Rationally designed inhibitors of inosine monophosphate dehydrogenase

Journal of Medicinal Chemistry

Volumn 40, Issue 1, 1997, Pages 4-8

  Zhang, Han Zhong ^a   Rao, Kotesvar ^a   Carr, Stephen F ^b   Papp, Eva ^b   Straub, Kenneth ^b   Wu, John C ^b,c   Fried, Josef ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b ROCHE BIOSCIENCE   (United States)

^c BAYER AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; INOSINATE DEHYDROGENASE; INOSINE PHOSPHATE;

ARTICLE; COVALENT BOND; DRUG DESIGN; DRUG STRUCTURE; ENZYME DEGRADATION; ENZYME INACTIVATION; ENZYME INHIBITION; HYDROGEN BOND; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; IMP DEHYDROGENASE; MASS SPECTROMETRY; NAD;

EID: 0031022626     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960732v     Document Type: Article

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