Effects of allopurinol, ibuprofen and cyclosporin A on local microcirculatory disturbances due to burn injuries

Burns

Volumn 23, Issue 1, 1997, Pages 43-49

  Cetinkale, O ^a,b   Demir, M ^a   Sayman, H B ^a   Ayan, F ^a   Onsel, C ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

^b NONE   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOPURINOL; CYCLOSPORIN A; FREE RADICAL; IBUPROFEN; IMMUNOSUPPRESSIVE AGENT; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BURN; CAPILLARY PERMEABILITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; INTRAVENOUS DRUG ADMINISTRATION; MALE; MICROCIRCULATION; MUSCLE BLOOD FLOW; NEUTROPHIL; NONHUMAN; RAT; SECONDARY PREVENTION; TIME; TISSUE NECROSIS;

ALLOPURINOL; ANALYSIS OF VARIANCE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BURNS; CYCLOSPORINE; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; IBUPROFEN; IMMUNOSUPPRESSIVE AGENTS; INJURY SEVERITY SCORE; MALE; MICROCIRCULATION; RATS; RATS, WISTAR; SKIN;

EID: 0031023214     PISSN: 03054179     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0305-4179(96)00079-4     Document Type: Article

References (21)

1. Kaufman T, Neuman RA, Weinberg A. Is postburn dermal ischemia enhanced by oxygen free radicals? Burns 1989; 15: 291-294.
2. Alexander F, Mathieson M, Teoh KHT et al. Arachidonic acid metabolites mediate early burn edema. J Trauma 1984; 24: 709-712.
3. Choi M, Ehrlich HP. U75412E, a Lazaroid, prevents progressive burn ischemia in a rat model. Am J Pathol 1993; 142: 519-528.
4. Da Costa R, Aggarwal SJ, Diller KR et al. The effects of epinephrine, ibuprofen, and tetrachlorodecaoxide on cutaneous microcirculation in thermally injured hamsters. J Burn Care Rehabil 1992; 13: 396-402.
5. Demling RH, LaLonde C. Early postburn lipid peroxidation: effect of ibuprofen and allopurinol. Surgery 1990; 107: 85-93.
6. Regas FC, Ehrlich HP. Elucidating the vascular response to burns with a new rat model. J Trauma 1992; 32: 557-563.
7. Till GO, Guilds LS, Mahrougui M et al. Role of xanthine oxidase in thermal injury of skin. Am J Pathol 1989; 135: 195-202.
8. Friedl HP, Till GO, Trentz O et al. Roles of histamine, complement and xanthine oxidase in thermal injury of skin. Am J Pathol 1989; 135: 203-217.
9. Weiss SJ. Tissue destruction by neutrophils. N Engl J Med 1989; 320: 365-376.
10. Ferguson MK, Seifert FC, Replogle RL. Leukocyte adherence in venules of rat skeletal muscle following thermal injury. Microvasc Res 1982; 24: 34-41.
11. Mileski W, Gates B, Sigman A et al. Inhibition of leukocyte adherence in a rabbit model of major thermal injury. J Burn Care Rehabil 1993; 14: 610-616.
12. De La Ossa JC, Malago M, Gewertz BL. Neutrophil-endothelial cell binding in neutrophil-mediated tissue injury. J Surg Res 1992; 53: 103-107.
13. Bucky LP, Vedder NB, Hong HZ et al. Reduction of burn injury by inhibiting CD18-mediated leukocyte adherence in rabbits. Plast Reconstr Surg 1994; 93:1473-1480.
14. Mileski W, Borgstrom D, Lightfoot E et al. Inhibition of leukocyte-endothelial adherence following thermal injury. J Surg Res 1992; 52: 334-339.
15. Choi M, Rabb H, Arnaout MA et al. Preventing the infiltration of leukocytes by monoclonal antibody blocks the development of progressive ischaemia in rat burns. Plast Reconstr Surg 1995; 96: 1177-1187.
16. Suzuki S, Toledo-Pereyra LH, Rodriguez FJ et al. Neutrophil infiltration as an important factor in liver ischaemia and reperfusion injury. Modulating effects of FK506 and cyclosporine. Transplantation 1993; 55: 1265-1272.
17. Kawano K, Kim YI, Kaketani K et al. The beneficial effect of cyclosporine on liver ischaemia in rats. Transplantation 1989; 48: 759-764.
18. Kucukcelebi A, Ozcan M. The beneficial effect of cyclosporin-A on the no-reflow phenomenon in rat skin island flaps. Br Plast Surg 1992; 45: 512-514.
19. Shiga Y, Onodera H, Matsuo Y et al. Cyclosporin A protects against ischemia-reperfusion injury in the brain. Brain Res 1992; 595: 145-148.
20. Sayman HB, Urganciglu I, Uslu I et al. Prediction of muscle viability after electrical burn necrosis. Clin Nucl Med 1992; 17: 395-396.
21. UFAW. The UFAW Handbook on the Care and Management of Laboratory Animals, 5th edn. London, 1976: Churchill Livingstone.