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Volumn 142, Issue 1, 1997, Pages 123-132

In vitro metabolism of 7,12-dimethylbenz[a]anthracene by rainbow trout liver microsomes and trout P450 isoforms

Author keywords

[No Author keywords available]

Indexed keywords

BETA NAPHTHOFLAVONE; CYTOCHROME P450 ISOENZYME; DIMETHYLBENZ[A]ANTHRACENE; ISOSAFROLE;

EID: 0031014890     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1996.8021     Document Type: Article
Times cited : (12)

References (53)
  • 1
    • 0028227327 scopus 로고
    • Two unique CYP1 genes are expressed in response to 3-methylcholanthrene treatment in rainbow trout
    • Berndtson, A. K., and Chen, T. T. (1994). Two unique CYP1 genes are expressed in response to 3-methylcholanthrene treatment in rainbow trout. Arch. Biochem. Biophys. 310, 187-195.
    • (1994) Arch. Biochem. Biophys. , vol.310 , pp. 187-195
    • Berndtson, A.K.1    Chen, T.T.2
  • 2
    • 0029009343 scopus 로고
    • Identification of a rat adrenal cytochrome P450 active in polycyclic hydrocarbon metabolism as rat CYP1B1. Demonstration of a unique tissue-specific pattern of hormonal and aryl hydrocarbon receptor-linked regulation
    • Bhattacharyya, K. K., Brake, P. B., Eltom, S. E., Otto, S. A., and Jefcoate, C. R. (1995). Identification of a rat adrenal cytochrome P450 active in polycyclic hydrocarbon metabolism as rat CYP1B1. Demonstration of a unique tissue-specific pattern of hormonal and aryl hydrocarbon receptor-linked regulation. J. Biol. Chem. 270, 11595-11602.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11595-11602
    • Bhattacharyya, K.K.1    Brake, P.B.2    Eltom, S.E.3    Otto, S.A.4    Jefcoate, C.R.5
  • 3
    • 0021042171 scopus 로고
    • Products of binding of 7,12-dimethylbenz(a)anthracene to DNA in mouse skin
    • Bigger, C. A., Sawicki, J. T., Blake, D. M., Raymond, L. J., and Dipple, A. (1983). Products of binding of 7,12-dimethylbenz(a)anthracene to DNA in mouse skin. Cancer Res. 43, 5647-5651.
    • (1983) Cancer Res. , vol.43 , pp. 5647-5651
    • Bigger, C.A.1    Sawicki, J.T.2    Blake, D.M.3    Raymond, L.J.4    Dipple, A.5
  • 4
    • 0027990221 scopus 로고
    • Cloning and sequencing of the major rainbow trout constitutive cytochrome P450 (CYP2K1). Identification of a new cytochrome P450 gene subfamily and its expression in mature rainbow trout liver and trunk kidney
    • Buhler, D. R., Yang, Y.-H., Dreher, T. W., Miranda, C. L., and Wang, J.-L. (1994). Cloning and sequencing of the major rainbow trout constitutive cytochrome P450 (CYP2K1). Identification of a new cytochrome P450 gene subfamily and its expression in mature rainbow trout liver and trunk kidney. Arch. Biochem. Biophys. 312, 45-51.
    • (1994) Arch. Biochem. Biophys. , vol.312 , pp. 45-51
    • Buhler, D.R.1    Yang, Y.-H.2    Dreher, T.W.3    Miranda, C.L.4    Wang, J.-L.5
  • 5
    • 0019551730 scopus 로고
    • Western blotting: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A
    • Burnette, W. N. (1981). Western blotting: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal. Biochem. 112, 195-203.
    • (1981) Anal. Biochem. , vol.112 , pp. 195-203
    • Burnette, W.N.1
  • 6
    • 0029080079 scopus 로고
    • Central role of radical cations in metabolic activation of polycyclic aromatic hydrocarbons
    • Cavalieri, E. L., and Rogan, E. G. (1995). Central role of radical cations in metabolic activation of polycyclic aromatic hydrocarbons. Xenobiotica 25, 677-688.
