Substrate properties of C'-methyl UTP derivatives in T7 RNA polymerase reactions. Evidence for N-type NTP conformation

FEBS Letters

Volumn 400, Issue 3, 1997, Pages 263-266

  Tunitskaya, V L ^a   Rusakova, E E ^a   Padyukova, N Sh ^a   Ermolinsky, B S ^a   Chernyi, A A ^a   Kochetkov, S N ^a   Lysov, Yu P ^a   Mikhailov, S N ^a  

^a ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

Author keywords

C' methyl analogue of UTP; Conformational energy calculation; RNA chain terminator; Substrate conformation; T7 RNA polymerase; Transcription

Indexed keywords

RNA POLYMERASE; UNCLASSIFIED DRUG; URIDINE 5' TRIPHOSPHATE DERIVATIVE; URIDINE DERIVATIVE;

ARTICLE; BACTERIOPHAGE T7; ENZYME ACTIVITY; ENZYME SUBSTRATE; IN VITRO STUDY; PRIORITY JOURNAL; RNA SYNTHESIS; STRUCTURE ACTIVITY RELATION;

DNA-DIRECTED RNA POLYMERASES; KINETICS; MOLECULAR CONFORMATION; RNA; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; TRANSCRIPTION, GENETIC; URIDINE; URIDINE TRIPHOSPHATE; VIRAL PROTEINS;

EID: 0031018981     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(96)01400-7     Document Type: Article

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