Novel verrucosins from the skin of the Mediterranean nudibranch Doris verrucosa

Tetrahedron

Volumn 53, Issue 4, 1997, Pages 1491-1504

  Gavagnin, Margherita ^a   Ungur, Nicon ^a   Castelluccio, Francesco ^a   Cimino, Guido ^a  

^a CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DITERPENOID; PROTEIN KINASE C; UNCLASSIFIED DRUG; VERRUCOSIN DERIVATIVE;

ANIMAL TISSUE; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; ENZYME ACTIVATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; MOLLUSC; MORPHOGENESIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; SKIN; STEREOCHEMISTRY;

EID: 0031018694     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(96)01083-6     Document Type: Article

References (22)

1. On leave from Institute of Chemistry, Moldova Academy of Sciences, MD-2028 Chisinau, Republic of Moldova.
2. Associated to the National Institute for the Chemistry of Biological Systems (CNR).
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4. Cimino, G.; Gavagnin, M.; Sodano, G.; Puliti, R.; Mattia, C.A.; Mazzarella, L. Tetrahedron 1988, 44, 2301-2310.
5. Gavagnin, M.; Spinella, A.; Cimino, G.; Sodano, G. Tetrahedron Lett. 1990, 31, 6093-6094.
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8. Zubía, E.; Gavagnin, M.; Crispino, A.; Martinez, E.; Ortea, J.; Cimino, G. Experientia 1993, 49, 268-271.
9. Numbering of verrucosin-4 (7) is proposed as indicated in order to simplify the comparison with the other verrucosins.
10. Gonzalez, A. G.; Martin, J. D.; Rodriguez, M. L. An. Quim. 1976, 72, 1004-1014. Chem. Abstr. 1978, 88, 23188.
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17. A sample of methyl copalate was obtained from commercial "Copaiva Balsam" purchased from Lukas, W. Germany. Isolation procedure is described in Experimental.
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21. De Petrocellis, L.; Orlando, P.; Gavagnin, M.; Ventriglia, M. C.; Cimino, G.; Di Marzo, V. Experientia 1996, 874-877.
22. Numbering is proposed according to verrucosin-4 (7).