Glucose metabolism in identical twins discordant for obesity. The critical role of visceral fat

Journal of Clinical Endocrinology and Metabolism

Volumn 82, Issue 2, 1997, Pages 383-387

  Rönnemaa, Tapani ^a   Koskenvuo, Markku ^a   Marniemi, Jukka ^b   Koivunen, Terhi ^a   Sajantila, Antti ^c   Rissanen, Aila ^d   Kaitsaari, Merja ^b   Bouchard, Claude ^e   Kaprio, Jaakko ^c  

^a UNIVERSITY OF TURKU   (Finland)

^b SOCIAL INSURANCE INSTITUTION   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

^d HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^e UNIVERSITÉ LAVAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; AREA UNDER THE CURVE; ARTICLE; BODY FAT; BODY MASS; BODY WEIGHT; CHILD; FEMALE; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; HUMAN; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; TWIN DISCORDANCE;

ADIPOSE TISSUE; ADULT; BODY COMPOSITION; BODY MASS INDEX; FEMALE; GLUCOSE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OBESITY; TWINS, MONOZYGOTIC; VISCERA;

EID: 0031014894     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.82.2.383     Document Type: Article

References (24)

1. Knowler WC, Pettit DJ, Savage PJ, Bennett PH. 1981 Diabetes incidence in Pima Indians: contributions of obesity and parental diabetes. Am J Epidemiol. 113:144-156.
2. Kissebah A, Vydelingum N, Murray R, et al. 1982 Relation of body fat distribution to metabolic complications of obesity. J Clin Endocrinol Metab. 54:254-260.
3. Evans DJ, Hoffmann RG, Kalkhoff RK, Kissebah AH. 1984 Relationship of body fat topography to insulin sensitivity and metabolic profiles in premenopausal women. Metabolism. 33:68-75.
4. Björntorp P. 1990 "Portal" adipose tissue as a generator of risk factors for cardiovascular disease and diabetes. Arteriosclerosis. 10:493-496.
5. Young TK, Gelskey DE. 1995 Is noncentral obesity metabolically benign? Implications for prevention from a population survey. JAMA 274:1939-1941.
6. Abate N, Garg A, Peshock RM, Stray-Gundersen J, Grundy SM. 1995 Relationships of generalized and regional adiposity to insulin sensitivity in men. J Clin Invest. 96:88-98.
7. Bouchard C. 1995 Genetics and the metabolic syndrome. Int J Obes. [Suppl 1]19:S52-S59.
8. Kaprio J, Sarna S, Koskenvuo M, Rantasalo I. 1978 The Finnish twin registry: formation and compilation, questionnaire study, zygosity determination procedures and research program. Prog Clin Biol Res. 248:179-184.
9. Sarna S, Kaprio J, Sistonen P, Koskenvuo M. 1978 Diagnosis of twin zygosity by mailed questionnaire. Hum Hered. 28:241-254.
10. Smith SM, Penrose LS. 1955 Monozygotic and dizygotic twin analysis. Ann Hum Genet. 19:273-289.
11. Reed T. 1986 Blind assessment of zygosity using dermatoglyphics from the NHLBI twin study. American Dermatoglyphics Association Newsletter. 5:6-11.
12. Cederholm J, Wibell L. 1990 Insulin release and peripheral sensitivity at the oral glucose tolerance test. Diabetes Res Clin Pract. 10:167-175.
13. Siri WE. 1956 The gross composition of the body. In: Lawrence JH, Tobias CA, eds. Advances in biological and medical physics, Vol 4. New York: Academic; 239-280.
14. Staten MA, Totty WG, Kohrt WM. 1989 Measurement of fat distribution by magnetic resonance imaging. Invest Radiol. 24:345-349.
15. Despres J-P, Moorjani S, Lupien PJ, Tremblay A, Nadeau A, Bouchard C. 1990 Regional distribution of body fat, plasma lipoproteins, and cardiovascular disease. Arteriosclerosis. 10:497-511.
16. Sparrow D, Borkan GA, Gerzof SG, Wisniewski C, Silbert CK. 1986 Relationship of fat distribution to glucose tolerance. Results of computed tomography in male participants of the Normative Aging Study. Diabetes. 35:411-415.
17. DeFronzo RA, Tobin JD, Andres R. 1979 Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol. 237:E214-E223.
18. Laakso M. How good a marker is insulin level for insulin resistance? 1993 Am J Epidemiol. 137:959-965.
19. Terry JG, Hinson WH, Evans GW, Schreiner PJ, Hagaman AP, Crouse JR. 1995 Evaluation of magnetic resonance imaging for quantification of intraabdominal fat in human beings by spin-echo and inversion-recovery protocols. Am J Clin Nutr. 62:297-301.
20. Facchini FS, Hollenbeck CB, Jeppesen J, Chen Y-DI, Reaven GM. 1992 Insulin resistance and cigarette smoking. Lancet. 339:1128-1130.
21. Shimokata H, Muller DC, Andres R. 1989 Studies in the distribution of body fat. III. Effects of cigarette smoking. JAMA 261:1169-1173.
22. Randle P, Garland P, Hales C, Newsholme E. 1963 The glucose fatty acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet. 1:785-789.
23. Kissebah AH, Krakower GR. 1994 Regional obesity and morbidity. Physiol Rev. 74:761-811.
24. Kissebah AH, Peiris AN. 1989 Biology of regional body fat distribution: relationship to non-insulin-dependent diabetes mellitus. Diabetes Metab Rev. 5:83-109.