Effect of cholecystokinin octapeptide and atropine on human colonic motility, tone, and transit

Digestive Diseases and Sciences

Volumn 42, Issue 1, 1997, Pages 26-33

  O'Brien, Michael D ^a   Camilleri, Michael ^a   Thomforde, George M ^a   Wiste, Julie A ^a   Hanson, Russell B ^a   Zinsmeister, Alan R ^a  

^a MAYO CLINIC   (United States)

Author keywords

atropine; cholecystokinin; gastrocolonic tone; motility; transit

Indexed keywords

ATROPINE; CHOLECYSTOKININ OCTAPEPTIDE;

ADULT; ARTICLE; CLINICAL TRIAL; COLON MOTILITY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; GALLBLADDER CONTRACTION; GASTROINTESTINAL TRANSIT; HUMAN; HUMAN EXPERIMENT; INTESTINE TRANSIT TIME; INTRAVENOUS DRUG ADMINISTRATION; MALE; MANOMETRY; MOTOR PERFORMANCE; NORMAL HUMAN; PANCREAS SECRETION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCINTIGRAPHY;

ADULT; ATROPINE; COLON; DOUBLE-BLIND METHOD; FEMALE; GASTROINTESTINAL MOTILITY; GASTROINTESTINAL TRANSIT; HUMANS; MALE; MANOMETRY; PRESSURE; SINCALIDE;

EID: 0031018676     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018868601475     Document Type: Article

References (30)

1. Ford MJ, Camilleri M, Wiste JA, Hanson RB: Differences in colonic tone and phasic responses to a meal in the transverse and descending human colon. Gut 37:264-269, 1995
2. Fargeas MJ, Bassotti G, Fioramonti J, Bueno L: Involvement of different mechanisms in the stimulatory effects of cholecystokinin octapeptide on gastrointestinal and colonic motility in dogs. Can J Physiol Pharmacol 67:1205-1212, 1989
3. Hellstrom PM: Atropine and naloxone block the colonic contraction elicited by cholecystokinin and pentagastrin. Acta Physiol Scand 124:25-33, 1985
4. Liberge M, Arruebo MP, Bueno L: Role of hypothalamic cholecystokinin octapeptide in the colonic motor response to a meal in rats. Gastroenterology 100:441-449, 1991
5. Harvey RF, Read AE: Effect of cholecystokinin on colonic motility and symptoms in patients with the irritable-bowel syndrome. Lancet 1:1-3, 1973
6. Waller SL, Carvalhinhos A, Misiewicz JJ, Russell RI: Effect of cholecystokinin on colonic motility. Lancet 1:264, 1973
7. Lyrenas E, Abrahamsson H, Dotevall G: Failure of beta-adrenergic stimulation to affect cholecystokinin-stimulated sigmoid motility in man. Scand J Gastroenterol 20:1169-1174, 1985
8. Niederau C, Faber S, Karaus M: Cholecystokinin's role in regulation of colonic motility in health and in irritable bowel syndrome. Gastroenterology 102:1889-1898, 1992
9. Renny A, Snape WJ Jr, Sun EA, London R, Cohen S: Role of cholecystokinin in the gastrocolonic response to a fat meal. Gastroenterology 85:17-21, 1983
10. Kellow JE, Miller LJ, Phillips SF, Haddad AC, Zinsmeister AR, Charboneau JW: Sensitivities of human jejunum, ileum, proximal colon and gallbladder to cholecystokinin octapeptide. Am J Physiol 252:G345-G356, 1987
11. Mangel AW, Brazer SR, Smith JW, Filz JG, Taylor IL: Inhibition of colonic motility by cholecystokinin. Ann Med 24:341-342, 1992
12. Ford MJ, Camilleri M, Hanson RB, Wiste JA, Joyner MJ: Hyperventilation, central autonomic control, and colonic tone in humans. Gut 37:499-504, 1995
13. Steadman CJ, Phillips SF, Camilleri M, Talley NJ, Haddad A, Hanson R: Control of muscle tone in the human colon. Gut 33:541-546, 1992
14. von der Ohe MR, Camilleri M, Kvols LK, Thomforde GM: Motor dysfunction of the small bowel and colon in patients with the carcinoid syndrome and diarrhea. N Engl J Med 329:1073-1078, 1993
15. Camilleri M, Zinsmeister AR: Towards a relatively inexpensive, noninvasive, accurate test for colonic motility disorders. Gastroenterology 103:36-42, 1992
16. Proano M, Camilleri M, Phillips SF, Brown ML, Thomforde GM: Transit of solids through the human colon: Regional quantification in the unprepared bowel. Am J Physiol 258:G856-G862, 1990
17. von der Ohe MR, Camilleri M, Thomforde GM, Klee GG: Differential regional effects of octreotide on human gastrointestinal motor function. Gut 36:743-748, 1995
18. Levinson S, Bhasker M, Gibson TR, Morin R, Snape WJ Jr: Comparison of intraluminal and intravenous mediators of colonic response to eating. Dig Dis Sci 30:33-39, 1985
19. Jones RD, Chan K, Roulson CJ, Brown AG, Smith ID, Mya GH: Pharmacokinetics of flumazenil and midazolam. Br J Anaesth 70:286-292, 1993
20. Thiruvengadam R, DiMagno EP: Inactivation of human lipase by proteases. Am J Physiol 255:G476-G481, 1988
21. Hopman WPM, Kerstens PJSM, Jansen JBMJ, Risenbuseh G, Lamers CBHW: Effect of graded physiologic doses of cholecystokinin on gallbladder contraction measured by ultrasonography. Gastroenterology 89:1242-1247, 1985
22. Maton PN, Selden AC, Fitzpatrick ML, Chadwick VS: Infusion of CCK-octapeptide in man: Relation between plasma cholecystokinin concentrations and gallbladder emptying rates. Eur J Clin Invest 14:37-41, 1984
23. Walsh JH, Lamers CB, Valenzuela JE: Cholecystokinin-octapeptide immunoreactivity in human plasma. Gastroenterology 82:438-444, 1982
24. von der Ohe M, Hanson RB, Camilleri M: Comparison of simultaneous recordings of human colonic contractions by manometry and a barostat. Neurogastroenterol Motil 6:213-222, 1994
25. Bueno L: Involvement of brain CCK in the adaptation of gut motility to digestive status and stress: A review. J Physiol (Paris) 87:301-306, 1993
26. Gue M, Gleizes-Escala C, Del Rio-Lacheze C, Junien JL, Bueno L: Reversal of CRF- and dopamine-induced stimulation of colonic motility by CCK and igmesine (JO 1784) in the rat. Br J Pharmacol 111:930-934, 1994
27. Barone FC, Bondinell WE, Labosh TJ, White RF, Ormsbee HS: Cholecystokinin stimulates neuronal receptors to produce contraction of the canine colon. Life Sci 44:533-542, 1989
28. Wiley J, Owyang C: Participation of serotonin and substance P in the action of cholecystokinin on colonic motility. Am J Physiol 252:G431-G435, 1987
29. von der Ohe MR, Camilleri M, Carryer PW: A patient with localized megacolon and intractable constipation: Evidence for impairment of colonic muscle tone. Am J Gastroenterol 89:1867-1870, 1994
30. Wiley J, Tatum D, Keinath R, Owyang C: Participation of gastric mechanoreceptors and intestinal chemoreceptors in the gastrocolonic response. Gastroenterology 94:1144-1149, 1988