Proliferation and production of interferon-gamma (IFN-γ) and IL-4 in response to Staphylococcus aureus and Staphylococcal superantigen in childhood atopic dermatitis

Clinical and Experimental Immunology

Volumn 107, Issue 2, 1997, Pages 392-397

  Campbell, D E ^a   Kemp, A S ^a  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

Author keywords

atopic dermatitis; child; IL 4; interferon gamma; Staphylococcus

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 4; STAPHYLOCOCCUS ENTEROTOXIN B; SUPERANTIGEN;

ARTICLE; ATOPIC DERMATITIS; CELLULAR IMMUNITY; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0031016997     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.1997.278-ce1172.x     Document Type: Article

References (31)

1. Rajka G. Clinical aspects. In: Rajka G, ed. Essential aspects of atopic dermatitis. Berlin: Springer Verlag, 1989: 7.
2. Leung DY, Bhan AK, Schneeberger EE, Geha RS. Characterization of the mononuclear cell infiltrate in atopic dermatitis using monoclonal antibodies. J Allergy Clin Immunol 1983; 72:47-50.
3. Jujo K, Renz H, Abe J, Gelfand EW, Leung DY. Decreased interferon gamma and increased interleukin-4 production in atopic dermatitis promotes IgE synthesis. J Allergy Clin Immunol 1992; 90:323-6.
4. Reinhold U, Kukel, S, Goeden B, Neumann U, Kreysel HW. Functional characterization of skin-infiltrating lymphocytes in atopic dermatitis. Clin Exp Immunol 1991; 86:444-8.
5. Tang ML, Varigos G, Kemp AS. Reduced interferon-gamma IFN-gamma) secretion with increased IFN-gamma mRNA expression in atopic dermatitis: evidence for a post-transcriptional defect. Clinical Exp Immunol 1994; 97:483-90.
6. Hoeger PH, Lenz W, Boutonnier A, Fournier JM. Slaphylococcal skin colonization in children with atopic dermatitis: prevalence, persistence, and transmission of toxigenic and nontoxigenic strains. J Infect Dis 1992; 165:1064-8.
7. Noble WC. Skin carriage of the Micrococcaceae. J Clin Pathol 1969; 22:249-53.
8. Luber H, Amornsiripanitch S, Lucky AW. Mupirocin and the eradication of Staphylococcus aureus in atopic dermatitis. Arch Dermatol 1988; 124:853-4.
9. Stalder JF, Fleury M, Sourisse M, Rostin M, Pheline F, Litoux P. Local steroid therapy and bacterial skin flora in atopic dermatitis. Brit J Dermatol 1994; 131:536-40.
10. Lever R, Hadley K, Downey D, Mackie R. Staphylococcal colonization in atopic dermatitis and the effect of topical mupirocin therapy. Brit J Dermatol 1988; 119:189-98.
11. Leung DY, Harbeck R, Bina P et al. Presence of IgE antibodies to Staphylococcal exotoxins on the skin of patients with atopic dermatitis. Evidence for a new group of allergens. J Clin Invest 1993; 92:1374-80.
12. Strange P, Skov L, Lisby S, Nielsen PL, Baadsgaard O. Staphylococcal enterotoxin B applied on intact normal and intact atopic skin induces dermatitis. Arch Dermatol 1996; 132:27-33.
13. Hofer MF, Lester MR, Schlievert PM, Leung DY. Upregulation of IgE synthesis by Staphylococcal toxic shock syndrome toxin 1 in peripheral blood mononuclear cells from patients witha topic dermatitis. Clin Exp Allergy 1995; 25:1218-27.
14. Konig B, Neuber K, Konig W. Responsiveness of peripheral blood mononculear cells from normal and atopic donors to microbial superantigens. Int Arch of Allergy Immunol 1995; 106:124-33.
15. Lester MR, Hofer MF, Gately M, Trumble A, Leung DY. Down-regulating effects of IL-4 and IL-10 on the IFN-gamma response in atopic dermatitis. J Immunol 1995; 154:6174-81.
16. Simons MJ, Fitzgerald MG. Apparent dissociation of antigen responsiveness and antibody production by human small lymphocytes in culture. Clin Exp Immunol 1969; 4:55-63.
17. Zlabinger GJ, Mannhalter JW, Ahmad R, Eibl MM. Reduced antigen-induced proliferation and surface Ia expression of peripheral blood T cells following tetanus booster immuniztion. Clin Immunol Immunopathol 1985; 34:254-62.
18. Higaki Y, Hauser C, Rilliet A, Saurat JH. Increased in vitro cell-meidated immune response to Staphylococcal antigens in atopic dermatitis. J Am Acad Dermatol 1986; 15:1204-9.
19. Neuber K, Steinrucke K, Ring J. Staphylococcal enterotoxin B affects in vitro IgE synthesis, interferon-gamma, interleukin-4 and interleukin-5 production in atopic eczema. Int Arch Allergy 1995; 107:179-82.
20. + peripheral blood T lymphocytes from patients with atopic eczema (abstract) J Allergy Clin Immunol 1994; 93:221.
21. + subpopulations. Scand J Immunol 1996; 43:391-7.
22. + T lymphocytes in atopic patients. J Immunol 1990; 144:4651-6.
23. Parronchi P, Macchia D, Piccinni MP et al. Allergen- and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production. Proc Natl Acad Sci USA 1991; 88:4538-42.
24. Huang S, Hundricks W, Althage A et al. Immune response in mice that lack the interferon-gamma receptor. Science 1993; 259:1742-5.
25. Jahreis A, Yousif Y, Rump JA et al. Two novel cationic Staphylococcal proteins induce IL-2 secretion, proliferation and immunoglobulin synthesis in peripheral blood mononuclear cells (PBMC) of both health controls and patients with common variable immunodeficiency (CVID). Clin Exp Immunol 1995; 100:406-11.
26. Fern J, Good MF. Promiscuous malaria peptide epitope stimulates CD45RA T cells for peripheral blood of nonexposed donors. J Immunol 1992; 148:907-13.
27. Mosmann TP, Sad S. The expanding universe of T cell subsets: Th1, Th2 and more. Immunol Today 1996; 17:138-46.
28. + T-cell subsets in experimental cutaneous leishmaniasis. [Review]. Res Immunol 1991; 142:32-36.
29. Carvalho EM, Bacellar O, Brownell C, Regis T, Coffman RL, Reed SG. Restoration of IFN-gamma production and lymphocyte proliferation in visceral leishmaniasis. J Immunol 1994; 152:5949-56.
30. Xiong H, Kawamura I, Nishibori T, Mitsuyama M. Cytokine gene expression in mice at an early stage of infection with various strains of Listeria spp. differing in virulence. Infect Immun 1994; 62:3649-54.
31. Roessner K, Fikrig E, Russell JQ, Cooper SM, Flavell RA, Budd RC. Prominent T lymphocyte response to Borrelia burgdorferi from peripheral blood of unexposed donors. Eur J Immunol 1994; 24:320-4.