Bacitracin significantly reduces degradation of peptides in plant cell cultures

Biotechnology and Bioengineering

Volumn 53, Issue 2, 1997, Pages 226-231

  Bateman, K S ^a   Congiu, M ^b   Tregear, G W ^b   Clarke, A E ^a   Anderson, M A ^a,c  

^a School of Botany   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c LA TROBE UNIVERSITY   (Australia)

Author keywords

bacitracin; peptide; plant cell culture; protease

Indexed keywords

COMPOSITION EFFECTS; DEGRADATION; ENZYMES; PLANT CELL CULTURE;

ARGININE VASOPRESSIN (AVP) PEPTIDE; BACITRACIN; PEPTIDE HORMONES; PROTEASES;

HORMONES;

BACITRACIN; PEPTIDE; PROTEINASE;

ARTICLE; BIOTECHNOLOGY; CELL CULTURE; CELL VIABILITY; NONHUMAN; PLANT CELL; PROTEIN DEGRADATION; PROTEIN STABILITY;

EID: 0031021810     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19970120)53:2<226::AID-BIT14>3.0.CO;2-I     Document Type: Article

References (30)

1. Bachmair, A., Becker, F., Schell, J. 1993. Use of a reporter transgene to generate Arabidopsis mutants in ubiquitin-dependent protein degradation. Proc. Natl. Acad. Sci. USA 90: 418-421.
2. Bonner, C. A., Kenyon, C., Jensen, R. A. 1988. Physiological and biochemical characterization of a suspension-culture system for sustained exponential growth of Nicotiana silvestris. Physiol. Plant. 74: 1-10.
3. Broekhuijsen, M. P., Mattem, I. E., Contreras, R., Kinghorn, J. R., van den Hondel, C. A. M. J. J. 1993. Secretion of heterologous proteins by Aspergillus niger: Production of active human interleukin-6 in a protease-deficient mutant by KEX2-like processing of a glucoamylase-hIL6 fusion protein. J. Biotechnol. 31: 135-145.
4. Desbuquois, B., Krug, F., Cuatrecasas, P. 1974. Inhibitors of glucagon inactivation. Effect on glucagon-receptor interactions and glucagon-stimulated adenylate cyclase activity in liver cell membranes. Biochim. Biophys. Acta 343: 101-120.
5. Ericson, M. C., Gafford, J., Elbein, A. D. 1978. Bacitracin inhibits the synthesis of lipid-linked saccharides and glycoproteins in plants. Plant Physiol. 62: 373-376.
6. Findlay, D. M., Michelangeli, V. P., Moseley, J. M., Martin, T. J. 1981. Calcitonin binding and degradation by two cultured human breast cancer cell lines (MCF 7 and T 47D). Biochem. J. 196: 513-520.
7. Gibson, A. H., Child, J. J., Pagan, J. D., Scowcroft, W. R. 1976. The induction of nitrogenase activity in Rhizobium by non-legume plant cells. Planta 128: 233-239.
8. Hamamoto, H., Sugiyama, Y., Nakagawa, N., Hashida, E., Matsunaga, Y., Takemoto, S., Watanabe, Y., Okada, Y. 1993. A new tobacco mosaic virus vector and its use for the systemic production of angiotensin-I-converting enzyme inhibitor in transgenic tobacco and tomato. Bio/Technology 11: 930-932.
9. 125I-insulin is associated with an increase in plasma membrane bound insulin and a potentiation of glucose oxidation by adipocytes. J. Biol. Chem. 257: 11563-11570.
10. Horne, R. S. C., MacIsaac, R. J., Moritz, K. M., Tangalakis, K., Wintour, E. M. 1993. Effect of arginine vasopressin and parathyroid hormone-related protein on renal function in the ovine foetus. Clin. Exp. Pharmacol. Physiol. 20: 569-577.
11. Jentsch, S., Bachmair, A. 1992. Principles of protein turnover: possible manipulations, pp. 221-228. In: A. R. Rees, M. J. E. Sternberg, and R. Wetzel (eds.), Protein engineering: a practical approach. Oxford University Press, Oxford.
