In vitro amoebicidal activity of propamidine and pentamidine isethionate against Acanthamoeba species and toxicity to corneal tissues

Cornea

Volumn 16, Issue 1, 1997, Pages 94-100

  Alizadeh, Hassan ^a,c   Silvany, Robert E ^a   Meyer, Dale R ^d   Dougherty, Joel M ^b   McCulley, James P ^a  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d NONE

Author keywords

Acanthamoeba; Cornea; Endothelium; Epithelium; In vitro toxicity; Keratitis; Pentamidine; Propamidine

Indexed keywords

PENTAMIDINE ISETHIONATE; PROPAMIDINE ISETHIONATE;

ACANTHAMOEBA; ANIMAL CELL; ANIMAL TISSUE; ANTIBIOTIC RESISTANCE; ARTICLE; BIOCOMPATIBILITY; CELL CULTURE; CORNEA EPITHELIUM; DRUG POTENCY; DRUG SENSITIVITY; ENDOTHELIUM; KERATITIS; NONHUMAN; PRIORITY JOURNAL; RABBIT; SPECIES DIFFERENCE;

EID: 0031022493     PISSN: 02773740     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003226-199701000-00016     Document Type: Article

References (40)

1. Hirst LW, Green WR, Merz W, et al. Management of Acanthamoeba keratitis: a case report and review of the literature. Ophthalmology 1985;91:1105-11.
2. Samples JR, Binder PS, Luibel FJ, et al. Acanthamoeba keratitis possibly acquired from a hot tub. Arch Ophthalmol 1984;102:707-10.
3. Wright P, Warhurst D, Jones BR. Acanthamoeba keratitis successfully treated medically. Br J Ophthalmol 1985;69; 778-82.
4. Cohen EEJ, Buchanan HW, Laughrea PA, et al. Diagnosis and management of Acanthamoeba keratitis. Am J Ophthalmol 1985;100:389-95.
5. Moore MB, McCulley JP, Luckenbach M, et al. Acanthamoeba keratitis associated with soft contact lenses. Am J Ophthalmol 1985;100:396-403.
6. Blackman HJ, Rao NA, Lemp MA, et al. Acanthamoeba keratitis successfully treated with penetrating keratoplasty: suggested immunogenic mechanisms of action. Cornea 1984; 3:125-30.
7. Wilhelmus KR, Osato MS, Font RL, et al. Rapid diagnosis of Acanthamoeba keratitis using calcofluor white. Arch Ophthalmol 1986;104:1309-12.
8. Mannis MJ, Tamaru R, Roth AM, et al. Acanthamoeba sclerokeratitis. Arch Ophthalmol 1986;104:1313-17.
9. Epstein RJ, Wilson LA, Visvesvara GS, et al. Rapid diagnosis of Acanthamoeba keratitis from corneal scrapings using indirect fluorescent antibody staining. Arch Ophthalmol 1986;104:1318-21.
10. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises (Case 10-1985). N Engl J Med 1985;312:634-41.
11. Moore MB, McCulley JP, Kaufman HE, et al. Radial keratoneuritis as a presenting sign in Acanthamoeba keratitis. Ophthalmology 1986;93:1310-15.
12. Newton C, Driebe WT, Groden LR, et al. Acanthamoeba keratitis associated with contact lenses - United States. MMWR 1986;35:405-8.
13. Jones DB. Acanthamoeba: the ultimate opportunist? Am J Ophthalmol 1986;102:527-30.
14. Moore MB, McCulley JP, Newton C, et al. Acanthamoeba keratitis: a growing problem in soft and hard contact lens wearers. Ophthalmology 1987;94:1654-61.
15. Auran JD, Starr MB, Jakobiec FA. Acanthamoeba keratitis: a review of the literature. Cornea 1987;6:2-26.
16. Casemore DP. Sensitivity of Hartmanella (Acanthamoeba) to 5-fluorocystosine, hydroxystilbamidine, and other substances. J Clin Pathol 1970;23:649-52.
17. Nagington J. Isolation of amoebae from eye infections in England. Trans Ophthalmol Soc UK 1975;95:207-9.
18. Warhurst DC, Stamm WP, Phillips EA. Acanthamoeba from a new case of corneal ulcers. Trans R Soc Trop Med Hyg 1976;170:279.
19. Duma RJ, Finley R. In vitro susceptibility of pathogenic Naegleria and Acanthamoeba species to a variety of therapeutic agents. Antimicrob Agents Chemother 1976;10:370-6.
