Effects of tris(4-chlorophenyl)methanol on the rat following short-term oral exposure

Chemosphere

Volumn 34, Issue 1, 1997, Pages 1-12

  Poon, Raymond ^a   Lecavalier, Pierre ^a   Bergman, Åke ^b   Yagminas, Algis ^a   Chu, Ih ^a   Valli, Victor E ^c  

^a Environmental Health Centre Ottawa   (Canada)

^b STOCKHOLM UNIVERSITY   (Sweden)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; LIVER ENZYME; XENOBIOTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY WEIGHT; CELL PROLIFERATION; ECOTOXICOLOGY; ENZYME ACTIVITY; ERYTHROCYTE COUNT; FEMALE; HYPERPLASIA; LIVER CELL; LIVER WEIGHT; LYMPHOCYTE COUNT; MALE; NONHUMAN; RAT; SMOOTH ENDOPLASMIC RETICULUM; SPLEEN WEIGHT; TIME; TOXICITY TESTING; URINE LEVEL;

EID: 0031023668     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0045-6535(96)00363-3     Document Type: Article

References (29)

1. Burchell, B., and Weatherill, P. (1981). 4-Nitrophenol UDP-glucuronyltransferase (rat liver). In Methods in Enzymology. 77, (W.B. Jakoby, ed), pp. 169-177. Academic Press.
2. Burke, M.D., and Mayer, R.T. (1974). Ethoxyresorufin: direct fluorometric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthere. Drug. Metab. Dispo. 2,583-588.
3. Burke, M.D., Thompson, S., Elcombe, C.R., Halpert, J., Haaparanta, T., and Mayer, R.T. (1985). Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450. Biochem. Pharmacol. 34, 3337-3345.
4. Burns, J.J., Conney, A.H., Dayton, P.G., Evans, C., Martin, G.R., and Taller, D. (1960). Observations on the drug induced synthesis of D-glucuronic, L-gulonic and L-ascorbic acids in rats. J. Pharmacol. Exp. Therap. 129, 132-138.
5. Bursch, W., Düsterberg, B., and Schulte-Hermann, R. (1986). Growth, regression and cell death in rat liver as related to tissue levels of the hepatomitogen cyproterone acetate. Arch. Toxicol. 59, 221-227.
6. Buser, H-R. (1995). DDT, a potential source of environmental tris(4-chlorophenyl)methane and tris(4-chlorophenyl)methanol. Environ. Sci. Technol. 29, 2133-2139.
7. Cochin, J., and Axelrod, J.J. (1959). Biochemical and pharmacological changes in the rat following chronic administration of morphine, nalorphine and normorphine. Pharmacol. Exp. Ther. 125, 105-110.
8. Conney, A.H. (1967). Pharmacological implications of microsomal enzyme induction. Parmacol Rev. 19, 317-366.
9. De Waziers I, Azaïs V. (1987). Drug-metabolizing enzyme activities in the liver and intestine of rats exposed to DDT: Effect of vitamin A status. Arch. Environ. Contamin. Toxicol. 16, 343-348.
10. Flodström, S., Hemming, H., Wängård, L., and Ahlborg, U.G. (1990). Promotion of altered hepatic foci development in rat liver, cytochrome P450 enzyme induction and inhibition of cell-cell communication by DDT and some structurally related organohalogen pesticides. Carcinogenesis 11, 1413-1417.
11. Guengerich, F.P., Dannan, G.A., Wright, S.T., Martin, M.V., and Kaminsky, L.S. (1982). Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or β-napthoflavone Biochem. 21, 6019-6030.
12. Gupta, P.H., Mehta, S., and Mehta, S.K. (1989). Effect of DDT on hepatic mixed-function oxidase activity in normal and vitamin A-deficient rats. Biochem. Int. 19, 247-256.
13. Habig, W.H., Pabst, M.J., and Jakoby, W.B. (1974). Glutathione S-transferase. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 25, 7130-7139.
