메뉴 건너뛰기




Volumn 38, Issue 3, 1997, Pages 399-402

Chemoselective inhibition of the hydrogenolysis of the MPM protective group for phenolic hydroxy functions using a Pd/C-pyridine catalyst

Author keywords

[No Author keywords available]

Indexed keywords

ETHER DERIVATIVE;

EID: 0031022264     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(96)02309-X     Document Type: Article
Times cited : (59)

References (17)
  • 2
  • 9
    • 0342568822 scopus 로고    scopus 로고
    • Satisfactory analytical data were obtained for all new compounds
    • Satisfactory analytical data were obtained for all new compounds.
  • 14
    • 0342568820 scopus 로고    scopus 로고
    • note
    • 4 soln. (not for product 11) and water and evaporated to give a product. The product was purified with silica gel column chromatography if necessary.
  • 15
    • 0343438778 scopus 로고    scopus 로고
    • 2 the smooth cleavage of O-benzyl protection of Boc-Tyr(Bn)-OH under the hydrogenolysis condition with a Pd/C-ammonia system (30 min, 89 %)
    • 2 the smooth cleavage of O-benzyl protection of Boc-Tyr(Bn)-OH under the hydrogenolysis condition with a Pd/C-ammonia system (30 min, 89 %).
  • 16
    • 0342568818 scopus 로고    scopus 로고
    • Under the hydrogenolysis condition without pyridine, reasonably selective removal of the Cbz protecting group of 6 was also observed due to the effect of the amino group of the product 7
    • Under the hydrogenolysis condition without pyridine, reasonably selective removal of the Cbz protecting group of 6 was also observed due to the effect of the amino group of the product 7.
  • 17
    • 0343874583 scopus 로고    scopus 로고
    • note
    • 7 that the selective removal of an aliphatic O-benzyl protection in the presence of a MPM protective group for aliphatic hydroxy functions was achieved with hydrogenolysis over W-4 Raney nickel, although a large excess amount of catalyst was required to complete the reaction.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.