    • (1995) Xenobiotica , vol.25 , pp. 677-688
    • Cavalieri, E.L.1    Rogan, E.G.2
  • 7
    • 34249923850 scopus 로고
    • Catalytic activity and immunochemical quantification of hepatic cytochrome P-450 in β-naphthoflavone and isosafrole treated rainbow trout (Oncorhynchus mykiss)
    • Celander, M., and Forlin, L. (1991). Catalytic activity and immunochemical quantification of hepatic cytochrome P-450 in β-naphthoflavone and isosafrole treated rainbow trout (Oncorhynchus mykiss). Fish Physiol. Biochem. 9, 189-197.
    • (1991) Fish Physiol. Biochem. , vol.9 , pp. 189-197
    • Celander, M.1    Forlin, L.2
  • 8
    • 0000092722 scopus 로고    scopus 로고
    • Immunochemical comparison of constitutively expressed cytochrome P450 (CYP) isoforms from different teleost fish species and their relatedness to human CYP3A4
    • Celander, M., Buhler, D. R., Forlin, L., Goksoyr, A., Miranda, C. L., Woodin, B. R., and Stegeman, J. J. (1996). Immunochemical comparison of constitutively expressed cytochrome P450 (CYP) isoforms from different teleost fish species and their relatedness to human CYP3A4. Fish Physiol. Biochem., 15, 323-332.
    • (1996) Fish Physiol. Biochem. , vol.15 , pp. 323-332
    • Celander, M.1    Buhler, D.R.2    Forlin, L.3    Goksoyr, A.4    Miranda, C.L.5    Woodin, B.R.6    Stegeman, J.J.7
  • 9
    • 0023696110 scopus 로고
    • A metabolite of the carcinogen 7,12-dimethylbenz[a]anthracene that reacts predominantly with adenine residues in DNA
    • Cheng, S. C., Prakash, A. S., Pigott, M. A., Hilton, B. D., Lee, H., Harvey, R. G., and Dipple, A. (1988a). A metabolite of the carcinogen 7,12-dimethylbenz[a]anthracene that reacts predominantly with adenine residues in DNA. Carcinogenesis 9, 1721-1723.
    • (1988) Carcinogenesis , vol.9 , pp. 1721-1723
    • Cheng, S.C.1    Prakash, A.S.2    Pigott, M.A.3    Hilton, B.D.4    Lee, H.5    Harvey, R.G.6    Dipple, A.7
  • 11
    • 0019435706 scopus 로고
    • Metabolism of 7,12-dimethylbenz(a)anthracene and 7-hydroxymethyl-12-methylbenz(a)anthracene by rat liver nuclei and microsomes
    • Chou, M. W., Yang, S. K., Sydor, W., and Yang, C. S. (1981). Metabolism of 7,12-dimethylbenz(a)anthracene and 7-hydroxymethyl-12-methylbenz(a)anthracene by rat liver nuclei and microsomes. Cancer Res. 41, 1559-1564.
    • (1981) Cancer Res. , vol.41 , pp. 1559-1564
    • Chou, M.W.1    Yang, S.K.2    Sydor, W.3    Yang, C.S.4
  • 12
    • 0018689031 scopus 로고
    • The initiation of tumors on mouse skin by dihydrodiols derived from 7,12-dimethylbenz[a]anthracene and 3-methylcholanthrene
    • Chouroulinkov, I., Gentil, A., Tierney, B., Grover, P. L., and Sims, P. (1979). The initiation of tumors on mouse skin by dihydrodiols derived from 7,12-dimethylbenz[a]anthracene and 3-methylcholanthrene. Int. J. Cancer 24, 455-460.