12. Kaushal, G. P., Szumilo, T., Elbein, A. D. 1988. Structure and biosynthesis of plant N-linked glycoproteins, pp. 421-463. In: J. Preiss (ed.), The biochemistry of plants, vol. 14. Academic Press, San Diego, CA.
13. Krebbers, E., Vandekerckhove, J. 1990. Production of peptides in plant seeds. Trends Biotechnol. 8: 1-3.
14. Krebbers, E., van Rompaey, J., Vandekerckhove, J. 1993. Expression of modified seed storage proteins in transgenic plants, pp. 37-60. In: A. Hiatt (ed.) Transgenic plants: fundamentals and applications. Marcel Dekker, New York.
15. Llewellyn, D. J., Finnegan, E. J., Ellis, J. G., Dennis, E. S., Peacock, W. J. 1987. Structure and expression of an alcohol dehydrogenase 1 gene from Pisum sativum (cv. "Greenfeast"). J. Mol. Biol. 195: 115-123.
16. Manning, M., Olma, A., Klis, W., Kolodziejczyk, A., Nawrocka, E., Misicka, A., Seto, J., Sawyer, W. H. 1984. Carboxy terminus of vasopressin required for activity but not binding. Nature (London) 308: 652-653.
17. Medora, R. S., Mell, G. P., Bilderback, D. E. 1984. Effect of various media on growth and protease production in Carica papaya L. callus cultures. Z. Pflanzenphysiol. 114: 179-185.
18. Meerman, H. J., Georgiou, G. 1994. Construction and characterization of a set of E. coli strains deficient in all known loci affecting the proteolytic stability of secreted recombinant proteins. Bio/Technology 12: 1107-1110.
19. Nassar, A. H., Newbury, H. J. 1987. Ficin production by callus cultures of Ficus carica. J. Plant Physiol. 131: 171-179.
20. Roth, R. A. 1981. Bacitracin: an inhibitor of the insulin degrading activity of glutathione-insulin transhydrogenase. Biochem. Biophys. Res. Commun. 98: 431-438.
21. Shen, S. H. 1984. Multiple joined genes prevent product degradation in Escherichia coli. Proc. Nat. Acad. Sci. USA 81: 4627-4631.
22. Storm, D. R., Toscano, W. A., Jr. 1979. Bacitracin, pp. 1-17. In: F. E. Hahn (ed.), Antibiotics, vol. 5, part 1. Springer, Berlin.
23. Takamatsu, N., Watanabe, Y., Yanagi, H., Meshi, T., Shiba, T., Okada, Y. 1990. Production of enkephalin in tobacco protoplasts using tobacco mosaic virus RNA vector. FEBS Lett. 269: 73-76.
24. Ukaji, T., Ashihara, H. 1987. Effect of inorganic phosphate on the levels of amino acids in suspension-cultured cells of Catharanthus roseus. Ann. Bot. (London) 60: 109-114.
25. Vandekerckhove, J., van Damme, J., van Lijsebettens, M., Botterman, J., de Block, M., Vandewiele, M., de Clercq, A., Leemans, J., van Montagu, M., Krebbers, E. 1989. Enkephalins produced in transgenic plants using modified 2S seed storage proteins. Bio/Technology 7: 929-932.
26. van Noort, J. M., van den Berg, P., Mattern, I. E. 1991. Visualization of proteases within a complex sample following their selective retention on immobilized bacitracin, a peptide antibiotic. Anal. Biochem. 198: 385-390.
27. Wink, M. 1984. Evidence for an extracellular lytic compartment of plant cell suspension cultures: the cell culture medium. Naturwissenschaften 71: 635-637.
28. Wink, M. 1985. Composition of the spent cell culture medium. I. Time-course of ethanol formation and the excretion of hydrolytic enzymes into the medium of suspension-cultured cells of Lupinus polyphyllus. J. Plant Physiol. 121: 287-293.
29. Wink, M. 1994. The cell culture medium - a functional extracellular compartment of suspension-cultured cells. Plant Cell, Tissue Organ Cult. 38: 307-319.
30. Yamamoto, H., Tanaka, S., Fukui, H., Tabata, M. 1986. Enzymatic difference between laticifers and cultured cells of papaya. Plant Cell Rep. 5: 269-272.