Actin is a target antigen of anti-neutrophil cytoplasmic antibodies (ANCA) in autoimmune hepatitis type-1

Journal of Hepatology

Volumn 26, Issue 1, 1997, Pages 37-47

  Orth, Thomas ^a   Gerken, Guido ^a   Kellner, Roland ^a   Meyer Zum Büschenfelde, Karl Hermann ^a   Mayet, Werner Johannes ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

actin; anti neutrophil cytoplasmic antibodies (ANCA); autoimmune hepatitis; neutrophils

Indexed keywords

ACTIN;

ADULT; AGED; ARTICLE; AUTOIMMUNITY; CLINICAL ARTICLE; FEMALE; HEPATITIS; HUMAN; MALE; NEUTROPHIL; PRIORITY JOURNAL;

EID: 0031015227     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(97)80007-4     Document Type: Article

References (35)

1. Krawitt EL. Autoimmune hepatitis. N Engl J Med. 334:1996;897-903.
2. Czaja AJ. Chronic active hepatitis: The challenge for a new nomenclature. Ann Intern Med. 119:1993;510-517.
3. Johnson PJ, McFarlane IG. Meeting report. International Autoimmune Hepatitis Group. Hepatology. 18:1993;998-1005.
4. Manns M, Gerken G, Kyriatsoulis A, Staritz M, Meyer zum Büschenfelde K-H. Characterization of a new subgroup of autoimmune chronic active hepatitis by autoantibodies against a soluble liver antigen. Lancet. i:1987;292-294.
5. Hardarson S, LaBrecque DR, Mitros FA, Neil GA, Goeken JA. Antineutrophil cytoplasmic antibody in inflammatory bowel and hepatobiliary diseases. Am J Clin Pathol. 99:1993;277-281.
6. Mulder AHL, Horst G, Haagsma EB, Limburg PC, Kleibeuker JH, Kallenberg CGM. Prevalence and characterization of neutrophil cytoplasmic autoantibodies in autoimmune liver disease. Hepatology. 17:1993;411-417.
7. Warny M, Brenard R, Cornu C, Tomasi JP, Geubel AP. Antineutrophil antibodies in chronic hepatitis and the effect of interferon therapy. J Hepatol. 17:1993;294-300.
8. Targan SR, Landers C, Vidrich A, Czaja AJ. High-titer antineutrophil cytoplasmic antibodies in type-1 autoimmune hepatitis. Gastroenterology. 108:1995;1159-1166.
9. Van der Woude FJ, Rasmussen N, Lobatto S, Wiik A, Permin H, Van es LA, van der Giessen M, van der Hem GK, The TH. Autoantibodies to neutrophils and monocytes: a new tool for diagnosis and a marker of disease activity in Wegener's granulomatosis. Lancet. i:1985;425-429.
10. Nolle B, Specks U, Lüdemann J, Rohrbach MS, DeRemee RA, Gross WL. Anticytoplasmic autoantibodies: their immunodiagnostic value in Wegener's granulomatosis. Ann Intern Med. 111:1989;28-40.
11. Goldschmeding R, van der Schoot CE, ten Bokkel Huinink D, Hack CE, van den Ende ME, Kallenberg CGM, von dem Borne AEGK. Wegener's granulomatosis autoantibodies identify a novel diisopropylfluorophosphate-binding protein in the lysosomes of normal human neutrophils. J Clin Invest. 84:1989;1577-1587.
12. Niles JL, McCluskey RT, Ahmad MF, Arnaout MA. Wegener's granulomatosis autoantigen is a novel neutrophil serine proteinase. Blood. 74:1989;1888-1893.
13. Jenne DE, Tschopp J, Lüdemann J, Utecht B, Gross WL. Wegener's autoantigen decoded. Nature. 346:1990;520.
14. Falk RJ, Jenette JC. Anti-neutrophil cytoplasmic antibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis. N Engl J Med. 318:1988;1651-1657.
15. Gross WL, Schmitt WH, Csernok E. ANCA and associated diseases: immunodiagnostic and pathogenetic aspects. Clin Exp Immunol. 91:1993;1-12.
