Neurotrophins: The yin and yang of nerve growth factor

Current Biology

Volumn 7, Issue 1, 1997, Pages

  Davies, Alun M ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0031017281     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0960-9822(06)00016-9     Document Type: Review

References (23)

1. Davies AM: Role of neurotrophins in the developing nervous system. J Neurobiol 1994, 25:1334-1348.
2. Lewin GR, Barde YA: The physiology of neurotrophins. Annu Rev Neurosci 1996, 19:289-317.
3. Miyata Y, Kashihara Y, Homma S, Kuno M: Effects of nerve growth factor on the survival and synaptic function of la sensory neurons axotomized in neonatal rats. J Neurosci 1986, 6:2012-2018.
4. Sendtner M, Holtmann B, Kolbeck R, Thoenen H, Barde Y-A: Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature 1992, 360:757-759.
5. von Bartheld C, Kinoshita Y, Prevette D, Yin QW, Oppenheim RW, Bothwell M: Positive and negative effects of neurotrophins on the isthmo-optic nucleus in chick embryos. Neuron 1994, 12:639-654.
6. Frade JM, Rodriguez-Tebar A, Barde YA: Induction of cell death by endogenous nerve growth factor through its p75 receptor. Nature 1996, 383:166-168.
7. Casaccia-Bonnefil P, Carter BD, Dobrowsky RT, Chao MV: Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75. Nature 1996, 383:716-719.
8. Bothwell M: Functional interactions of neurotrophins and neurotrophin receptors. Annu Rev Neurosci 1995, 18:223-253.
9. Davies AM, Lee KF, Jaenisch R: p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins. Neuron 1993, 11:565-574.
10. Lee KF, Davies AM, Jaenisch R: p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF. Development 1994, 120:1027-1033.
11. Lee KF, Li E, Huber LJ, Landis SC, Sharpe AH, Chao MV, Jaenisch R: Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell 1992, 69:737-749.
12. Lee KF, Bachman K, Landis S, Jaenisch R: Dependence on p75 for innervation of some sympathetic targets. Science 1994, 263:1447-1449.
13. Clary DO, Reichardt LF: An alternatively spliced form of the nerve growth factor receptor TrkA confers an enhanced response to neurotrophin-3. Proc Natl Acad Sci USA 1994, 91:11133-11137.
14. Benedetti M, Levi A, Chao MV: Differential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsiveness. Proc Natl Acad Sci USA 1993, 90:7859-7863.
15. LNGFR in NT-4 signalling. EMBO J 1995, 14:1979-1990.
16. Rabizadeh S, Oh J, Zhong LT, Yang J, Bitler CM, Butcher LL, Bredesen DE: Induction of apoptosis by the low-affinity NGF receptor. Science 1993, 261:345-348.
17. Barrett GL, Bartlett PF: The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development. Proc Natl Acad Sci USA 1994, 91:6501-6505.
18. Anton ES, Weskamp G, Reichardt LF, Matthew WD: Nerve growth factor and its low-affinity receptor promote Schwann cell migration. Proc Natl Acad Sci USA 1994, 91:2795-2799.
19. Ernfors P, Henschen A, Olson L, Persson H: Expression of nerve growth factor receptor mRNA is developmentally regulated and increased after axotomy in rat spinal cord motoneurons. Neuron 1989, 2:1605-1613.
20. Curtis R, Adryan, KM, Stark JL, Park JS, Compton DL, Weskamp G, Huber LJ, Chao MV, Jaenisch R, Lee K, et al.: Differential role of the low affinity neurotrophin receptor (p75) in retrograde axonal transport of the neurotrophins. Neuron 1995, 14:1201-1211.
21. Nagata S: Telling cells their time is up. Curr Biol 1996, 6:1241-1243.
22. Hannun YA, Obeid LM: Ceramide: an intracellular signal for apoptosis. Trends Biochem Sci 1995, 20:73-77.
23. Ito A, Horigome K: Ceremide prevents neuronal programmed cell death induced by nerve growth factor deprivation. J Neurochem 1995, 65:463-466.