Effects of prenatal cocaine exposure on the developing hippocampus: Intrinsic and synaptic physiology

Journal of Neurophysiology

Volumn 77, Issue 1, 1997, Pages 126-136

  Baraban, Scott C ^a   Schwartzkroin, Philip A ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COCAINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN SLICE; CONTROLLED STUDY; DENTATE GYRUS; ELECTROPHYSIOLOGY; FEMALE; HIPPOCAMPUS; INHIBITORY POSTSYNAPTIC POTENTIAL; MEMBRANE POTENTIAL; NONHUMAN; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT;

EID: 0031020619     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1997.77.1.126     Document Type: Article

References (85)

1. ADAMS, P. R. AND BROWN, D. A. Synaptic inhibition of the M-current: slow excitatory post-synaptic potential mechanism in bullfrog sympathetic neurones. J. Neurophysiol. 332: 263-272, 1982.
2. AGHAJANIAN, G. K. AND RASMUSSEN, K. Intracellular studies in the facial nucleus illustrating a simple new method for obtaining viable motoneurons in adult rat brain slices. Synapse 3: 331-338, 1989.
3. AKBARI, H. M. AND AZMITIA, E. C. Increased tyrosine hydroxylase immunoreactivity in the rat cortex following cocaine exposure. Dev. Brain Res. 66: 277-281, 1992.
4. 1A receptor agonist. Neurosci. Lett. 170: 141-144, 1994.
5. ALGER, B. E. AND NICOLL, R. A. Pharmacological evidence for two kinds of GABA receptors on rat hippocampal pyramidal cells studied in vitro. J. Physiol. Lond. 328: 125-141, 1982.
6. ANDAY, E. K., COHEN, M. E., KELLEY, N. E., AND LEITNER, D. S. Effect of in utero cocaine exposure on startle and its modification. Dev. Pharmacol. Ther. 12: 137-145, 1989.
7. ANDERSON-BROWN, T., SLOTKIN, T. A., AND SEIDLER, F. J. Cocaine acutely inhibits DNA synthesis in developing rat brain regions: evidence for direct actions. Brain Res. 537: 197-202, 1990.
8. BARABAN, S. C. AND SCHWARTZKROIN, P. A. Electrophysiology of CA1 pyramidal neurons in an animal model of neuronal migration disorders: prenatal methylazoxymethanol treatment. Epilepsy Res. 22: 145-156, 1995.
9. BENARDO, L. S. AND PRINCE, D. A. Ionic mechanisms of cholinergic excitation in mammalian hippocampal pyramidal cells. Brain Res. 249: 333-344, 1982.
10. BINGOL, N., FUCHS, M., DIAZ, V., STONE, R. K., AND GROMISCH, D. S. Teratogenicity of cocaine in humans. J. Pediatr. 110: 93-96, 1987.
11. BROWN, E. R., COLE, J., PARKERS, S., COULTER, D., CORWIN, M., AND ABOAGYNE, K. Effect of prenatal cocaine exposure on EEG activity of narcotic-addicted infants (Abstract). Pediatr. Res. 25: 353, 1989.
12. BUCKMASTER, P. S., STROWBRIDGE, B. W., AND SCHWARTZKROIN, P. A. A comparison of rat hippocampal mossy cells and CA3c pyramidal cells. J. Neurophysiol. 70: 1281-1299, 1993.
13. BURCHFIELD, D. AND ABRAMS, R. Cocaine depresses cerebral glucose utilization in fetal sheep. Dev. Brain Res. 73: 283-288, 1993.
14. CHASNOFF, I. J. Effects of maternal narcotic vs. nonnarcotic addiction on neonatal neurobehavior and infant development. Natl. Inst. Drug Abuse Res. Monogr. 59: 73-83, 1985.
15. CHASNOFF, I. J., LANDRESS, H. J., AND BARRETT, M. E. The prevalence of illicit-drug or alcohol use during pregnancy and discrepancies in mandatory reporting in Pinellas county, Florida. New Engl. J. Med. 322: 1202-1206, 1990.
16. CHERUKI, R., MINKOFF, H., FELDMAN, J., PAREKH, A., AND GLASS, L. A cohort study of alkaloidal cocaine ("crack") in pregnancy. Obstet. Gynecol. 72: 147-151, 1988.
17. CHURCH, M. W., DINTCHEFF, B. A., AND GESSNER, P. K. Dose-dependent consequences of cocaine on pregnancy outcome in the Long-Evans rat. Neurotoxicol. Teratol. 10: 51-58, 1987.
18. CHURCH, M. W., OVERBECK, G. W., AND ANDRZEJCZAK, A. L. Prenatal cocaine exposure in the Long-Evans rat. I. Dose-dependent effects on gestation, mortality, and postnatal maturation. Neurotoxicol. Teratol. 12: 327-334, 1990.
