Patterns of graft infiltration and cytokine gene expression during the first 10 days of kidney transplantation

Transplantation

Volumn 63, Issue 3, 1997, Pages 374-380

  McLean, Adam G ^a,b   Hughes, David ^a   Welsh, Ken I ^a   Gray, Derek W R ^a   Roake, Justin ^a   Fuggle, Susan V ^a   Morris, Peter J ^a   Dallman, Margaret J ^a,c  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b ROYAL FREE HOSPITAL   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN; CYTOKINE; GAMMA INTERFERON; HLA DR ANTIGEN; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; METHYLPREDNISOLONE; STEROID;

ARTICLE; ASPIRATION BIOPSY; CELL INFILTRATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOLOGY; DRUG BLOOD LEVEL; GENE EXPRESSION; HLA SYSTEM; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; MONONUCLEAR CELL; PRIORITY JOURNAL; RADIOIMMUNOASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ACUTE DISEASE; CELL MOVEMENT; CYTOKINES; GENE EXPRESSION REGULATION; GRAFT REJECTION; HISTOCOMPATIBILITY TESTING; HUMANS; KIDNEY TRANSPLANTATION; POSTOPERATIVE PERIOD;

EID: 0031016852     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199702150-00008     Document Type: Article

References (28)

1. Solez K, Axelson RA, Benediktsson H, et al. International standardization criteria for the histologie diagnosis of renal allograft rejection: the Banff working classification of kidney transplant pathology. Kidney Int 1993; 44: 441.
2. Rush DN, Henry SF, Jeffery JR, Schroeder TJ, Gough J. Histological findings in early routine biopsies of stable renal allograft recipients. Transplantation 1994; 57: 208.
3. Hughes D. Fine needle aspiration cytology in the monitoring of human renal allograft progress. Immunol Lett 1991; 29: 147.
4. Gray DW, Richardson A, Hughes D, et al. A prospective, randomized, blind comparison of three biopsy techniques in the management of patients after renal transplantation. Transplantation 1992; 53: 1226.
5. Dallman MJ, Larsen CP, Morris PJ. Cytokine gene transcription in vascularized organ grafts: analysis using the polymerase chain reaction. J Exp Med 1991; 174: 493.
6. Dantal J, Soulillou JP. Use of monoclonal antibodies in human transplantation. Curr Opin Immunol 1991; 3: 740.
7. Steiger J, Nickerson PW, Steurer W, Moscovitch-Lopatin M, Strom TB. IL-2 knockout recipient mice reject islet cell allografts. J Immunol 1995; 155: 489.
8. Mossman TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986; 136: 2348.
9. Del-Prete G, Maggi E, Romagnani S. Human Th1 and Th2 cells: functional properties, mechanisms of regulation, and role in disease. Lab Invest 1994; 70: 299.
10. Dallman MJ, Roake J, Hughes D, Toogood G, Morris PJ. Sequential analysis of IL-2 gene transcription in renal transplants. Transplantation 1992; 53: 683.
11. Pattison J, Nelson PJ, Huie P, et al. RANTES chemokine expression in cell-mediated transplant rejection of the kidney. Lancet 1994; 343: 209.
12. Lipman ML, Stevens AC, Bleakley RC, et al. The strong correlation of cytotoxic T lymphocyte-specific serine protease gene transcripts with renal allograft rejection. Transplantation 1992; 53: 73.
13. Dallman MJ, Montgomery RA, Larsen CP, Wanders A, Wells AF. Cytokine gene expression: analysis using Northern blotting, polymerase chain reaction and in situ hybridisation. Immunol Rev 1991; 119: 163.
14. McWhinnie DL, Thompson JF, Taylor HM, et al. Morphometric analysis of cellular infiltration assessed by monoclonal antibody labeling in sequential human renal allograft biopsies. Transplantation 1986; 42: 352.
15. Dallman MJ, Shiho O, Page TH, Wood KJ, Morris PJ. Peripheral tolerance to alloantigen results from altered regulation of the interleukin 2 pathway. J Exp Med 1991; 173: 79.
16. Noronha IL, Eberlein-Gonska M, Hartley B, Stephens S, Cameron JS, Waldherr R. In situ expression of tumor necrosis factor-alpha, interferon gamma, and interleukin-2 receptors in renal allograft biopsies. Transplantation 1992; 54: 1017.
17. Blancho G, Gianello P, Germana S, Baetscher M, Sachs DH, LeGuern C. Molecular identification of porcine interleukin 10: regulation of expression in a kidney allograft model. Proc Natl Acad Sci USA 1995; 92: 2800.
18. Raasveld MH, Weening JJ, Kerst JM, Surachno S, ten-Berge RJ. Local production of interleukin-6 during acute rejection in human renal allografts. Nephrol Dial Transplant 1993; 8: 75.
19. Krams SM, Falco DA, Villanueva JC, et al. Cytokine and T cell receptor gene expression at the site of allograft rejection. Transplantation 1992; 53: 151.
20. Vandenbroeke C, Caillat-Zucman S, Legendre C, et al. Differential in situ expression of cytokines in renal allograft rejection. Transplantation 1991; 51: 602.
21. Nast CC, Zuo XJ, Prehn J, Danovitch GM, Wilkinson A, Jordan SC. Gamma-interferon gene expression in human renal allograft fine-needle aspirates. Transplantation 1994; 57: 498.
22. Merville P, Pouteil-Noble C, Wijdenes J, Poyaux L, Touraine JL, Banchereau J. Detection of single cells secreting IFN-gamma, IL-6, and IL-10 in irreversibly rejected human kidney allografts and their modulation by IL-2 and IL-4. Transplantation 1993; 55: 639.
23. Bugeon L, Cuturi MC, Paineau J, Chabannes D, Soulillou JP. Decreased IFN-gamma and IL-2 mRNA expression in peripheral tolerance to heart allografts with conserved granzyme A, perforin, and MHC antigens mRNA expression. Transplant Proc 1993; 25: 314.
24. Wu CJ, Lovett M, Wong-Lee J, et al. Cytokine gene expression in rejecting cardiac allografts. Transplantation 1992; 54: 326.
25. Nickerson P, Steurer W, Steiger J, Zheng X, Steele AW, Strom TB. Cytokines and the Th1/Th2 paradigm in transplantation. Curr Opin Immunol 1994; 6: 757.
26. Kirk AD, Ibrahim MA, Bollinger RR, Dawson DV, Finn OJ. Renal allograft infiltrating lymphocytes: a prospective analysis of in vitro growth characteristics and clinical relevance. Transplantation 1992; 53: 329.
27. Cunningham DA, Dunn MJ, Yacoub MH, Rose ML. Local production of cytokines in the human cardiac allograft: a sequential study. Transplantation 1994; 57: 1333.
28. Schreiner GF, Kamei T, Lefkowith J, Flye MW. Modulation of the kinetics of the initial leukocyte migration into renal allografts by 16,16-dimethyl PGE2. Transplantation 1993; 56: 417.