14. Haraguchi, K., Athanasiadou, M., Bergman, Å., Hovander, L. And Jensen, S. (1992). PCB and PCB methyl sulfones in selected groups of seals from Swedish waters. Ambio 21, 546-549.
15. Hart, L.G., and Fouts, J.R. (1965). Further studies on the stimulation of hepatic microsomal drug metabolizing enzymes by DDT and its analogs. Naunyn-Schmiedebergs Arch. Exp. Path. u. Pharmak. 249, 486-500.
16. Horio, F., and Yoshida, A. (1982). Effects of some xenobiotics on ascorbic acid metabolism in rats. J. Nutr. 112, 416-425.
17. Jarman, W.M., Simon, M., Norstrom, R.J., Burns, S.A., Bacon, C.A., Simonelt, B.R.T., and Risebrough, R. W. (1992). Global distribution of tris(4-chlorophenyl)methanol in high trophic level bird and mammals. Environ. Sci. Technol. 26, 1770-1774.
18. Jonsson, H.T., Walker, Jr. E.M., Greene, W.B., Hughson, M.D., and Hennigar, G.R. (1981). Effects of prolonged exposure to dietary DDT and PCB on rat liver morphology. Arch. Environ. Contam. Toxicol. 10, 171-183.
19. Kerr, J.F.R., Wyllie, A.H., and Currie, A.R. (1972). Apoptosis. A basic biological phenomenon with wide-ranging implication in tissue kinetics. Br. J. Cancer. 26,239-257.
20. Li, H.C., Dehal, S.S., Kupfer, D. (1995). Induction of hepatic CYP2B and CYP3A enzymes by the proestrogenic pesticide methoxychlor and by DDT in the rat. Effects on methoxychlor metabolism. J. Biochem. Toxicol. 10, 51-61.
21. Lubet, R.A., Nims, R.W., Mayer, R.T., Cameron, J.W., and Schectman, L.M. (1985). Measurement of cytochrome P-450 dependent dealkylation of alkoxyphenoxazones in hepatic S9 and hepatocyte homogenates: effects of dicumarol. Mutat. Res. 142, 127-131.
22. Poon, R., Chu, I., Lecavalier, P., Bergman, A., and Villaneuve, D.C. (1994). Urinary ascorbic acid-HPLC determination and application as a noninvasive biomarker of hepatic response. J. Biochem. Toxicol. 9,297-304.
23. Poon, R., Vu, D., and Vincent, R. (1995). N-Acetylglucosaminadase activity in bronchoalveolar lavage fluid -characterization and response to ozone exposure. Inhalation Toxicol. 7.1195-1206.
24. Rahman, M.S., Montanarella, L., Johansson, B., and Larsen, B.R. (1993). Trace levels of Tris(4-chlorophenyl)-methanol and -methane in human milk. Chemosphere 27,1487-1497.
25. Safe, S. (1991). Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzo-p-dioxins (PCDFs) and related compounds: environmental and mechanistic considerations which support the development pf toxic equivalency factors (TEFs). CRC Crit. Rev. Toxicol. 21, 51-88.
26. Schenkman, J.B., Remmer, H., and Estabrook, R.W. (1963). Spectral studies of drug interaction with hepatic microsomal cytochrome. Mol. Pharmacol. 3,113-123.
27. Tephly, T., Townsend, M., Coffman, B., Puig, J., and Green, M. (1988). Characterization of UDP-glucuronosyltransferase from animal and human liver. In "Cellular and Molecular Aspects of Glucuronidation", Ed. G. Siest, J. Magdalou, B. Burchell. Colloque INSERM. John Libbey Eurotext Ltd. 173, pp. 37-42.
28. Walker II, W., Jarman, W.M., de Lappe, B.W., and Tefft, J.A. (1989). Identification of tris(chlorophenyl)methanol in blubber of harbor seals from Puget Sound. Chemosphere 18, 1799-1804.
29. Zook, D-R., Buser, H-R., Bergqvist, P-A., Rappe, C., and Olsson, M. (1992). Detection of tris(chloropheyl)methane and tris(4-chlorophenyl)methanol in Ringed Seal (Phoca hispida) from the Baltic Sea. Ambio 21,557-560.