Increasing or decreasing nervous activity modulates the severity of the glio-vascular lesions of 1,3-dinitrobenzene in the rat: Effects of the tremorgenic pyrethroid, Bifenthrin, and of anaesthesia

Acta Neuropathologica

Volumn 93, Issue 2, 1997, Pages 159-165

  Holton, J L ^a,c   Nolan, C C ^a   Burr, S A ^a   Ray, D E ^a   Cavanagh, J B ^b  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

1,3 dinitrobenzene; Bifenthrin tremor; Energy deprivation syndromes; Modulation of glio vascular lesions; Neurotoxicity

Indexed keywords

1,3 DINITROBENZENE; BIFENTHRIN; ISOFLURANE; PYRETHROID; UNCLASSIFIED DRUG; URETHAN;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA; BRAIN STEM; CELL ACTIVITY; CONTROLLED STUDY; DISEASE SEVERITY; FACIAL NERVE NUCLEUS; GLIA; MALE; MAMMILLARY BODY; MOTONEURON NUCLEUS; NERVE CELL; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SUBTHALAMIC NUCLEUS; TREMOR; TRIGEMINAL NERVE;

EID: 0031019899     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010050597     Document Type: Article

References (18)

1. Cavanagh JB (1993) Selective vulnerability in acute energy deprivation syndromes, Neuropathol Appl Neurobiol 19:461-470
2. Cavanagh JB, Nolan CC (1993) The neurotoxicity of α-chlorohydrin in rats and mice. II. Lesion topography and factors in selective vulnerability in acute energy deprivation syndromes. Neuropathol Appl Neurobiol 19:471-479
3. Cremer JE, Cunningham VJ, Ray DE, Sarna GS (1980) Regional changes in brain glucose utilisation in rats given a pyrethroid insecticide. Brain Res 194:278-282
4. Forshaw PJ, Ray DE (1986) The effects of two pyrethroids, cismethrin and deltamethrin, on skeletal muscle and the trigeminal reflex. Pesticide Biochem Physiol 25:143-151
5. Hakim AM, Pappius HM (1981) The effect of thiamine deficiency on local cerebral glucose utilization. Ann Neurol 9:334-339
6. Moore LE, Kirsch JR, Helfaer MA, Tobin JR, McPherson RW, Traystman RJ (1994) Nitric oxide and prostanoids contribute to isoflurane-induced hyperaemia in pigs. Anesthesiology 80: 1328-1337
7. Narahashi T (1974) Chemicals as tools in the study of excitable membranes. Physiol Rev 54: 813-889
8. + channels as targets of insecticides. Trends Pharmacol Sci 13:236-241
9. Philbert MA, Nolan CC, Cremer JE, Tucker D, Brown AW (1987) 1,3-Dinitrobenzene-induced encephalopathy in rats. Neuropathol Appl Neurobiol 13:371-389
10. Ray DE (1980) An EEG investigation of decamethrin induced choreoathetosis in the rat. Exp Brain Res 38:221-227
11. Ray DE (1982) Changes in brain blood flow associated with deltamethrin induced choreoathetosis in the rat. Exp Brain Res 45:269-276
12. Ray DE (1991 ) Pesticides derived from plants and other organisms. In: Hayes WJ, Lawes ER (eds) Handbook of pesticide toxicology. Academic Press, Londong, pp 585-636
13. Ray DE, Brown AW, Cavanagh JB, Nolan CC, Richards HK, Wylie SP (1992) Functional/metablic modulation of the brain stem lesions caused by 1,3-dinitrobenzene in the rat. Neurotoxicology 13:379-388
14. Ray DE, Holton JL, Lister T, Nolan CC (1995) The glio-vascular toxicity of m-dinitrobenzene and related agents: modulation of toxicity by neuronal activation. Arch Toxicol 18 [Suppl]:140-148
15. Romero L, Brown AW, Cavanagh JB, Nolan CC, Ray DE, Seville MP (1991) Vascular factors in the neurotoxic damage caused by 1,3-dinitrobenzene in the rat. Neuropathol Appl Neurobiol 17:495-508
16. 14C] deoxyglucose method for the localization of cerebral glucose utilization: theory, procedure and normal values in the conscious and anaesthetised rat. J Neurochem 28:897-916
17. Vijverberg HPM, Bercken J van den (1974) Frequency dependant effects of the pyrethroid insecticide decamethrin in frog myelinated nerve fibres. Eur J Pharmacol 58:501-504
18. Vijverberg HPM, Bercken J van den (1982) Action of pyrethroid insecticides on the vertebrate nervous system Neuropathol Appl Neurobiol 8:421-440