19. COLES, C. D., PLATZMAN, K. A., SMITH, I., JAMES, M. E., AND FALEK, A. Effects of cocaine and alcohol use in pregnancy on neonatal growth and neurobehavioral status. Neurotoxicol. Teratol. 14: 23-33, 1992.
20. B receptor-mediated responses in neocortex of rat and cat. J. Physiol. Lond. 406: 443-468, 1988.
21. DAILEY, J. W., MISHRA, P. K., KO, K. H., PENNY, J. E., AND JOBE, P. C. Noradrenergic abnormalities in the central nervous system of seizurenaive genetically epilepsy-prone rats. Epilepsia 32: 168-173, 1991.
22. DEVANE, C. L., SIMPKINS, J. W., MILLER, R. L., AND BRAUN, S. B. Tissue distribution of cocaine in the pregnant rat. Life Sci. 45: 1271-1276, 1989.
23. DHUNA, A., PASCUAL-LEONE, A., LANGENDORF, F., AND ANDERSON, D. C. Epileptogenic properties of cocaine in humans. Neurotoxicology 12: 621-626, 1991.
24. DIXON, S. D. AND BEJAR, R. Echoencephalographic findings in neonates associated with maternal cocaine and metamphetamine use: incidence and clinical correlates. J. Pediatr. 115: 770-778, 1989.
25. DOW-EDWARDS, D. L. Long-term neurochemical and neurobehavioral consequences of cocaine use during pregnancy. Ann. NY Acad. Sci. 562: 280-289, 1989.
26. DOW-EDWARDS, D. L., FICO, T. A., AND HUTCHINGS, D. E. Functional effects of cocaine given during critical periods of development. Teratology 37: 518-525, 1988.
27. DOW-EDWARDS, D. L., FREED, L. A., AND FICO, T. A. Structural and functional effects of prenatal cocaine exposure in adult rat brain. Dev. Brain Res. 57: 263-268, 1990.
28. DOWNS, A. W. AND EDDY, N. B. The effect of repeated doses of cocaine on the rat. J. Pharmacol Exp. Ther. 46: 199-200, 1932.
29. ELLIS, J. E., BYRD, L. D., SEXSON, W. R., AND PATTERSON-BARNETT, C. A. In utero exposure to cocaine: a review. South. Med. J. 86: 725-731, 1993.
30. EYLER, F. D., BEHNKE, M., CONLON, M., WOODS, N. S., AND FRENTZEN, B. Prenatal cocaine use: a comparison of neonates matched on maternal risk factors. Neurotoxicol. Teratol. 16: 81-87, 1994.
31. FAINGOLD, C. L. The genetically epilepsy-prone rat. Gen. Pharmacol. 19: 331-338, 1988.
32. FRANCK, J. E., GINTER, K. L., AND SCHWARTZKROIN, P. A. Developing genetically epilepsy-prone rats have an abnormal seizure response to flurothyl. Epilepsia 30: 1-6, 1989.
33. GOMEZ-ANSON, B. AND RAMSEY, R. G. Pachygyria in a neonate with prenatal cocaine exposure: MR features. J. Comput, Assisted Tomogr. 18: 637-639, 1994.
34. GRESSENS, P., GOFFLOT, F., VAN-MAELE-FABRY, G., MISSON, J., GADISEUX, J., EVRARD, P., AND PICARD, J. J. Early neurogenesis and teratogenesis in whole mouse embryo cultures. Histochemical, immunocytochemical and ultrastructural study of premigratory neuronal-glial units in normal mouse embryo and mouse embryos influenced by cocaine and retinoic acid. J. Neuropathol Exp. Neurol. 51: 206-219, 1992a.
35. GRESSENS, P., KOSOFSKY, B. E., AND EVRARD, P. Cocaine-induced disturbances of corticogenesis in the developing murine brain. Neurosci. Lett. 140: 113-116, 1992b.
36. GUSTAFSSON, B. AND WIGSTROM, H. Evidence for two types of afterhyperpolarization in CA1 pyramidal cells in the hippocampus. Brain Res. 206: 462-468, 1981.
37. HAAS, H. L. 41ND KONNERTH, A. Histamine and noradrenaline decrease calcium-activated potassium conductance in hippocampal pyramidal cells. Nature Lond. 302: 432-434, 1983.
38. HORN, J. P. AND McAFEE, D. A. Alpha-adrenergic inhibition of calciumdependent potentials in rat sympathetic neurones. J. Neurophysiol. 301: 191-204, 1980.
39. HOTSON, J. R. AND PRINCE, D. A. A calcium-activated hyperpolarization follows repetitive firing in hippocampal neurons. J. Neurophysiol 42: 889-895, 1980.