20. Ferrante A, Rowan-Kelly B, Thong YH. In vitro sensitivity of virulent Acanthamoeba culbertsoni to a variety of drugs and antibiotics. Int J Parasitol 1984;14:53-6.
21. Moore MB, McCulley JP. Letter to the editor. Am J Ophthalmol 1987;104:310-11.
22. Moore MB. Acanthamoeba keratitis. Arch Ophthalmol 1988;106:1181-3.
23. Moore MB, McCulley JP. Acanthamoeba keratitis associated with contact lenses: six cases of successful medical management. Br J Ophthalmol 1989;73:271-5.
24. Philips E, Nash P. Culture media. In: Lenette EH, Balows A, Housler WJ Jr, Shadeng JH, eds. Manual of clinical microbiology, 4th ed. Washington, DC: American Society for Microbiology, 1985:1077.
25. Visvesvara GS, Mirre SS, Branalt FH, et al. Isolation of two strains of Acanthamoeba castellanii from human tissue and their pathogenicity and isoenzyme profiles. J Clin Microbiol 1983;18:1405-12.
26. Silvany RE, Dougherty JM, McCulley JP, et al. The effect of currently available contact lens disinfection systems on Acanthamoeba castellanii and Acanthamoeba polyphaga. Ophthalmology 1990;97:286-90.
27. Johnson-Muller BJ, Gross J. Regulation of corneal collagenase production: epithelial-strand cell interactions. Proc Natl Acad Sci USA 1978;75:4417-21.
28. Meyer DR, McCulley JP. Acute and protracted injury to corneal epithelium as an indication of the biocompatibility of various pharmaceutical vehicles. In: Goldberg AM, ed. Progress in in vitro toxicology, alternative methods in toxicology, vol 6. New York: Mary Ann Liebert, 1988:215-35.
29. Meyer DR, McCulley JP, Stern ME. The importance of vehicle composition, osmolality, and pH for the in vitro assessments of intraocular dry toxicity. In: Goldberg AM, ed. In vitro toxicology, a progress report from the Johns Hopkins Center for Alternatives to Animal Testing, alternative methods in toxicology, vol 3. New York: Mary Ann Liebert, 1985:607-23.
30. Meyer DR, McCulley JP. Evaluation of the comparative toxicity of intraocular viscoelastic preparations. In: Goldberg AM, ed. In vitro toxicology: approaches to validation, alternative methods in toxicology, vol 5. New York: Mary Ann Liebert, 1987:393-410.
31. Takahashi N. Quantitative cytotoxicity of preservatives evaluated in cell culture with Chang's human conjunctival cells - effect of temperature on cytotoxicity. Jpn J Ophthalmol 1982;26:234-8.
32. Lowry OH, Rosenbrough NJ, Farr AL, et al. Protein measurement with the folin phenol reagent. J Biol Chem 1951; 193:265-75.
33. Takahashi N. A new method evaluating quantitative time-dependent cytotoxicity of ophthalmic solution in cell culture: beta-adrenergic blocking agents. Graefes Arch Clin Exp Ophthalmol 1983;220:264-7.
34. Johns KJ, Heard WS, O'Day DM. Corneal toxicity of propamidine. Arch Ophthalmol 1988;106:68-9.
35. Stevens AR, Willaert E. Drug sensitivity and resistance of four Acanthamoeba species. Trans R Soc Trop Med Hyg 1980;74:806-8.
36. Prosaad BWK. In vitro effect of drugs against pathogenic and nonpathogenic free-living amoebae and an anaerobic amoeba. Indian J Exp Biol 1972;10:43-5.
37. Kasprzak W, Mazur T, Rucka A. Studies on some pathogenic strains of free-living amoeba isolated from lakes in Poland. Ann Soc Belge Med Trop 1974;54:351-7.
38. Stevens AR, O'Dell WD. In vitro and in vivo activity of 5-fluorocystosine on Acanthamoeba. Antimicrob Agents Chemother 1974;6:282-9.
39. Schoenbach EB, Greenspan EM. The pharmacology, mode of action and therapeutic potentialities of stilbamidine, pentamidine, propamidine, and other aromatic diamidines: a review. Medicine 1948;24:327-77.
40. Sands M, Kron MA, Brown RB. Pentamidine: a review. Rev Invest Dis 1985;7:625-34.