Effect of chronic daily ozone exposure on Clara cell secretory protein mRNA expression in the adult rat lung

Experimental Lung Research

Volumn 23, Issue 1, 1997, Pages 51-64

  Royce, Fred H ^a   Plopper, Charles G ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Clara cell secretory protein (CCSP); gene expression; housekeeping genes; ozone

Indexed keywords

MESSENGER RNA; OZONE; SECRETORY PROTEIN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLARA CELL; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HOUSEKEEPING GENE; LONG TERM EXPOSURE; LUNG TOXICITY; MALE; NONHUMAN; PRIORITY JOURNAL;

EID: 0031021362     PISSN: 01902148     EISSN: None     Source Type: Journal    
DOI: 10.3109/01902149709046047     Document Type: Article

References (43)

1. Lippmann M. Health effects of ozone: a critical review. J Air Pollut Control Assoc. 1983;54: 1345-1352.
2. 3-induced change in bronchial reactivity to methacholine and airway inflammation. J Appl Physiol. 1986;60:1321-1326.
3. Koren HS, Devlin RB, Graham DE, et al. Ozone-induced inflammation in the lower airways of human subjects. Am Rev Respir Dis. 1989;139:407-415.
4. Kehrl H, Vincent LM, Kowalsky RJ, et al. Ozone exposure increases respiratory epithelial permeability in humans. Am Rev Respir Dis. 1987;135:1124-1128.
5. Kinney PL, Ware JH, Spengler JD, Dockery DW, Speizer FE, Ferris BGJ. Short term pulmonary change in association with ozone levels. Am Rev Respir Dis. 1989;139:56-61.
6. Horstman D, Folinsbee L, Ives PJ, Abdul-Salaam S, McDonnell WF. Ozone concentration and pulmonary response relationships to 6.6 hour exposures with five hours of moderate exercise to 0.08, 0.10 and 0.12 ppm. Am Rev Respir Dis. 1990;142:1158-1163.
7. Folinsbee LJ, McDonnell WF, Horstman DH. Pulmonary function and symptom responses after 6.6 hour exposure to 0.12 pm ozone with moderate exercise. J Air Pollut Control Assoc. 1988; 38:28-35.
8. Patra AL, Gooya A, Menache MA. A morphometric comparison of the nasalpharyngeal airway of laboratory animals and humans. Anal Rec. 1986;215:42-50.
9. Miller FJ, Overton JH, Jaskot RH, Menzel DB. A model of the regional uptake of gaseous pollutants in the lung: I. The sensitivity of the uptake of ozone in the human lung to lower respiratory tract secretions and exercise. Toxicol Appl Pharmacol. 1985;79:11-27.
10. Plopper CG, Dungworth DL, Tyler WS. Pulmonary lesions in rats exposed to ozone: a correlated light and electron microscopic study. Am J Pathol. 1973;71:375-394.
11. Stephens RJ, Sloan MF, Evans MJ, Freeman G. Early response of lungs to low levels of ozone. Am J Pathol. 1974;74:31-44.
12. Pino MV, Levin JR, Stovall MY, Hyde DM. Pulmonary inflammation and epithelial injury in response to acute ozone exposure in the rat. Toxicol Appl Pharmacol. 1992;112:64-72.
13. Moore PF, Schwartz LW. Morphological effects of prolonged exposure to ozone and sulfuric acid aerosol on the rat lung. Exp Mol Pathol. 1981;35:108-123.
14. Hiroshima K, Kohno T, Owada H, Hayashi Y. A morphological study of the effects of ozone on rat lung. I: short term exposure. Exp Mol Pathol. 1987;47:327-345.
15. Lum H, Schwartz LW, Dungworth DL, Tyler WS. A comparative study of cell renewal alter exposure to ozone or oxygen. Am Rev Respir Dis. 1978;118:335-345.
16. Tyler WS, Tyler NK, Last JA, Barstow TJ, Magliano DJ, Hinds DM. Effects of ozone on lung and somatic growth: pair fed rats after ozone exposure and recovery periods. Toxicology. 1987;46:1-20.
17. Barr BC, Hyde DM, Plopper CG, Dungworth DL. Distal airway remodeling in rats chronically exposed to ozone. Am Rev Respir Dis. 1988;137:924-938.
18. Dodge DE, Rucker RB, Pinkerton KE, Haselton CJ, Plopper CG. Dose-dependent tolerance to ozone. Toxicol Appl Pharmacol. 1994;127:109-123.
19. Penha PD, Werthamer S. Pulmonary lesions induced by long-term exposure to ozone, II: ultrastructure observations of proliferative and regressive lesions. Arch Environ Health. 1974;29: 282-289.
20. Plopper CG, Chow CK, Dungworth DL, Brumme M, Nemeth TJ. Effect of low level of ozone on rat lungs, II: morphological responses during recovery and re-exposure. Exp Mol Pathol. 1978; 29:400-411.
21. Umland TC, Swaminathan S, Furey W, Singh G, Pletcher J, Sax M. Refined structure of rat Clara cell 17 kDa protein at 3.0 A resolution. J Mol Biol. 1992;224:441-448.