    • (1979) Int. J. Cancer , vol.24 , pp. 455-460
    • Chouroulinkov, I.1    Gentil, A.2    Tierney, B.3    Grover, P.L.4    Sims, P.5
  • 13
    • 84968992894 scopus 로고
    • The role of constitutive rat liver cytochromes P-450 in the metabolic activation of 7,12-dimethylbenz[a]anthracene
    • Christou, M., Janovich, M. C., Ryan, D. E., Thomas, P. E., Levin, W., and Jefcoate, C. R. (1987). The role of constitutive rat liver cytochromes P-450 in the metabolic activation of 7,12-dimethylbenz[a]anthracene. Proc. Am. Assoc. Cancer Res. 28, 132.
    • (1987) Proc. Am. Assoc. Cancer Res. , vol.28 , pp. 132
    • Christou, M.1    Janovich, M.C.2    Ryan, D.E.3    Thomas, P.E.4    Levin, W.5    Jefcoate, C.R.6
  • 14
    • 0024366078 scopus 로고
    • Epoxide hydratase: Sex specific expression and rate-limiting role in DMBA metabolism
    • Christou, M., Jovanovich, M. C., and Jefcoate, C. R. (1989). Epoxide hydratase: Sex specific expression and rate-limiting role in DMBA metabolism. Carcinogenesis 10, 1883-1890.
    • (1989) Carcinogenesis , vol.10 , pp. 1883-1890
    • Christou, M.1    Jovanovich, M.C.2    Jefcoate, C.R.3
  • 15
    • 0026597891 scopus 로고
    • Selective suppression of the catalytic activity of cDNA-expressed cytochrome P4502B1 toward polycyclic hydrocarbons in the microsomal membrane: Modification of this effect by specific amino acid substitutions
    • Christou, M., Mitchell, M. J., Aoyama, T., Gelboin, H. V., Gonzalez, F. J., and Jefcoate, C. R. (1992). Selective suppression of the catalytic activity of cDNA-expressed cytochrome P4502B1 toward polycyclic hydrocarbons in the microsomal membrane: Modification of this effect by specific amino acid substitutions. Biochemistry 31, 2835-2841.
    • (1992) Biochemistry , vol.31 , pp. 2835-2841
    • Christou, M.1    Mitchell, M.J.2    Aoyama, T.3    Gelboin, H.V.4    Gonzalez, F.J.5    Jefcoate, C.R.6
  • 16
    • 0024790819 scopus 로고
    • Metabolic activation of 7,12-dimethylbenz[a]anthracene: Role of cytochrome P-450 isoenzymes in the formation of DNA and protein adducts in vitro
    • Cusack, M., Burnett, A. K., Morrison, V. M., and Craft, J. A. (1989). Metabolic activation of 7,12-dimethylbenz[a]anthracene: Role of cytochrome P-450 isoenzymes in the formation of DNA and protein adducts in vitro. Biochem. Soc. Trans. 17, 1014-1015.
    • (1989) Biochem. Soc. Trans. , vol.17 , pp. 1014-1015
    • Cusack, M.1    Burnett, A.K.2    Morrison, V.M.3    Craft, J.A.4
  • 17
    • 0022815366 scopus 로고
    • Specific activation of the cellular Harvey-ras oncogene in 7,12-dimethylbenz(a)anthracene-induced mouse mammary tumors
    • Dandekar, S., Sukumar, S., Zarbl, H., Young, L. J. T., and Cardiff, R. D. (1986). Specific activation of the cellular Harvey-ras oncogene in 7,12-dimethylbenz(a)anthracene-induced mouse mammary tumors. Mol. Cell. Biol. 6, 4104-4108.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 4104-4108
    • Dandekar, S.1    Sukumar, S.2    Zarbl, H.3    Young, L.J.T.4    Cardiff, R.D.5
  • 18
    • 0017794226 scopus 로고
    • Radioactive assay of aryl hydrocarbon hydroxylase monooxygenase and epoxide hydrolase
    • DePierre, J. W., Johannessen, K. A. M., Moron, M. S., and Seidegard, J. (1978). Radioactive assay of aryl hydrocarbon hydroxylase monooxygenase and epoxide hydrolase. Methods Enzymol. 52C, 412-418.