40. JOBE, P. C. AND LAIRD, H. E. Neurotransmitter abnormalities as determinants of seizure susceptibility and intensity in the genetic models of epilepsy. Biochem. Pharmacol 30: 3137-3144, 1991.
41. KALLYANPUR, S. G. AND RYMAN, B. E. Some effects of local anesthetics on cell metabolism. Biochem. Pharmacol 15: 691-701, 1966.
42. KAPUR, R. P., SHAW, C. M., AND SHEPARD, T. H. Brain hemorrhages in cocaine-exposed human fetuses. Teratology 44: 11-18, 1991.
43. KLIEGMAN, R. M., MADURA, D., KIWI, R., EISENBERG, I., AND YAMASHITA, T. Relation of maternal cocaine use to the risks of prematurity and low birth weight. J. Pediatr. 124: 751-756, 1994.
44. KOSOFSKY, B. E., WILKINS, A. S., GRESSENS, P., AND EVRARD, P. Transplacental cocaine exposure: a mouse model demonstrating neuroanatomic and behavioral abnormalities. J. Child Neurol. 9: 234-241, 1994.
45. KRAMER, L. D., LOCKE, G. E., OGUNYEMI, A., AND NELSON, L. Neonatal cocaine-related seizures. J. Child Neurol. 5: 60-64, 1990.
46. KREISMAN, N. R. 41ND SMITH, M. L. Potassium-induced changes in excitability in the hippocampal CA1 region of immature and adult rats. Dev. Brain Res. 76: 67-73, 1993.
47. LAIRD, H. E., DAILEY, J. W., AND JOBE, P. C. Neurotransmitter abnormalities in genetically epileptic rodents. Federation Proc. 43: 2505-2509, 1984.
48. LANCASTER, B. AND ADAMS, P. R. Calcium-dependent current generating the afterhyperpolarization of hippocampal neurons. J. Neurophysiol 55: 1268-1282, 1986.
49. LEGIDO, A., CLANCY, R. R., SPITZER, A. R., AND FINNEGAN, L. P. Electroen-cephalographic and behavioral-state studies in infants of cocaine-addicted mothers. Am. J. Dis. Child. 146: 748-752, 1992.
50. LORENZON, N. M. AND FOEHRING, R. C. Alterations in intracellular calcium chelation produce developmental differences in repetitive firing and after-hyperpolarizations in rat neocortical neurons. Dev. Brain Res. 84: 192-203, 1995.
51. LUHMANN, H. J., MlTTMAN, T., VAN LUIJELAAR, G., AND HEINEMANN, U. Impairment of intracortical GABAergic inhibition in a rat model of absence epilepsy. Epilepsy Res. 22: 43-51, 1995.
52. MADISON, D. V. AND NICOLL, R. A. Noradrenaline blocks accommodation of pyramidal cell discharge in the hippocampus. Nature Lond. 299: 636-638, 1982.
53. MADISON, D. V. AND NICOLL, R.A. Control of the repetitive discharge of rat CA1 pyramidal neurons in vitro. J. Physiol. Lond. 354: 319-331, 1984.
54. MANGAN, P. S., REMPE, D. A., AND LOTHMAN, E. W. Changes in inhibitory neurotransmission in the CA1 region and dentate gyrus in a chronic model of temporal lobe epilepsy. J. Neurophysiol. 74: 829-840, 1995.
55. McCORMICK, D. A. GABA as an inhibitory neurotransmitter in human cerebral cortex. J. Neurophysiol. 62: 1018-1027, 1989.
56. MILLER, M. W., WAZIRI, R., BARUAH, S., AND GILLIAM, D. M. Long-term consequences of prenatal cocaine exposure on biogenic amines in the brain of mice: the role of sex. Dev. Brain Res. 87: 22-28, 1995.
57. MIROCHNIK, M., MEYER, J., COLE, J., HERREN, T., AND ZUCKERMAN, B. Circulating catecholamine concentrations in cocaine-exposed neonates: a pilot study. Pediatrics 88: 481-485, 1991.
58. MOSHE, S. L. Epileptogenesis and the immature brain. Epilepsia 28, Suppl. 1: 3-15, 1987.
59. MOSHE, S. L. Seizures in the developing brain. Neurology 93, Suppl. 5: 3-7, 1993.
60. MYERS, J. A. AND EARNEST, M. P. Generalized seizures and cocaine abuse. Neurology 34: 675-676, 1984.
61. NASSOGNE, M.-C., EVRARD, P., AND COURTOY, P. J. Selective neuronal toxicity of cocaine in embryonic mouse brain cocultures. Proc. Natl. Acad. Sci. USA 92: 11029-11033, 1995.
62. B receptors play a major role in paired-pulse facilitation in area CA1 of the rat hippocampus. Brain Res. 531: 55-65, 1990.
63. NEWBERRY, N. R. AND NICOLL, R. A. A bicuculline-resistant inhibitory postsynaptic potential in rat hippocampal pyramidal cells in vitro. J. Physiol. Lond. 348: 239-254, 1984.
