Overexpression of androgen-binding protein/sex hormone-binding globulin in male transgenic mice: Tissue distribution and phenotypic disorders

Biology of Reproduction

Volumn 56, Issue 1, 1997, Pages 21-32

  Joseph, David R ^a,b   O'Brien, Deborah A ^a   Sullivan, Patrick M ^a   Becchis, Marzia ^a,c   Tsuruta, James K ^a   Petrusz, Peter ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN BINDING PROTEIN; BINDING PROTEIN; SEX HORMONE BINDING GLOBULIN;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENETIC REGULATION; IMMUNOHISTOCHEMISTRY; MOUSE; MULTINUCLEAR CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SERTOLI CELL; SPERMATOGENESIS; TISSUE DISTRIBUTION; TRANSGENE;

ANDROGEN-BINDING PROTEIN; ANIMALS; BLOTTING, NORTHERN; BRAIN CHEMISTRY; DIHYDROTESTOSTERONE; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; EPIDIDYMIS; GENE EXPRESSION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; PHENOTYPE; PROTEINS; RATS; RNA, MESSENGER; SERTOLI CELLS; SEX HORMONE-BINDING GLOBULIN; SPERMATOGENESIS; TESTIS; TESTOSTERONE; TISSUE DISTRIBUTION;

EID: 0031021077     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod56.1.21     Document Type: Article

References (57)

