Tissue-specific expression of interleukin-4 induces extracellular matrix accumulation and extravasation of B cells

Laboratory Investigation

Volumn 76, Issue 1, 1997, Pages 117-128

  Mueller, Regula ^a   Krahl, Troy ^a   Sarvetnick, Nora ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE; INTERLEUKIN 4;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; EXTRACELLULAR MATRIX; EXTRAVASATION; IMMUNE RESPONSE; IMMUNOPATHOLOGY; IMMUNOREGULATION; INTRACELLULAR TRANSPORT; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE SPECIFICITY;

ANIMALS; B-LYMPHOCYTES; CELL ADHESION MOLECULES; EXTRACELLULAR MATRIX; FEMALE; HUMANS; IMMUNOGLOBULINS; INFLAMMATION; INSULIN; INTERLEUKIN-4; MICE; MICE, TRANSGENIC; MUCOPROTEINS; ORGAN SPECIFICITY; PANCREAS; PROMOTER REGIONS (GENETICS); RECEPTORS, LYMPHOCYTE HOMING; RECOMBINANT FUSION PROTEINS; T-LYMPHOCYTES;

EID: 0031017990     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (59)

1. Allison J, Malcolm L, Chosich N, and Miller JFAP (1992). Inflammation but not autoimmunity occurs in transgenic mice expressing constitutive levels of interleukin-2 in islet β cells. Eur J Immunol 22:1115-1121.
2. Bignold LP (1995). The eosinophil leukocyte: Controversies of recruitment and function. Experientia 51:317-327.
3. Bochner BS, Luscinskas FW, Gimbrone MA, Newman W, Sterbinsky SA, Derse-Anthony CP, Klunk D, and Schleimer RP (1991). Adherence of human basophils, eosinophils, and neutrophils to interleukin-1-activated human vascular endothelial cells: Contribution of endothelial cell adhesion molecules. J Exp Med 173:1553-1556.
4. Boros DL (1994). The role of cytokines in the formation of the schistosome egg granuloma. Immunobiology 191:441-450.
5. Bousquet J, Chanez P, Lacoste J, Barneon G, Ghavanian N, Enander I, Venge P, Ahlstedt S, Simony-Lafontaine J, and Godard P (1990). Eosinophilic inflammation in asthma. N Engl J Med 323:1033-1039.
6. Briscoe DM, Cotran RS, and Pober JS (1992). Effects of tumor necrosis factor, lipopolysaccharide, and IL-4 on the expression of vascular cell adhesion molecule-1 in vivo. J Immunol 149:2954-2960.
7. Bruijnzeel-Koomen CAFM, Van Wichen DF, Spry CJF, Venge P, and Bruijnzeel PLB (1988). Active participation of eosinophils in patch test reactions to inhalant allergens in patients with atopic dermatitis. Br J Dermatol 118:229-238.
8. Campbell IL, Hobbs MV, Dockter J, Oldstone MBA, and Allison J (1994). Islet inflammation and hyperplasia induced by the pancreatic islet-specific overexpression of interleukin-6 in transgenic mice. Am J Pathol 145:157-166.
9. Clinchy B, Elenstroem C, Severinson E, and Moeller G (1991). T and B cell collaboration: Induction of motility in small, resting B cells by interleukin-4. Eur J Immunol 21:1445-1451.
10. Clinchy B and Moeller G (1994). Interleukin-4 induces in vitro migration in naive B cells through direct mechanisms. Scand J Immunol 40:429-436.
11. Corrigan CJ and Kay AB (1992). T cells and eosinophils in the pathogenesis of asthma. Immunol Today 13:501-507.
12. DiCosmo BF, Picarella D, and Flavell RA (1994). Local production of human IL-6 promotes insulitis but retards the onset of insulin-dependent diabetes mellitus in non-obese diabetic mice. Int Immunol 6:1829-1837.
13. Dobrina A, Menegazzi R, Carlos TM, Nardon E, Cramor R, Zacchi T, Harlan JM, and Patriarca P (1991). Mechanisms of eosinophil adherence to cultured vascular endothelial cells. J Clin Invest 88:20-26.
14. Elenstroem-Magnusson C, Chen W, Clinchy G, Oebrink B, and Severinson E (1995). IL-4-induced B cell migration involves transient interactions between β1 integrins and extracellular matrix components. Int Immunol 7:567-573.
15. Elliott EA and Flavell RA (1994). Transgenic mice expressing constitutive levels of IL-2 in islet β cells develop diabetes. Int Immunol 6:1629-1637.