64. OSTREA, E. M., BRADY, M., GAUSE, S., RAYMUNDO, A. L., AND STEVENS, M, Drug screening of newborns by meconium analysis: a large scale, prospective, epidemiologic study. Pediatrics 89: 107-113, 1992.
65. REIGEL, C. E., DAILEY, J. W., AND JOBE, P. C. The genetically epilepsy-prone rat: an overview of seizure-prone characteristics and responsiveness to anticonvulsant drugs. Life Sci. 39: 763-774, 1986.
66. REMPE, D. A., MANGAN, P., AND LOTHMAN, E. W. Regional heterogeneity of pathyophysiological alterations in CA1 and dentate gyrus in a chronic model of temporal lobe epilepsy. J. Neurophysiol. 74: 816-828, 1995.
67. ROYALL, G. D. AND SMITH, R. F. Prenatal cocaine alters hippocampal morphology in the rat (Abstract). Teratology 45: 530, 1992.
68. SAH, P. AND ISAACSON, J. S. Channels underlying the slow afterhyperpolarization in hippocampal pyramidal neurons: neurotransmitters modulate the open probability. Neuron 15: 435-441, 1995.
69. SCHWARTZKROIN, P. A. Development of rabbit hippocampus: physiology. Dev. Brain Res. 2: 469-486, 1982.
70. SCHWARTZKROIN, P. A., MOSHE, S. L., NOEBELS, J. L., AND SWANN, J. W. Brain Development and Epilepsy. New York: Oxford Univ. Press, 1995.
71. SEIDLER, F. J. AND SLOTKIN, T. A. Fetal exposure causes persistent nonadrenergic hyperactivity in rat brain regions: effects on neurotransmitter turnover and receptors. J. Pharmacol. Exp. Ther. 263: 413-421, 1992.
72. SEIDLER, F. J., TEMPLE, S. W., McCooK, E. C., AND SLOTKIN, T. A. Cocaine inhibits central noradrenergic and dopaminergic activity during the critical developmental period in which catecholamines influence cell development. Dev. Brain Res. 85: 48-53, 1995.
73. SINGER, L., ARENDT, R., AND MINNES, S. Neurodevelopmental effects of cocaine, Clin. Perinatol. 20: 245-262, 1993.
74. SNYDER-KELLER, A. AND KELLER, R. W., JR. Prenatal cocaine alters later sensitivity to cocaine-induced seizures. Neurosci. Lett. 191: 149-152, 1995.
75. SPEAR, L. P., KIRSTEIN, C. L., AND FRAMBES, N. A. Cocaine effects on the developing central nervous system: behavioral, psychopharmacological, and neurochemical studies. Ann. NY Acad. Sci. 562: 290-307, 1989.
76. 2 receptor sites and mRNA levels in the offspring. Mol. Neurobiol. 11: 67-76, 1995.
77. STORM, J. F. Action potential repolarization and a fast after-hyperpolarization in rat hippocampal pyramidal cells. J. Physiol. Lond. 385: 733-759, 1987.
78. STORM, J. F. Potassium currents in hippocampal pyramidal cells. Prog. Brain Res. 83: 161-187, 1990.
79. THADANI, P. V. Biological mechanisms and perinatal exposure to abused drugs. Synapse 19: 228-232, 1995.
80. TSAY, C. H., PARTRIDGE, C., VILLARREAL, S. F., GOOD, W. V., AND FERRIERO, M. D. Neurologic and opthalmologic findings in children exposed to cocaine in utero. J. Child Neurol. 11: 25-30, 1996.
81. TYLER, R., CHUGANI, H., AND HOWARD, J. A pilot study of cerebral glucose utilization in children with prenatal drug exposure (Abstract). Ann. Neurol. 34: 460, 1993.
82. VERMA-AHUJA, S., EVANS, M. S., AND PENCEK, T. L. Evidence for decreased potassium conductance in hippocampal CA3 neurons of genetiically epilepsy prone rats. Epilepsy Res. 22: 137-144, 1995.
83. VERMA-AHUJA, S. AND PENCEK, T. L. Hippocampal CA1 neuronal properties in genetically epilepsy-prone rats: evidence for increased excitation. Epilepsy Res. 18: 205-215, 1994.
84. VIANA, F., BAYUSS, D. A., AND BERGER, A. J. Calcium conductances and their role in the firing behavior of neonatal hypoglossal motoneurons. J. Neurophysiol. 69: 2137-2149, 1993.
85. XAVIER, M. R., TAVARES, M. A., MACHADO, J. D., SILVA-ARAUJO, A., AND SILVA, M. C. Effects of prenatal cocaine exposure in the prefrontal cortex of the rat. Mol. Neurobiol. 11: 95-110, 1995.