1. Joseph DR. Structure, function, and regulation of androgen-binding protein/sex hormone-binding globulin. Vitam Horm 1994; 49:197-280.
2. Hammond GL. Molecular properties of corticosteroid binding globulin and the sex steroid binding proteins. Endocr Rev 1990; 11:65-79.
3. Westphal U. Monographs on Endocrinology Berlin: Springer-Verlag; 1986: 198-301.
4. Rosner W. The functions of corticosteroid-binding globulin and sex hormone-binding globulin: recent advances. Endocr Rev 1990; 11:80-91.
5. Joseph DR, Hall SH, Conti M, French FS. The gene structure of rat androgen-binding protein: identification of potential regulatory deoxyribonucleic acid elements of a follicle-stimulating hormone-regulated protein. Mol Endocrinol 1988; 2:3-13.
6. Hammond GL, Underhill DA, Rykse HM, Smith CL. The human sex hormone-binding globulin gene contains exons for androgen-binding protein and two other testicular messenger RNAs. Mol Endocrinol 1989; 3:1869-1876.
7. Danzo BJ, Black JH, Bell BW. Analysis of the oligosaccharides on androgen-binding proteins: implications concerning their role in structure/function relationships. J Steroid Biochem Mol Biol 1991; 40:821-31.
8. Hagenäs L, Ritzen EM, Ploen L, Hansson V, French FS, Nayfeh SN. Sertoli cell origin of testicular androgen-binding protein (ABP). Mol Cell Endocrinol 1975; 2:339-350.
9. Danzo BJ, Cooper TG, Orgebin-Crist MC. Androgen binding protein (ABP) in fluids collected from the rete testis and cauda epididymidis of sexually mature and immature rabbits and observations on morphological changes in the epididymis following ligation of the ductuli efferentes. Biol Reprod 1977; 17:64-77.
10. Feldman M, Lea OA, Petrusz P, Tres LL, Kierszenbaum AL, French FS. Androgen-binding protein. Purification from rat epididymis, characterization and immunocytochemical localization. J Biol Chem 1981; 256:5170-5175.
11. French FS, Ritzén EM. A high-affinity androgen-binding protein (ABP) in rat testis: evidence for secretion into efferent duct fluid and absorption by epididymis. Endocrinology 1973; 93:88-95.
12. Gerard A, Khanfri J, Gueant JL, Fremont S, Nicolas JP, Grignon G, Gerard H. Electron microscope radioautographic evidence of in vivo androgen-binding protein internalization in the rat epididymis principal cells. Endocrinology 1988; 122:1297-1307.
13. Felden F, Leheup B, Fremont S, Bouguerne R, Egloff M, Nicolas JP, Grignon G, Gueant JL. The plasma membrane of epididymal epithelial cells has a specific receptor which binds to androgen-binding protein and sex steroid-binding protein. J Steroid Biochem Mol Biol 1992; 42:279-285.
14. Krupenko SA, Krupenko NI, Danzo BJ. Interaction of sex hormone-binding globulin with plasma membranes from the rat epididymis and other tissues. J Steroid Biochem Mol Biol 1994; 51:115-124.
15. Becker RR, Iles DJ. Developmental pattern of androgen-binding protein secretion during the critical period of sexual differentiation. Arch Androl 1985; 14:107-114.
16. Sullivan PM, Petrusz P, Szpirer C, Joseph DR. Alternative processing of androgen-binding protein RNA transcripts in fetal rat liver. Identification of a transcript formed by trans splicing. J Biol Chem 1991; 266:143-154.
17. Wang YM, Bayliss DA, Millhorn DE, Petrusz P, Joseph DR. The androgen-binding protein gene is expressed in male and female rat brain. Endocrinology 1990; 127:3124-3130.
18. Wang YM, Sullivan PM, Petrusz P, Yarbrough W, Joseph DR. The androgen-binding protein gene is expressed in CD1 mouse testis. Mol Cell Endocrinol 1989; 63:85-92.
19. Hammond GL. Potential functions of plasma steroid-binding proteins. Trends Endocrinol Metab 1995; 6:298-304.
20. Anthony CT, Danzo BJ, Orgebin-Crist MC. Investigations on the relationship between sperm fertilizing ability and the androgen binding protein in the restricted rat. Endocrinology 1984; 114:1413-1418.
21. Anthony CT, Danzo BJ, Orgebin-Crist MC. Investigations on the relationship between sperm fertilizing ability and the androgen binding protein in the hypophysectomized, pregnenolone-injected rat. Endocrinology 1984; 114:1419-1425.
22. Krupenko NI, Avvakumov GV, Strel'chyonok OA. Binding of sex hormone-binding globulin-androgen complexes to the placental syncytiotrophoblast membrane. Biochem Biophys Res Commun 1990; 171:1279-1283.
23. Frairia R, Fortunati N, Berta L, Fazzari A, Fissore F, Gaidano G. Sex steroid binding protein (SBP) receptors in estrogen sensitive tissues. J Steroid Biochem Mol Biol 1991; 40:805-812.
24. Hryb DJ, Khan MS, Romas NA, Rosner W. The solubilization and partial characterization of the sex hormone-binding globulin receptor from human prostate. J Biol Chem 1989; 264:5378-5383.
25. Fissore F, Fortunati N, Comba A, Fazzari A, Gaidano G, Berta L, Frairia R. The receptor-mediated action of sex steroid binding protein (SBP, SHBG): accumulation of cAMP in MCF7 cells under SBP and estradiol treatment. Steroids 1995; 59:661-667.
26. Nakhla AM, Khan MS, Rosner W. Biologically active steroids activate receptor-bound human sex hormone-binding globulin to cause LNCaP cells to accumulate adenosine 3′,5′-monophosphate. J Clin Endocrinol & Metab 1990; 71:398-404.
27. Nakhla AM, Khan MS, Romas NP, Rosner W. Estradiol causes the rapid accumulation of cAMP in human prostate. Proc Natl Acad Sci USA 1994; 91:5402-5405.
