Allogeneic dendritic cell induction of HIV-specific cytotoxic T lymphocyte responses from T cells of HIV type 1-infected and uninfected individuals

AIDS Research and Human Retroviruses

Volumn 13, Issue 1, 1997, Pages 33-39

  Dupuis, Marc ^a   Peshwa, Madhusudan V ^b   Benike, Claudia ^c   Kundu, Smriti K ^a   Engleman, Edgar G ^c   Van Schooten, Wim C A ^b   Merigan, Thomas C ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Activated Cell Therapy   (United States)

^c STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS VACCINE;

ARTICLE; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOSTIMULATION; PRIORITY JOURNAL;

EID: 0031020905     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.1997.13.33     Document Type: Article

References (36)

1. Koup RA, Safrit JT, Cao Y, Andrews CA, McLeod G, Borkowsky W, Farthing C, and Ho DD: Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J Virol 1994;68:4650-4655.
2. Borrow P, Lewicki H, Hahn B, Shaw GM, and Oldstone MBA: Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J Virol 1994;68:6103-6110.
3. Walker BD, Chakrabarti S, Moss B, Paradis TJ, Flynn T, Durno AG, Blumberg RS, Kaplan JC, Hirsch MS, and Schooley RT: HIV-specific cytotoxic T lymphocytes in seropositive individuals. Nature (London) 1987;328:345-348.
4. Koenig S, Earl P, Powell D, Pantaleo G, Merli S, Moss B, and Fauci AS: Group-specific, major histocompatibility complex class I-restricted cytotoxic responses to human immunodeficiency virus 1 (HIV-1) envelope proteins by cloned peripheral blood T cells from an HIV-1-infected individual. Proc Natl Acad Sci USA 1988;85:8638-8642.
5. Koup RA, Sullivan JL, Levine PH, Brettler D, Mahr A, Mazzara G, McKenzie S, and Panicali D: Detection of major histocompatibility complex class I-restricted, HIV-specific cytotoxic T lymphocytes in the blood of infected hemophiliacs. Blood 1989;73:1909-1914.
6. Carmichael A, Jin X, Sissons P, and Borysiewicz L: Quantitative analysis of the human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocyte (CTL) response at different stages of HIV-1 infection: Differential CTL responses to HIV-1 and Epstein-Barr virus in late disease. J Exp Med 1993;177:249-256.
7. Koenig S, Conley AJ, Brewah YA, Jones GM, Leath S, Boots LJ, Davey V, Pantaleo G, Demarest JF, Carter C, Wannebo C, Yannelli JR, Rosenberg SA, and Lane HC: Transfer of HIV-1-specific cytotoxic T lymphocytes to an AIDS patient leads to selection for mutant HIV variants and subsequent disease progression. Nature Med 1995;1:330-336.
8. Hoffenbach A, Langlade-Demoyen P, Dadaglio G, Vilmer E, Michel F, Mayaud C, Autran B, and Plata F: Unusually high frequencies of HIV-specific cytotoxic T lymphocytes in humans. J Immunol 1989;142:452-462.
9. Moss PAH, Rowland-Jones SL, Frodsham PM, McAdam S, Giangrand P, McMichael AJ, and Bell JI: Persistent high frequency of human immunodeficiency virus-specific cytotoxic T cells in peripheral blood of infected donors. Proc Natl Acad Sci USA 1995;92:5773-5777.
10. McMichael AJ and Walker BD. Cytotoxic T lymphocyte epitopes: Implications for HIV vaccines. AIDS 1994;8(Suppl. 1):155-173.
11. Phillips RE, Rowland-Jones S, Nixon DF, Gotch FM, Edwards JP, Ogunlesi AO, Elvin JG, Rothbard JA, Bangham CRM, Rizza CR, and McMichael AJ: Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition. Nature (London) 1991;354:453-459.
12. Couillin I, Culmann-Penciolelli B, Gomard E, Choppin J, Levy J-P, Guillet J-G, and Saragosti S: Impaired cytotoxic T lymphocyte recognition due to genetic variations in the main immunogenic region of the human immunodeficiency virus 1 NEF protein. J Exp Med 1994;180:1129-1134.
13. + cytotoxic T lymphocytes by dendritic cells. J Exp Med 1987;166:182-194.
14. Macatonia SE, Taylor PM, Knight SC, and Askonas BA: Primary stimulation by dendritic cells induces antiviral proliferative and cytotoxic T cell responses in vitro. J Exp Med 1988;169:1255-1254.
15. Mehta-Demani A, Markowicz S, and Engleman EG: Generation of antigen-specific CD8+ CTLs from naive precursors. J Immunol 1994;153:996-1003.