    • (1978) Methods Enzymol. , vol.52 C , pp. 412-418
    • DePierre, J.W.1    Johannessen, K.A.M.2    Moron, M.S.3    Seidegard, J.4
  • 19
    • 0027263936 scopus 로고
    • Carcinogenicity, metabolism and Ki-ras proto-oncogene activation by 7,12-dimethylbenz[a]anthracene in rainbow trout embryos
    • Fong, A. T., Dashwood, R. H., Cheng, R., Mathews, C., Ford, B., Hendricks, J. D., and Bailey, G. S. (1993). Carcinogenicity, metabolism and Ki-ras proto-oncogene activation by 7,12-dimethylbenz[a]anthracene in rainbow trout embryos. Carcinogenesis 14, 629-635.
    • (1993) Carcinogenesis , vol.14 , pp. 629-635
    • Fong, A.T.1    Dashwood, R.H.2    Cheng, R.3    Mathews, C.4    Ford, B.5    Hendricks, J.D.6    Bailey, G.S.7
  • 20
    • 0023156272 scopus 로고
    • Evidence for a free-radical-dependent metabolism of 7,12-dimethylbenz(a)anthracene in rat testis
    • Georgellis, A., Montelius, J., and Rydstrom, J. (1987). Evidence for a free-radical-dependent metabolism of 7,12-dimethylbenz(a)anthracene in rat testis. Toxicol. Appl. Pharmacol. 87, 141-154.
    • (1987) Toxicol. Appl. Pharmacol. , vol.87 , pp. 141-154
    • Georgellis, A.1    Montelius, J.2    Rydstrom, J.3
  • 21
    • 4243500704 scopus 로고    scopus 로고
    • β-Naphthoflavone induces CYP1A1 and CYP1A3 proteins in the liver of rainbow trout (Oneorhyneus mykiss)
    • in press
    • Gooneratne, R., Miranda, C. L., Henderson, M. C., and Buhler, D. R. (1996). β-Naphthoflavone induces CYP1A1 and CYP1A3 proteins in the liver of rainbow trout (Oneorhyneus mykiss), Xenobiotica, in press.
    • (1996) Xenobiotica
    • Gooneratne, R.1    Miranda, C.L.2    Henderson, M.C.3    Buhler, D.R.4
  • 22
    • 0028351406 scopus 로고
    • Use of alkoxyphenoxazones, 7-alkoxycoumarins and 7-alkoxyquinolines as fluorescent substrates for rainbow trout hepatic microsomes after treatment with various inducers
    • Haasch, M. L., Graf, W. K., Quardokus, E. M., Mayer, R. T., and Lech, J. J. (1994). Use of alkoxyphenoxazones, 7-alkoxycoumarins and 7-alkoxyquinolines as fluorescent substrates for rainbow trout hepatic microsomes after treatment with various inducers. Biochem. Pharmacol. 47, 893-903.
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 893-903
    • Haasch, M.L.1    Graf, W.K.2    Quardokus, E.M.3    Mayer, R.T.4    Lech, J.J.5
  • 24
    • 0023765161 scopus 로고
    • Trout P4501A1: cDNA and deduced protein sequence, expression in liver, and evolutionary significance
    • Heilmann, L. J., Sheen, Y. Y., Bigelow, S. W., and Nebert, D. W. (1988). Trout P4501A1: cDNA and deduced protein sequence, expression in liver, and evolutionary significance. DNA 7, 379-387.
    • (1988) DNA , vol.7 , pp. 379-387
    • Heilmann, L.J.1    Sheen, Y.Y.2    Bigelow, S.W.3    Nebert, D.W.4
  • 25
    • 0025862334 scopus 로고
    • The role of specific cytochromes P450 in the formation of 7,12-dimethylbenz(a)anthracene-protein adducts in rat liver microsomes in vitro
    • Lambard, S. E., Burnett, A. K., Wolf, C. R., and Craft, J. A. (1991). The role of specific cytochromes P450 in the formation of 7,12-dimethylbenz(a)anthracene-protein adducts in rat liver microsomes in vitro. Biochem. Pharmacol. 42, 1529-1535.