22. Katyal SL, Singh G, Brown WE, Kennedy AL, Squeglia N, Chong MW. Clara cell secretory (10 kdaltons) protein: amino acid and cDNA nucleotide sequences, and developmental expression. In: von Wichert P, Muller B, eds. Progress in Respiratory Research. Basel: Karger; 1990:29-35.
23. Patton SE, Gilmore LB, Jetten AM, Nettesheim P, Hook GER. Biosynthesis and release of proteins by isolated pulmonary Clara cells. Exp Lung Res. 1986;11:277-294.
24. Nordlund-Moller L, Andersson O, Ahlgren R, et al. Cloning, structure, and expression of a rat binding protein for polychlorinated biphenyls. J Biol Chem. 1990;265:12690-12693.
25. Boyd MR, Statham CN, Longo WS. The pulmonary clara cell as a target for toxic chemicals requiring metabolic activation: studies with carbon tetrachloride. J Pharmacol Exp Ther. 1980; 212:109-114.
26. Devereux TR, Serabjit-Singh J, Slaughter SR, Wolf CR, Philpot RM, Fouts JR. Identification of cytochrome P-450 isoenzymes in nonciliated bronchiolar epithelial (Clara) and alveolar type II cells isolated from rabbit lung. Exp Lung Res. 1981;2:221-230.
27. Voigt J, Kawabata T, Burke J, Martin M, Guengerich F, Baron J. In situ localization and distribution of xenobiotic activating enzymes and aryl hydrocarbon hydroxylase activity in lungs of untreated rats. Mol Pharmacol. 1990;37:182-191.
28. Baron J, Burke JP, Guengerich FP, Jakoby WB, Voigt JM. Sites for xenobiotic activation and detoxification within the respiratory tract: Implications for chemically induced toxicity. Toxicol Appl Pharmacol. 1988;93:493-505.
29. Singh G, Katyal SL, Brown WE, Kennedy AL, Singh U, Wong-Chong M. Clara cell 10 kDa protein (CC10): comparison of structure and function to uteroglobin. Biochim Biophys Acta. 1990;1039:348-355.
30. Mihal K, Riedel N. One gene encoding three proteins with different functions. Am J Respir Cell Mol Biol. 1991;5:1-3.
31. Miele L, Cordella-Miele F., Mukherjee AB. Uteroglobin: structure, molecular biology, and new perspectives on its function as a phospholipase A2 inhibitor. Endocr Rev. 1987;8:474-490.
32. Gupta RP, Patton SE, Jetten AM, Hook GER. Purification, characterization and proteinase-inhibitory activity of a Clara-cell secretory protein from the pulmonary extracellular lining of rabbits. Biochem J. 1987;248:337-344.
33. Barr BC, Hyde DM, Plopper CG, Dungworth DL. A comparison of terminal airway remodeling in chronic daily versus episodic ozone exposure. Toxicol Appl Pharmacol. 1990;106:384-407.
34. Measurement principle and calibration procedure for the measurement ozone in the atmosphere. Environmental Protection Agency, Title 40, 1988.
35. Dodge DF, Rucker RB, Singli G, Plopper CG. Quantitative comparison of intracellular concentration and volume of Clara cell secretory protein in rat bronchi and bronchioles based on laser scanning confocal microscopy. J Histochem Cytochem. 1993;41:1171-1183.
36. Chomczynski P, Sachi N. Single step methods of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 1987;162: 156-159.
37. Hackett BP, Shimizu N, Gitlin JD. Clara cell secretory protein gene expression in bronchiolar epithelium. Am J Physiol. (Lung Cell Mol Physiol.) 1992;262:L399-L404.
38. Lucas LR, Mize RR, Harlan RE. Semiquantitative analysis of in-situ hybridization results using IMAGE software: a rapid method for counting reduced silver grains over mRNA-positive cells. J Neurosci Methods. 1994;52:101-109.
39. Devereux TR, Domin BA, Philpot RM. Xenobiotic metabolism by isolated pulmonary cells. Pharmacol Ther. 1989;41:243-256.
40. Plopper CG, Chang A, Pang A, Buckpitt AR. Use of microdissected airways to define metabolism and cytotoxicity in murine bronchiolar epithelium. Exp Lung Res. 1991;17:197-212.
41. Duan X, Buckpitt AR, Plopper CR. Variation in antioxidant enzyme activities in anatomic subcompartments within rat and rhesus monkey lung. Toxicol Appl Pharmacol. 1993;123:73-82.
42. Plopper CG, Duan X, Buckpitt AR, Pinkerton KE. Dose-dependent tolerance to ozone. Toxicol Appl Pharmacol. 1994;127:124-131.
43. Royce FH, Van Winkle LS, Yin J, Plopper CG. Comparison of regional variability in lung-specific gene expression using a novel method for RNA isolation from lung subcompartments of rats and mice. Am J Pathol. 1996;148:1779-1786.