Proton relaxation times and interstitial fluid pressure in human melanoma xenografts

British Journal of Cancer

Volumn 75, Issue 2, 1997, Pages 180-183

  Lyng, H ^a   Tufto, I ^a   Skretting, A ^a   Rofstad, E K ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Interstitial fluid pressure; Magnetic resonance imaging; Melanoma xenografts; Relaxation times; Tumour water content

Indexed keywords

PROTON;

ANIMAL EXPERIMENT; ARTICLE; CANCER MODEL; CONTROLLED STUDY; HUMAN; HUMAN CELL; MELANOMA; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; TISSUE PRESSURE; TUMOR XENOGRAFT; WATER CONTENT;

EID: 0031022501     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1997.30     Document Type: Article

References (27)

1. Allas SW, Braffman BH, Lobrutto R, Elder DE and Herlyn D (1990) Human malignant melanomas with varying degree of melanin content in nude mice: MR imaging, histopathology, and electron paramagnetic resonance. J Comput Ass Tomogr 14: 547-554
2. Bakker CJG, De Graff CN and Van Dijk P (1984) Derivation of quantitative information in NMR imaging: a phantom study. Phys Med Biol 29: 1511-1525
3. Belfi CA, Medendorp SV and NGO Fqh (1991) The response of the KHT sarcoma to radiotherapy as measured by water proton NMR relaxation times: relationships with tumor volume and water content. Int J Radiat Oncol Biol Phys 20: 497-507
4. Boucher Y, Baxter LT and Jain RK (1990) Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapy. Cancer Res 50: 4478-4484
5. Boucher Y, Kirkwood JM, Opacic D, Desantis M and Jain RK (1991) Interstitial hypertension in superficial metastatic melanomas in humans. Cancer Res 51: 6691-6694
6. Boucher Y and Jain RK (1992) Microvascular pressure is the principal driving force for interstitial hypertension in solid tumours: implications for vascular collapse. Cancer Res 52: 5110-5114
7. Bradwell AR, Fairweather DS, Dykes PW, Keeling A, Vaughan A and Taylor J (1985) Limiting factors in the localization of tumors with radiolabeled antibodies. Immunol Today 6: 163-170
8. 1H NMR relaxation times and water compartmentalization in experimental tumor models. Magn Reson Imaging 4: 335-342
9. Cobb LM (1989) Intratumour factors influencing the access of antibody to tumour cells. Cancer Immunol Immunother 28: 235-240
10. Curti BD, Urba WJ, Alvord WG, Janik JE, Smith JW, Madara K and Longo DL (1993) Interstitial pressure of subcutaneous nodules in melanoma and lymphoma patients: changes during treatment. Cancer Res 53: 2204-2207
11. Fadnes HO, Reed R and Aukland K (1977) Interstitial fluid pressure in rats measured with a modified wick technique. Microvasc Res 14: 27-36
12. Jain RK (1987) Transport of molecules in the tumor interstitium: a review. Cancer Res 47: 3039-3051
13. Jain RK and Baxter LT (1988) Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure. Cancer Res 48: 7022-7032
14. Jakobsen I, Kaalhus O, Lyng H and Rofstad EK (1995) Detection of necrosis in human tumour xenografts by proton magnetic resonance imaging. Br J Cancer 71: 456-461.
15. Jones PL, Gallagher BM and Sands H (1986) Autoradiographic analysis of monoclonal antibody distribution in human colon and breast tumor xenografts. Cancer Immunol Immunother 22: 139-143
16. Kristjansen PEG, Boucher Y and Jain RK (1993) Dexamethasone reduces the interstitial fluid pressure in a human colon adenocarcinoma xenograft. Cancer Res 53: 4764-4766
17. Lee I, Boucher Y and Jain RK (1992) Nicotinamide can lower tumor interstitial fluid pressure: mechanistic and therapeutic implications. Cancer Res 52: 3237-3240
18. Less JR, Posner MC, Boucher Y, Borochovitz D, Wolmark N and Jain RK (1992) Interstitial hypertension in human breast and colorectal tumors. Cancer Res 52: 6371-6374
19. Leunig M, Goetz AE, Gamarra F, Zetterer G, Messmer K and Jain RK (1994) Photodynamic therapy-induced alterations in interstitial fluid pressure, volume and water content of an amelanotic melanoma in the hamster. Br J. Cancer 69: 101-103
20. Rofstad EK (1994) Orthotopic human melanoma xenograft model systems for studies of tumour angiogenesis, pathophysiology, treatment sensitivity and metastatic pattern. Br J Cancer 70: 804-812
21. Rofstad EK, Steinsland E, Kaalhus O, Chang YB, Høvik B and Lyng H (1994) Magnetic resonance imaging of human melanoma xenografts in vivo: proton spin-lattice and spin-spin relaxation times versus fractional tumour water content and fraction of necrotic tumour tissue. Int J Radiat Biol 65: 387-402
22. Sands H, Jones PL, Shah SA, Palme D, Vessella RL and Gallagher BM (1988) Correlation of vascular permeability and blood flow with monoclonal antibody uptake by human Clouser and renal cell xenografts. Cancer Res, 48, 188-193
23. 2 images. Med Phys 10: 642-645.
24. 1H MR imaging. Am J Roentgenol 158: 259-264.
25. Tufto I and Rofstad EK (1995) Interstitial fluid pressure in human melanoma xenografts. Relationship to fractional tumor water content, tumor size, and tumor volume-doubling time. Acta Oncol 34: 361-365.
26. Zlotecki RA, Boucher Y, Lee I, Baxter LT and Jain RK (1993) Effect of angiotensin II induced hypertension on tumor blood flow and interstitial fluid pressure. Cancer Res 53: 2466-2468.
27. Znati CA, Rosenstein M, Boucher Y, Epperly MW, Bloomer WD and Jain RK (1996) Effect of radiation on interstitial fluid pressure and oxygenation in a human tumor xenograft. Cancer Res 56: 964-968