    • (1991) Biochem. Pharmacol. , vol.42 , pp. 1529-1535
    • Lambard, S.E.1    Burnett, A.K.2    Wolf, C.R.3    Craft, J.A.4
  • 26
    • 0028406868 scopus 로고
    • Inhibition studies on the involvement of flavoprotein reductase in menadione-and nitrofurantoin-stimulated oxyradical production by hepatic microsomes of flounder (Platichthys flesus)
    • Lemaire, P., and Livingstone, D. R. (1994). Inhibition studies on the involvement of flavoprotein reductase in menadione-and nitrofurantoin-stimulated oxyradical production by hepatic microsomes of flounder (Platichthys flesus). J. Biochem. Toxicol. 9, 87-95.
    • (1994) J. Biochem. Toxicol. , vol.9 , pp. 87-95
    • Lemaire, P.1    Livingstone, D.R.2
  • 27
    • 0028207093 scopus 로고
    • Dietary selenite modifies glutathione metabolism and 7,12-dimethylbenz(a)anthracene conjugation in rats
    • Liu, J. Z., Zhang, B. Z., and Milner, J. A. (1994). Dietary selenite modifies glutathione metabolism and 7,12-dimethylbenz(a)anthracene conjugation in rats. J. Nutr. 124, 172-180.
    • (1994) J. Nutr. , vol.124 , pp. 172-180
    • Liu, J.Z.1    Zhang, B.Z.2    Milner, J.A.3
  • 30
    • 0023747133 scopus 로고
    • Role of specific P-450 isoenzymes in the regio-selective metabolism of 7,12-dimethylbenz[a]anthracene in microsomes from rats treated with phenobarbital or Sudan III
    • McCord, A., Burnett, A. K., Wolf, C. R., Morrison, V., and Craft, J. A. (1988). Role of specific P-450 isoenzymes in the regio-selective metabolism of 7,12-dimethylbenz[a]anthracene in microsomes from rats treated with phenobarbital or Sudan III. Carcinogenesis 9, 1485-1491.
    • (1988) Carcinogenesis , vol.9 , pp. 1485-1491
    • McCord, A.1    Burnett, A.K.2    Wolf, C.R.3    Morrison, V.4    Craft, J.A.5
  • 31
    • 0024497781 scopus 로고
    • Purification and characterization of hepatic steroid hydroxylases from untreated rainbow trout
    • Miranda, C. L., Wang, J.-L., Henderson, M. C., and Buhler, D. R. (1989). Purification and characterization of hepatic steroid hydroxylases from untreated rainbow trout. Arch. Biochem. Biophys. 268, 227-238.
    • (1989) Arch. Biochem. Biophys. , vol.268 , pp. 227-238
    • Miranda, C.L.1    Wang, J.-L.2    Henderson, M.C.3    Buhler, D.R.4
  • 32
    • 0025793496 scopus 로고
    • Comparison of rainbow trout and mammalian cytochrome P450 enzymes. Evidence for structural similarity between trout P450 LMC5 and human P450IIIA4
    • Miranda, C. L., Wang, J.-L., Henderson, M. C., Zhao, X., Guengerich, F. P., and Buhler, D. R. (1991). Comparison of rainbow trout and mammalian cytochrome P450 enzymes. Evidence for structural similarity between trout P450 LMC5 and human P450IIIA4. Biochem. Biophys. Res. Commun. 176, 558-563.
    • (1991) Biochem. Biophys. Res. Commun. , vol.176 , pp. 558-563
    • Miranda, C.L.1    Wang, J.-L.2    Henderson, M.C.3    Zhao, X.4    Guengerich, F.P.5    Buhler, D.R.6
  • 33
    • 0011363635 scopus 로고    scopus 로고
    • Evaluation of chemicals as inhibitors of trout P450s
    • Miranda, C. L., Henderson, M. C., and Buhler, D. R. (1996). Evaluation of chemicals as inhibitors of trout P450s. Toxicologist 30, 275.