16. Inaba K, Metlay JP, Crowley MT, and Steinman RM: Dendritic cells pulsed with protein antigens in vitro can prime antigen-specific, MHC-restricted T cells in situ. J Exp Med 1990;172:631-640.
17. Caux C, Liu Y-J, and Banchereau J: Recent advances in the study of dendritic cells and follicular dendritic cells. Immunol Today 1995;16:2-4.
18. Romani N, Gruner S, Brang D, Kampgen E, Lenz A, Trockenbacher B, Konwalinka G, Fritsch PO, Steinman RM, and Schuler G: Proliferating dendritic cell progenitors in human blood. J Exp Med 1994;180:83-93.
19. Grabbe S, Beissert S, Schwartz T, and Granstein RD: Dendritic cells as initiators of tumor immune responses: A possible strategy for tumor immunotherapy? Immunol Today 1995;16:116-120.
20. Takahashi H, Nakagawa Y, Yokomuro K, and Berzofsky JA: Induction of CD8+ cytotoxic T lymphocytes by immunization with syngeneic irradiated HIV-1 envelope derived peptide-pulsed dendritic cells. Int Immunol 1993;35:849-857.
21. Mayordomo JI, Zorina T, Storkus WJ, Zitvogel L, Celuzzi C, Falo LD, Melief CJ, Ildstad ST, Kast WM, Deleo AB, and Lotze MT: Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumor immunity. Nature Med 1995;1:1297-1302.
22. Hsu FJ, Benike C, Fagnoni F, Liles TM, Czerwinski D, Taidi B, Engleman EG, and Levy R: Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nature Med 1996;2:52-58.
23. Macatonia SE, Lau R, Patterson S, Pinching AJ, and Knight SC: Dendritic cell infection, depletion, and dysfunction in HIV-infected individuals. Immunology 1990;71:38-45.
24. Knight SC: Mechanisms of retravirally induced immunosuppression acting via dendritic cells. Adv Exp Med Biol 1995;378:423-427.
25. Roederer M, Dubs JG, Anderson MT, Raju PA, and Herzenberg LA: CD8 naive T cells counts decrease progressively in HIV-infected adults. J Clin Invest 1995;95:2061-2066.
26. Dupuis M, Kundu SK, and Merigan TC: Characterization of HLA-A*0201-restricted cytotoxic T cell epitopes in conserved regions of the HIV type 1 gp160 protein. J Immunol 1995;155:2232-2239.
27. Gumperz JE, Litwin V, Phillips JH, Lanier LL, and Parham P: The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor. J Exp Med 1995;181:1133-1144.
28. Dai LC, West K, Littaua R, Takahashi K, and Ennis FA: Mutation of human immunodeficiency virus type 1 at amino acid 585 on gp41 results in loss of killing by CD8+ A24-restricted cytotoxic T lymphocytes. J Virol 1992;66:3151-3154.
29. Fauci AS: Multifactorial nature of human immunodeficiency virus disease: Implications for therapy. Science 1993;262:1011-1018.
30. Cease KB and Berzofsky JA: Towards a vaccine for AIDS: The emergence of immunobiology-based vaccine development. Annu Rev Immunol 1994;12:923-989.
31. van der Burg SH, Klein MR, van de Velde CJH, Kast WM, Miedema F, and Melief CJM: Induction of a primary human cytotoxic T-lymphocyte response against a novel conserved epitope in a functional sequence of HIV-1 reverse transcriptase. AIDS 1995;9:121-127.
32. Walker BD, Flexner C, Birch-Limberger K, Fischer L, Paradis TJ, Aldovini A, Young R, Moss B, and Schooley RT: Long-term culture and fine specificity of human cytotoxic T-lymphocyte clones reactive with human immunodeficiency virus type 1. Proc Natl Acad Sci USA 1989;86:9514-9518.
33. Johnson RP, Trocha A, Yang L, Mazzara GP, Panicali DL, Buchanan TM, and Walker BD: HIV-1 Gag-specific cytotoxic T lymphocytes recognize multiple highly conserved epitopes. J Immunol 1991;147:1512-1521.
34. Pope M, Betjes MGH, Romani N, Hirmand H, Cameron PU, Hoffman L, Gezelter S, Schuler G, and Steinman RM: Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1. Cell 1994;78:389-398.
35. Borrow P, Evans CF, and Oldstone MBA: Virus-induced immunosuppression: Immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression J Virol 1995;69:1059-1070.
36. Pantaleo G, Graziosi C, Demarest JF, Butini L, Montroni M, Fox CH, Orenstein JM, Kotler DP, and Fauci AS: HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature (London) 1993;362:355-358.