28. Sullivan PM, Wang YM, Joseph DR. Identification of an alternate promoter in the rat androgen-binding protein/sex hormone-binding globulin gene that regulates synthesis of a mRNA encoding a protein with altered function. Mol Endocrinol 1993; 7:702-715.
29. Joseph DR, Becchis M, Fenstermacher DA, Petrusz P. The alternate N-terminal sequence of rat androgen-binding protein/sex hormone-binding globulin contains a nuclear targeting signal. Endocrinology 1996; 137:1138-1143.
30. Reventos J, Sullivan PM, Joseph DR, Gordon JW. Tissue-specific expression of the rat androgen-binding protein/sex hormone-binding globulin gene in transgenic mice. Mol Cell Endocrinol 1993; 96:69-73.
31. Joseph DR, Power SGA, Petrusz P. Expression and distribution of androgen-binding protein/sex hormone-binding globulin in the female rodent reproductive system. Biol Reprod 1996; 55:14-20.
32. Wahl GM, Stern M, Stark GR. Efficient transfer of large DNA fragments from agarose gels to DBM-paper and rapid hybridization using dextran sulfate. Proc Natl Acad Sci USA 1979; 76:3683-3687.
33. Joseph DR, Hall SH, French FS. Rat androgen-binding protein: evidence for identical subunits and amino acid sequence homology with human sex hormone-binding globulin. Proc Natl Acad Sci USA 1987; 84:339-343.
34. Humason GL. Animal Tissue Techniques. 4th ed. San Francisco: W.H. Freeman and Co.; 1979.
35. Ordronneau P, Lindstrom PBM, Petrusz P. Four unlabeled antibody bridge techniques: a comparison. J Histochem Cytochem 1981; 29: 1397-1404.
36. Becchis M, Sullivan PM, Ordronneau P, Petrusz P, Joseph DR. Distribution of immunoreactive androgen-binding protein/sex hormone-binding globulin in tissues of the fetal rat. Steroids 1996; 61:392-400.
37. Ausubel FM, Brent R, Kingston RE. Current Protocols in Molecular Biology. New York: John Wiley & Sons; 1987: 10.8.1-6.
38. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond) 1970;227:680-685.
39. Kissinger C, Skinner MK, Griswold MD. Analysis of Sertoli cell-secreted proteins by two-dimensional gel electrophoresis. Biol Reprod 1982; 27:233-240.
40. Marshall T. Detection of proteins in polyacrylamide gels using an improved silver stain. Anal Biochem 1984; 136:340-346.
41. Joseph DR, Lawrence W, Danzo BJ. The role of asparagine-linked oligosaccharides in the subunit structure, steroid binding, and secretion of androgen-binding protein. Mol Endocrinol 1992; 6:1127-1134.
42. Bartke A, Steele RE, Musto NA, Caldwell BV. Fluctuations in plasma testosterone levels in adult male rats and mice. Endocrinology 1973; 92:1223-1228.
43. Danzo BJ, Bell BW. The microheterogeneity of androgen-binding protein in rat serum and epididymis is due to differences in glycosylation of their subunits. J Biol Chem 1988; 263:2402-2408.
44. Hamilton DW. The mammalian epididymis. In: Balin H, Glasser S (eds.), Reproductive Biology. Amsterdam: Excerpta Medica; 1972: 5-337.
45. Abou-Halla A, Fain-Maurel MA. Regional differences of the proximal part of mouse epididymis: morphological and histochemical. Anat Rec 1984; 209:197-208.
46. Ramos AS, Dym M. Fine structure of monkey epididymis. Am J Anat 1977; 149:501-532.
47. Larriba S, Esteban C, Toran N, Gerard A, Audi L, Gerard H, Reventos J. Androgen-binding protein is tissue-specifically expressed and biologically active in transgenic mice. J Steroid Biochem Mol Biol 1995; 53:573-578.
48. O'Donnell L, McLachlan RI, Wreford NG, Robertson DM. Testosterone promotes the conversion of round spermatids between stages VII and VIII of the rat spermatogenic cycle. Endocrinology 1994; 135: 2608-2614.
49. Sharpe RM, Maddocks S, Millar M, Kerr JB, Saunders PTK, McKinnell C. Testosterone and spermatogenesis. Identification of stage-specific, androgen-regulated proteins secreted by adult rat seminiferous tubules. J Androl 1992; 13:172-184.
50. Sun YT, Wreford NG, Robertson DM, de Kretser DM. Quantitative cytological studies of spermatogenesis in intact and hypophysectomized rats: identification of androgen-dependent stages. Endocrinology 1990; 127:1215-1223.
51. Raj HGM, Dym M. The effects of selective withdrawal of FSH or LH on spermatogenesis in the immature rat. Biol Reprod 1976; 14: 489-494.
52. Danzo BJ. The effects of a GnRH antagonist on androgen-binding protein distribution and other parameters in the adult male rat. Endocrinology 1995; 136:4004-4011.
53. Russell LD, Clermont Y. Degeneration of germ cells in normal, hypophysectomized and hormone treated hypophysectomized rats. Anat Rec 1977; 187:347-366.
54. McLachlan RI, Wreford NG, Meachem SJ, de Kretser DM, Robertson DM. Effects of testosterone on spermatogenic cell populations in the adult rat. Biol Reprod 1994; 51:945-955.
55. Henriksén K, Hakovirta H, Parvinen M. Testosterone inhibits and induces apoptosis in rat seminiferous tubules in a stage specific manner: in situ quantification in squash preparations after administration of ethane dimethane sulfonate. Endocrinology 1995; 136:3285-3291.
56. Billig H, Furuta I, Rivier C, Tapanainen J, Parvinen M, Hsueh AJW. Apoptosis in testis germ cells: developmental changes in gonadotropin dependence and localization to selective tubule stages. Endocrinology 1995; 136:5-12.
57. Bartke A. Editorial: apoptosis of male germ cells, a generalized or cell type-specific phenomenon? Endocrinology 1995; 136:3-4.