Albatrossidine: A large, easily synthesized molecular cleft

Tetrahedron Letters

Volumn 38, Issue 1, 1997, Pages 7-10

  Tong, Ling ^a   Ho, Douglas M ^a   Vogelaar, Nancy J ^a   Schutt, Clarence E ^a   Pascal Jr , Robert A ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PYRIDINE DERIVATIVE;

ARTICLE; CRYSTALLOGRAPHY; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0031022674     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(96)02261-7     Document Type: Article

References (15)

1. Qiao, X.; Padula, M. A.; Ho, D. M.; Vogelaar, N. J.; Schutt, C. E.; Pascal, R. A., Jr. J. Am. Chem. Soc. 1996, 118, 741-745.
2. Scheuing, G.; Winterhalder, L. Liebigs Ann. Chem. 1929,473, 126-136.
3. Wolfe, S.; Pilgrim, W. R.; Garrard, T. F.; Chamberlain, P. Can. J. Chem. 1971,49, 1099-1105.
4. +, 15), 105 (100), 72 (40).
5. +, 100), 662 (M-HCO, 54).
6. 5, 14).
7. 2) = 0.286, and S = 1.08 for 7502 unique reflections and 992 variables.
8. Minor, W. XDISPLAYF Program. Purdue University, 1993.
9. Egert, E.; Sheldrick, G. M. Acta Crystallogr., Sect. A 1985,41, 262-268.
10. Sheldrick, G. M. SHELXL-93. Program for the Refinement of Crystal Structures. University of Gottingen, 1993.
11. Van der Sluis, P.; Spek, A. L. Acta Crystallogr., Sect. A 1990,46, 194-201.
12. Spek, A. L. Acta Crystallogr., Sect. A 1990,46, C34.
13. Pascal, R. A., Jr.; McMillan, W. D.; Van Engen, D.; Eason, R. G. J. Am. Chem. Soc. 1987, 109, 4660-4665; see note 17 for the definition of "end-to-end twist".
14. 3, 500 MHz) δ 5.80 (t, J = 8 Hz, 1H), 5.90 (br s, 2H), 6.05 (br s, 2H), 6.09 (d, J = 8 Hz, 2H), 6.42 (m, 8H), 6.50-6.75 (m, 54H), 6.78 (t, J = 7 Hz, 2H), 6.85 (t, J = 7 Hz, 2H); FAB MS, m/z 1412 (M+H, 100), 1307 (56).
15. 3, 500 MHz) δ 5.72 (t, J = 8 Hz, 1H), 5.93 (d, J = 8 Hz, 2H), 6.05 (m, 6H), 6.23 (t, J = 8 Hz, 2H), 6.30 (d, J = 8 Hz, 2H), 6.33 (t, J = 7 Hz, 2H), 6.40 (m, 4H), 6.52-6.82 (m, 46H), 6.94 (m, 6H), 7.12 (d, J = 7 Hz, 2H); FAB MS, m/z 1412 (M+H, 100), 1307 (46).