16. Finkelman FD, Holmes J, Katona IM, Urban JF, Beckmann MP, Park LS, Schooley KA, Coffman RL, Mosmann TR, and Paul WE (1990). Lymphokine control of in vivo immunoglobulin isotype selection. Annu Rev Immunol 8:303-333.
17. Gleich GJ and Adolphson CR (1986). The eosinophilic leukocyte: Structure and function. Adv Immunol 39:177-253.
18. Golumbek PT, Lazenby AJ, Levitsky HI, Jaffee LM, Karasuyama H, Baker M, and Pardoll DM (1991). Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4. Science 254:713-716.
19. Hallmann R, Mayer DN, Berg EL, Broermann R, and Butcher EC (1995). Novel mouse endothelial surface marker is suppressed during differentiation of the blood brain barrier. Dev Dyn 202:325-332.
20. Hiester AA, Metcalf DR, and Campbell PA (1992). Interleukin-4 is chemotactic for mouse macrophages. Cell Immunol 139:72-80.
21. Higuchi Y, Herrera P, Muniesa P, Huarte J, Belin D, Ohashi P, Aichele P, Orci L, Vassalli J-D, and Vassalli P (1992). Expression of a tumor necrosis factor a transgene in murine pancreatic β cells results in severe and permanent insulitis without evolution towards diabetes. J Exp Med 76:1719-1731.
22. Hogg N, Bates PA, and Harvey J (1991). Structure and function of intercellular adhesion molecule-1. In: Hogg N, editor. Integrins and ICAM-1 in immune responses. Basel: Karger, 98-115.
23. Howard M, Farrar J, Hilfiker M, Johnson B, Takatsu K, Hamaoka T, and Paul WE (1982). Identification of a T cell-derived B cell growth factor distinct from interleukin-2. J Exp Med 155:914-923.
24. Lee M-S, Gu D, Feng L, Curriden S, Arnush M, Krahl T, Gurushanthaiah D, Wilson CB, Loskutoff DL, Fox H, and Sarvetnick N (1995). Accumulation of extracellular matrix and developmental dysregulation in the pancreas by transgenic production of TGF-β1. Am J Pathol 147:42-52.
25. Lee M-S, Wogensen L, Shizuru J, Oldstone MBA, and Sarvetnick N (1994). Pancreatic islet production of murine interleukin-10 does not inhibit immune-mediated tissue destruction. J Clin Invest 93:1332-1338.
26. Masinovsky B, Urdal D, and Gallatin WM (1990). IL-4 acts synergistically with IL-1β to promote lymphocyte adhesion to microvascular endothelium by induction of vascular cell adhesion molecule-1. J Immunol 145:2886-2895.
27. Mathew RC and Buros DL (1986). Anti-L3T4 antibody treatment suppresses hepatic granuloma formation and abrogates antigen-induced interleukin-2 production in Schistosoma mansoni infection. Infect Immun 54:820-826.
28. Monroe JG, Haldar S, Prystowsky MB, and Lammie P (1988). Lymphokine regulation of inflammatory processes: lnterleukin-4 stimulates fibroblast proliferation. Clin Immunol Immunopathol 49:292-298.
29. Mosmann TR, Bond MW, Coffman RL, Ohara J, and Paul WE (1986). T-cell and mast cell lines respond to B cell stimulatory factor-1. Proc Natl Acad Sci USA 83:5654-5658.
30. Mueller R, Krahl T, and Sarvetnick N (1996). Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic mice. J Exp Med 184:1093-1099.
31. Noelle R, Krammer PH, Ohara J, Uhr JW, and Vitetta ES (1984). Increased expression of Ia antigens on resting B cells: An additional role for B-cell growth factor. Proc Natl Acad Sci USA 81:6149-6153.
32. Paul WE (1991). Interleukin-4: A prototypic immunoregulatory lymphokine. Blood 77:1859-1870.
33. Picarella D, Kratz A, Li C-B, Ruddle NH, and Flavell RA (1992). Insulitis in transgenic mice expressing TNF-β (lymphotoxin) in the pancreas. Proc Natl Acad Sci USA 89: 10036-10040.
34. Picarella DE, Kratz A, Li C-B, Ruddle NH, and Flavell RA (1993). Transgenic tumor necrosis factor (TNF)-α production in pancreatic islets leads to insulitis, not diabetes. Distinct patterns of inflammation in TNF-α and TNF-β transgenic mice. J Immunol 150:4136-4150.
35. Picker L (1992). Mechanisms of lymphocyte homing. Curr Opin Immunol 4:277-286.
36. Postlethwaite AE and Seyer JM (1991). Fibroblast chemotaxis induction by human recombinant interleukin-4. J Clin Invest 87:2147-2152.
37. Roehm NW, Leibson HJ, Zlotnik A, Kappler J, Marrack P, and Gambier JC (1984). Interleukin-induced increase in Ia expression by normal mouse B cells. J Exp Med 160:679-694.
