Lansoprazole and ranitidine affect the accuracy of the 14C-urea breath test by a pH-dependent mechanism

American Journal of Gastroenterology

Volumn 92, Issue 3, 1997, Pages 446-450

  Chey, W D ^a,b   Woods, M ^a   Scheiman, J M ^a   Nostrant, T T ^a   DelValle, J ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b Box 0362 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON 14; LANSOPRAZOLE; RANITIDINE; UREA;

ADULT; ARTICLE; BREATH ANALYSIS; CLINICAL ARTICLE; FEMALE; GRAM NEGATIVE INFECTION; HELICOBACTER PYLORI; HUMAN; MALE; PATIENT MONITORING; PRIORITY JOURNAL; STOMACH ACID SECRETION; STOMACH PH;

2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES; ANTI-BACTERIAL AGENTS; ANTI-ULCER AGENTS; BREATH TESTS; CARBON DIOXIDE; CARBON RADIOISOTOPES; FALSE NEGATIVE REACTIONS; FEMALE; FORECASTING; GASTRIC ACID; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HISTAMINE H2 ANTAGONISTS; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MIDDLE AGED; MONITORING, AMBULATORY; OMEPRAZOLE; RANITIDINE; STOMACH; UREA;

EID: 0031019553     PISSN: 00029270     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Hopkins RJ, Girardi LS, Turney EA. Relationship between Helicobacter pylori eradication and reduced duodenal and gastric ulcer recurrence: A review. Gastroenterology 1996;110:1244-52.
2. Marshall B. Helicobacter pylori. Am J Gastroenterol 1994;89:S116-28.
3. Brown KE, Peura DA. Diagnosis of Helicobacter pylori infection. Gastroenterol Clin North Am 1993;22:105-15.
4. Atherton JC, Spiller RC. The urea breath test for Helicobacter pylori. Gut 1994;35:723-5.
5. 14C-urea breath test offers diagnosis of Helicobacter pylori in 10 minutes. Am J Gastroenterol 1996;91:233-8.
6. 14C-urea breath test. Am J Gastroenterol 1996;91:89-92.
7. Iwahi T, Satoh H, Nakao M, et al. Lansoprazole, a novel benzimidazole proton pump inhibitor, and its related compounds have selective activity against Helicobacter pylori. Antimicrob Agents Chemother 1991;35:490-6.
8. Barradell LB, Faulds D, McTavish D. Lansoprazole: A review of its pharmacodynamic and pharmacokinetic properties and its therapeutic efficacy in acid-related disorders. Drugs 1992;44:225-50.
9. McGowan C, Cover T, Blaser M. The proton pump inhibitor omeprazole inhibits acid survival of Helicobacter pylori by a urea-independent mechanism. Gastroenterology 1994;107:738-43.
10. Jhala NC, McFarland MM, Brightman SA, et al. The effects of short-term lansoprazole therapy on Helicobacter pylori infection and antral gastritis in duodenal ulcer patients. Am J Gastroenterol 1995;90: 1824-8.
11. Nagata K, Takogi E, Tsunda M, et al. Inhibitory action of lansoprazole and its analogs against Helicobacter pylori: Inhibition of growth is not related to inhibition of urease. Antimicrob Agents Chemother 1995; 39:567-70.
12. Nagata K, Satoh H, Iwahi T, et al. Potent inhibitory action of the gastric proton pump inhibitor lansoprazole against urease activity of Helicobacter pylori: Unique action selective for H. pylori cells. Antimicrob Agents Chemother 1993;37:769-74.
13. Clyne M, Labigne A, Drumm B. Helicobacter pylori requires an acidic environment to survive in the presence of urea. Infect Immun 1995; 63:1669-73.
14. McGowan CC, Cover TL, Blaser MJ. Helicobacter pylori and gastric acid: Biological and therapeutic implications. Gastroenterology 1996; 110:926-38.
15. Stockbreugger RW. Bacterial overgrowth as a consequence of reduced gastric acidity. Scand J Gastroenterol 1985;111:7-16.
16. Sharma BK, Santana IA, Wood EC, et al. Intragastric bacterial activity and nitrosation before, during, and after treatment with omeprazole. Br Med J 1984;289:717-9.
17. Han SW, Evans DG, El-Zaatari FAK, et al. The interaction of pH, bile, and Helicobacter pylori may explain duodenal ulcer. Am J Gastroenterol 1996;91:1135-7.
18. 14C-urea breath test repeated after 1 week. Am J Gastroenterol 1995;90:2103-5.