16. Duerr RH, Targan SR, Landers CJ, Sutherland LR, Shanahan F. Anti-neutrophil cytoplasmic antibodies in ulcerative colitis. Comparison with other colitides/diarrhoeal illness. Gastroenterology. 100:1991;1590-1596.
17. Orth T, Mayet WJ, Gerken G, Lohse AW, Meyer zum Büschenfelde KH. Antineutrophile zytoplasmatische Antikörper (ANCA) bei Autoimmunhepatitis (Abstract). Z Gastroenterol. 33:1995;70.
18. Mayet WJ, Hess G, Gerken G, Felde KH. Treatment of chronic type B hepatitis with recombinant α-interferon induces autoantibodies not specific for autoimmune chronic hepatitis. Hepatology. 1:1989;24-28.
19. Manns M, Meyer zum Büschenfelde KH, Slusarczyk J, Dienes HP. Detection of liver-kidney microsomal autoantibodies by radioimmunoassay and their relation to anti-mitochondrial antibodies in inflammatory liver diseases. Clin Exp Immunol. 57:1984;600-607.
20. Wiik A, Rasmussen N, Wieslander J. Methods to detect autoantibodies to neutrophilic granulocytes. Van Venrooij WJ, Maini RN. Manual of Biological Markers of Disease. 1993;A9-A12 Kluwer, Dordrecht.
21. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein using the princple of protein dye binding. Anal Biochem. 72:1976;248-254.
22. Laemmli UK. Cleavage of structural proteins during the assembly of the bacteriophage T4. Nature. 227:1970;680-685.
23. Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA. 76:1979;4350-4354.
24. Fiedler K, Parton RG, Kellner R, Etzold T, Simons K. VIP36, a novel component of glycolipid rafts and exocytic carrier vesicles in epithelial cells. EMBO J. 13:1994;1729-1740.
25. Oliver JM. Cell biology of leukocyte abnormalities - membrane and cytoskeletal function in normal and defective cells. Am J Pathol. 93:1978;221-259.
26. Gabbiani G, Ryan GB, Lamelin JP, Vassalli P, Majno P, Bouvier CA, Cruchaud A, Lüscher EF. Human smooth muscle autoantibody. Its identification as anti-actin antibody and a study of binding to "non-muscular" cells. Am J Pathol. 72:1973;473-488.
27. Lidman K, Biberfeld G, Fragraeus A, Norberg R, Torstensson R, Utter G. Anti-actin specificity of human smooth muscle antibodies in chronic active hepatitis. Clin Exp Immunol. 24:1976;266-272.
28. Anderson P, Small JV, Sobieszek A. Studies on the specificity of smooth-muscle antibodies. Clin Exp Immunol. 26:1976;57-66.
29. Kurki P, Virtanen I. The detection of human antibodies against cytoskeltal components. J Immunol Meth. 67:1984;209-223.
30. Dighiero G, Hart S, Lim A, Borche L, Levy R, Miller RA. Autoantibody activity of immunoglobulins isolated from B-cell follicular lynmphomas. Blood. 3:1991;581-585.
31. Fragraeus A, Lidman K, Biberfeld G. Reaction of human smooth muscle antibodies with human blood lymphocytes and lymphoid cell lines. Nature. 252:1974;246.
32. Dighiero G, Lymberi P, Monot C, Abuaf N. Sera with high levels of anti-smooth muscle and anti-mitochondrial antibodies frequently bind to cytoskeleton proteins. Clin Exp Immunol. 82:1990;52-66.
33. Wächter B, Kyriatsoulis A, Lohse AW, Gerken G, Meyer zum Büschenfelde K-H, Manns M. Characterization of liver cytokeratin as a major target antigen of anti-SLA antibodies. J Hepatol. 11:1990;232-239.
34. Smillie LB. Structure and functions of tropomyosins from muscle and non-muscle sources. Trends Biochem Sci. 4:1979;151-155.
35. Zhao MH, Jones SJ, Lockwood CM. Bactericidal/permeability-increasing protein (BPI) is an important antigen for anti-neutrophil cytoplasmic autoantibodies (ANCA) in vasculitis. Clin Exp Immunol. 99:1995;49-56.