    • (1996) Toxicologist , vol.30 , pp. 275
    • Miranda, C.L.1    Henderson, M.C.2    Buhler, D.R.3
  • 34
    • 0025959365 scopus 로고
    • Metabolism of 7,12-dimethylbenz[a]anthracene in hepatic microsomal membranes from rats treated with isoenzyme-selective inducers of cytochrome P450
    • Morrison, V. M., Burnett, A. K., and Craft, J. A. (1991a). Metabolism of 7,12-dimethylbenz[a]anthracene in hepatic microsomal membranes from rats treated with isoenzyme-selective inducers of cytochrome P450. Biochem. Pharmacol. 41, 1505-1512.
    • (1991) Biochem. Pharmacol. , vol.41 , pp. 1505-1512
    • Morrison, V.M.1    Burnett, A.K.2    Craft, J.A.3
  • 35
    • 0025871501 scopus 로고
    • The contribution of specific cytochrome P-450 in the metabolism of 7,12-dimethylbenz[a]anthracene in rat and human liver microsomal membranes
    • Morrison, V. M., Burnett, A. K., Forrester, L. M., Wolf, C. R., and Craft, J. A. (1991b). The contribution of specific cytochrome P-450 in the metabolism of 7,12-dimethylbenz[a]anthracene in rat and human liver microsomal membranes. Chem.-Biol. Interact. 79, 179-196.
    • (1991) Chem.-biol. Interact. , vol.79 , pp. 179-196
    • Morrison, V.M.1    Burnett, A.K.2    Forrester, L.M.3    Wolf, C.R.4    Craft, J.A.5
  • 37
    • 78651165715 scopus 로고
    • The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
    • Omura, T., and Sato, R. (1964). The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J. Biol. Chem. 239, 2370-2378.
    • (1964) J. Biol. Chem. , vol.239 , pp. 2370-2378
    • Omura, T.1    Sato, R.2
  • 38
    • 0026485625 scopus 로고
    • Polycyclic aromatic hydrocarbon metabolism in rat adrenal, ovary, and testis microsomes is catalyzed by the same novel cytochrome P450 (P450RAP)
    • Otto, S., Bhattacharyya, K. K., and Jefcoate, C. R. (1992). Polycyclic aromatic hydrocarbon metabolism in rat adrenal, ovary, and testis microsomes is catalyzed by the same novel cytochrome P450 (P450RAP). Endocrinology 131, 3067-3076.
    • (1992) Endocrinology , vol.131 , pp. 3067-3076
    • Otto, S.1    Bhattacharyya, K.K.2    Jefcoate, C.R.3
  • 40
    • 0028339108 scopus 로고
    • Mouse cytochrome P-450EF, representative of a new 1B subfamily of cytochrome P-450s. Cloning, sequence determination, and tissue expression
    • Savas, U., Bhattacharyya, K. K., Christou, M., Alexander, D. L., and Jefcoate, C. R. (1994). Mouse cytochrome P-450EF, representative of a new 1B subfamily of cytochrome P-450s. Cloning, sequence determination, and tissue expression. J. Biol. Chem. 269, 14905-14911.
    • (1994) J. Biol. Chem. , vol.269 , pp. 14905-14911
    • Savas, U.1    Bhattacharyya, K.K.2    Christou, M.3    Alexander, D.L.4    Jefcoate, C.R.5
  • 41
    • 0020630061 scopus 로고
    • Involvement of both syn and anti-dihydrodiol-epoxides in the binding of 7,12-dimethylbenz(a)anthracene to DNA in mouse embryo cell culture
    • Sawicki, J. T., Moschel, R. C., and Dipple, A. (1983). Involvement of both syn and anti-dihydrodiol-epoxides in the binding of 7,12-dimethylbenz(a)anthracene to DNA in mouse embryo cell culture. Cancer Res. 43, 3212-3218.
