imaging of the motor cortex at 1.5 T: preliminary results. Magn. Reson. Med. 30, 387–392 (1993).
20. 20 J. H. Gao, I. Miller, S. Lai, J. Xiong, P. T. Fox, Quantitative assessment of blood inflow effects in functional MRI signals. Magn. Reson. Med. (1996), 36, 314–319 (1996).
21. 21 J. W. Belliveau, D. N. Kennedy, R. C. McKinstry, B. R. Buchbinder, R. M. Weisskoff, M. S. Cohen, J. M. Vevea, T. J. Brady, R. R. Rosen, Functional mapping of the human visual cortex by magnetic resonance imaging. Science 254, 716–719 (1991).
22. 22 A. Abragam, “ The Principles of Nuclear Magnetism.” Oxford University Press, London, 1961.
23. 23 S. J. Riederer, T. Tasciyan, R. Farzanch, J. N. Lee, R. C. Wright, R. J. Herfkens, MR fluoroscopy: technical feasibility. Magn. Reson. Med. 8, 1–15 (1988).
24. 24 P. Mansfield, P. G. Morris, “ NMR Imaging in Biomedicine,” Academic Press, New York, 1982.
25. 25 Z. H. Cho, C. B. Ahn, S. C. Juh, H. K. Lee, Nuclear magnetic resonance microscopy with 4‐μm resolution: theoretical study and experimental results. Med. Phys. 15, 815–824 (1988).
26. 26 S. D. Ogawa, D. W. Tank, R. S. Menon, J. M. Ellermann, S.‐G. Kim, H. Merkle, K. Ugurbil, Intrinsic signal changes accompanying sensory stimulation: functional brain mapping using MRI. Proc. Natl. Acad. Sci. USA 89, 5951–5955 (1992).
27. 27 S. D. Ogawa, R. S. Menon, D. W. Tank, S. ‐G. Kim, H. Merkle, J. M. Ellermann, K. Ugurhil, Functional brain mapping by blood oxygen‐ation level‐dependent contrast magnetic resonance imaging: a comparkon of signal characteristics with a biophysical model. Biophys. J. 64, 803–812 (1992).