38. Rothenberg ME, Luster AD, and Leder P (1995). Murine eotaxin: An eosinophil chemoattractant inducible in endothelial cells and in interleukin 4-induced tumor suppression. Proc Natl Acad Sci USA 92:8960-8964.
39. Sarvetnick N, Liggitt D, Pitts SL, Hansen SE, and Stewart TA (1988). Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma. Cell 52:773-782.
40. Schleimer RP, Sterbinsky SA, Kaiser J, Bickel CA, Klunk DA, Tomioka K, Newman W, Luscinskas FW, Gimbrone MA, McIntyre BW, and Bochner BS (1992). IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium: Association with expression of VCAM-1. J Immunol 148:1086-1092.
41. Schneppenheim R, Thomas KB, and Sutor AH (1995). von Willebrand disease in childhood. Semin Thromb Hemost 21:261-275.
42. Snapper CM and Paul WE (1987). Interferon-γ and B cell stimulatory factor-1 reciprocally regulate Ig isotype production. Science 236:944-947.
43. Springer TA (1994). Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm. Cell 76:301-314.
44. Stewart TA, Hultgren B, Huang X, Pitts-Meek S, Hully J, and MacLachlan NJ (1993). Induction of type 1 diabetes by interferon-α in transgenic mice. Science 260:1942-1946.
45. Streeter PR, Berg EL, Rouse BTN, Bargatze RF, and Butcher EC (1988). A tissue-specific endothelial cell molecule involved in lymphocyte homing. Nature 331:41-46.
46. Takatsu K, Tominaga A, Harada N, Mita S, Matsumoto M, Takahashi T, Kikuchi Y, and Yamaguchi N (1988). T cell-replacing factor (TRF)/interleukin 5 (IL-5): Molecular and functional properties. Immunol Rev 102:107-135.
47. Tepper RI (1994). The eosinophil-mediated antitumor acitvity of interleukin-4. J Allergy Clin Immunol 94:1225-1231.
48. Tepper RI, Coffman RL, and Leder P (1992). An eosinophil-dependent mechanism for the antitumor effect of interleukin-4. Science 257:548-551.
49. Tepper RI, Pattengale PK, and Leder P (1989). Murine interleukin-4 displays potent anti-tumor activity in vivo. Cell 57:503-512.
50. Thornhill MH and Haskard DO (1990). IL-4 regulates endothelial cell activation by IL-1, TNF-α, or IFN-γ. J Immunol 145:865-872.
51. Tsuji K, Nakahata T, Takagi M, Kobayashi T, Ishiguro A, Kikuchi T, Naganuma K, Koike K, Miyajima A, Arai K, and Akabane T (1990). Effects of interleukin-3 and interleukin-4 on the development of "connective tissue-type" mast cells: Interleukin-3 supports their survival and interleukin-4 triggers and supports their proliferation synergistically with interleukin-3. Blood 75:421-427.
52. Wagner DD and Bonfanti R (1991). Von Willebrand factor and the endothelium. Mayo Clin Proc 66:621-628.
53. Wahl SM, Hunt DA, Allen JB, Wilder RL, Paglia L, and Hand AR (1986). Bacterial cell wall-induced hepatic granulomas: An in vivo model of T cell-dependent fibrosis. J Exp Med 163:884-902.
54. Wahl SM, Malone DG, and Wilder RL (1985). Spontaneous production of fibroblast activating factor(s) by synovial inflammatory cells: A potential mechanism for enhanced tissue destruction. J Exp Med 161:210-222.
55. Walsh GM, Mermod JJ, Hartnell A, and Kay AB (1991). Human eosinophil, but not neutrophil, adherence to IL-1-stimulated human umbilical vascular endothelial cells is α4β1 (very late antigen-4) dependent. J Immunol 146:4319-4323.
56. Widmer MB and Grabstein KH (1987). Regulation of cytolytic T-lymphocyte generation by B-cell stimulatory factor. Nature 326:795-798.
57. Wilkinson PC and Islam LN (1989). Recombinant IL-4 and IFN-γ activates locomotor capacity in human B lymphocytes. Immunology 67:237-243.
58. Wogensen L, Huang X, and Sarvetnick N (1993). Leukocyte extravasation into the pancreatic tissue in transgenic mice expressing interleukin-10 in the islets of Langerhans. J Exp Med 178:175-185.
59. Yu JS, Wei MX, Chiocca A, Martuza RL, and Tepper RI (1993). Treatment of glioma by engineered interleukin 4-secreting cells. Cancer Res 53:3125-3128.