    • (1983) Cancer Res. , vol.43 , pp. 3212-3218
    • Sawicki, J.T.1    Moschel, R.C.2    Dipple, A.3
  • 42
    • 0026649236 scopus 로고
    • In vivo DNA/RNA adduction of 7,12-dimethylbenz(a)anthracene (DMBA) and benzo(a)pyrene (BaP) in the liver of rainbow trout (Oncorhynchus tnykiss)
    • Schnitz, A. R., and O'Connor, J. M. (1992). In vivo DNA/RNA adduction of 7,12-dimethylbenz(a)anthracene (DMBA) and benzo(a)pyrene (BaP) in the liver of rainbow trout (Oncorhynchus tnykiss). J. Environ. Pathol. Toxicol. Oncol. 11, 229-233.
    • (1992) J. Environ. Pathol. Toxicol. Oncol. , vol.11 , pp. 229-233
    • Schnitz, A.R.1    O'Connor, J.M.2
  • 43
    • 0027250588 scopus 로고
    • Time-varying conjugation of 7,12-dimethylbenz[a]anthracene metabolites in rainbow trout (Oncorhynchus mykiss)
    • Schnitz, A. R., Squibb, K. S., and O'Connor, J. M. (1993). Time-varying conjugation of 7,12-dimethylbenz[a]anthracene metabolites in rainbow trout (Oncorhynchus mykiss). Toxicol. Appl. Pharmacol. 121, 58-70.
    • (1993) Toxicol. Appl. Pharmacol. , vol.121 , pp. 58-70
    • Schnitz, A.R.1    Squibb, K.S.2    O'Connor, J.M.3
  • 44
    • 0028111994 scopus 로고
    • cDNA cloning, sequence analysis, and induction by aryl hydrocarbons of a murine cytochrome P450 gene, CYP1B1
    • Shen, Z., Liu, J., Wells, R. L., and Elkind, M. M. (1994). cDNA cloning, sequence analysis, and induction by aryl hydrocarbons of a murine cytochrome P450 gene, CYP1B1. DNA Cell. Biol. 13, 763-769.
    • (1994) DNA Cell. Biol. , vol.13 , pp. 763-769
    • Shen, Z.1    Liu, J.2    Wells, R.L.3    Elkind, M.M.4
  • 45
    • 0024326433 scopus 로고
    • Roles of individual cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons
    • Shimada, T., Martin, M. V., Pruess-Schwartz, D., Marnett, L. J., and Guengerich, F. P. (1989). Roles of individual cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons. Cancer Res. 49, 6304-6312.
    • (1989) Cancer Res. , vol.49 , pp. 6304-6312
    • Shimada, T.1    Martin, M.V.2    Pruess-Schwartz, D.3    Marnett, L.J.4    Guengerich, F.P.5
  • 46
    • 0001340592 scopus 로고
    • Involvement of dihydrodiols and diol epoxides in the metabolic activation of polycyclic hydrocarbons other than benzo[a]pyrene
    • H. V. Gelboin and P. O. P. Ts'o, Eds., Academic Press, New York
    • Sims, P., and Grover, P. L. (1981). Involvement of dihydrodiols and diol epoxides in the metabolic activation of polycyclic hydrocarbons other than benzo[a]pyrene. In Polycyclic Hydrocarbons and Cancer (H. V. Gelboin and P. O. P. Ts'o, Eds.), Vol. 3, pp. 117-181. Academic Press, New York.
    • (1981) Polycyclic Hydrocarbons and Cancer , vol.3 , pp. 117-181
    • Sims, P.1    Grover, P.L.2
  • 47
    • 84886639245 scopus 로고
    • Metabolic activation of 7,12-dimethylbenz[a]-anthracene in rat mammary tissue: Fluorescence spectral characteristics of hydrocarbon DNA-adducts
    • Vigny, P., Brunissen, A., Phillips, D. H., Cooper, C. S., Hewer, A., Grover, P. L., and Sims, P. (1985). Metabolic activation of 7,12-dimethylbenz[a]-anthracene in rat mammary tissue: Fluorescence spectral characteristics of hydrocarbon DNA-adducts. Cancer Lett. 26, 51-59.
    • (1985) Cancer Lett. , vol.26 , pp. 51-59
    • Vigny, P.1    Brunissen, A.2    Phillips, D.H.3    Cooper, C.S.4    Hewer, A.5    Grover, P.L.6    Sims, P.7
  • 48
    • 0029048701 scopus 로고
    • Rat CYP1B1: An adrenal cytochrome P450 that exhibits sex-dependent expression in livers and kidneys of TCDD-treated animals
    • Walker, N. J., Gastel, J. A., Costa, L. T., Clark, G. C., Lucier, G. W., and Sutter, T. R. (1995). Rat CYP1B1: An adrenal cytochrome P450 that exhibits sex-dependent expression in livers and kidneys of TCDD-treated animals. Carcinogenesis 16, 1319-1327.
    • (1995) Carcinogenesis , vol.16 , pp. 1319-1327
    • Walker, N.J.1    Gastel, J.A.2    Costa, L.T.3    Clark, G.C.4    Lucier, G.W.5    Sutter, T.R.6
  • 49
    • 0021676766 scopus 로고
    • Benzo[a]pyrene-hydroxylase catalyzed by purified isozymes of cytochrome P-450 from β-naphthofla-vone-fed rainbow trout
    • Williams, D. E., and Buhler, D. R. (1984). Benzo[a]pyrene-hydroxylase catalyzed by purified isozymes of cytochrome P-450 from β-naphthofla-vone-fed rainbow trout. Biochem. Pharmacol. 33, 3743-3753.
    • (1984) Biochem. Pharmacol. , vol.33 , pp. 3743-3753
    • Williams, D.E.1    Buhler, D.R.2
  • 50
    • 0021749950 scopus 로고
    • Binding and metabolism of benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene by seven purified forms of cytochrome P450
    • Wilson, N. M., Christou, M., Turner, C. R., Wrighton, S. A., and Jefcoate, C. R. (1984). Binding and metabolism of benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene by seven purified forms of cytochrome P450. Carcinogenesis 5, 1475-1483.
    • (1984) Carcinogenesis , vol.5 , pp. 1475-1483
    • Wilson, N.M.1    Christou, M.2    Turner, C.R.3    Wrighton, S.A.4    Jefcoate, C.R.5
  • 51
    • 0018941622 scopus 로고
    • Carcinogenicity and mutagenicity of the 3,4-dihydrodiols and other metabolites of 7,12-dimethylbenz(a)anthracene and its hydroxymethyl derivatives
    • Wislocki, P. G., Gadek, K. M., Chou, M. W., Yang, S. K., and Lu, A. Y. H. (1980). Carcinogenicity and mutagenicity of the 3,4-dihydrodiols and other metabolites of 7,12-dimethylbenz(a)anthracene and its hydroxymethyl derivatives. Cancer Res. 40, 3661-3664.
    • (1980) Cancer Res. , vol.40 , pp. 3661-3664
    • Wislocki, P.G.1    Gadek, K.M.2    Chou, M.W.3    Yang, S.K.4    Lu, A.Y.H.5
  • 53
    • 0020050337 scopus 로고
    • Metabolism and activation of aflatoxin B1 by reconstituted cytochrome P-450 system of rat liver
    • Yoshizawa, H., Uchimaru, R., Kamataki, T., Kato, R., and Ueno, Y. (1982). Metabolism and activation of aflatoxin B1 by reconstituted cytochrome P-450 system of rat liver. Cancer Res. 42, 1120-1124.
    • (1982) Cancer Res. , vol.42 , pp. 1120-1124
    • Yoshizawa, H.1    Uchimaru, R.2    Kamataki, T.3    Kato, R.4    Ueno, Y.5


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