Intracerebroventricular porcine corticotropin-releasing hormone and cortisol effects on pig immune measures and behavior

Physiology and Behavior

Volumn 61, Issue 1, 1997, Pages 15-23

  Salak Johnson, Janeen L ^a,c   McGlone, John J ^a   Whisnant, C Scott ^a   Norman, Reid L ^a   Kraeling, Robert R ^b  

^a TEXAS TECH UNIVERSITY   (United States)

^b RUSSELL RESEARCH CENTER   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Behavior Immunity; CRH; Pigs; Stress

Indexed keywords

CORTICOTROPIN RELEASING FACTOR; HYDROCORTISONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CELL COUNT; CONTROLLED STUDY; HYDROCORTISONE BLOOD LEVEL; IMMUNE RESPONSE; IMMUNE SYSTEM; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; LYMPHOCYTE; LYMPHOCYTE PROLIFERATION; NATURAL KILLER CELL; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; SWINE;

EID: 0031014575     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9384(96)00315-0     Document Type: Article

References (45)

1. Bakeman, R.; Gottman, J. M. Observing interaction: An introduction to sequential analysis. New York: Cambridge University Press, 1986.
2. Britton, D. R.; Koob, G. F.; Rivier, J.; Vale, W. Intraventricular corticotropin-releasing factor enhances behavioral effects of novelty. Life Sci. 31:363-367; 1982.
3. Britton, D. R.; Varela, M.; Garcia, A.; Rosenthal, M. Dexamethasone suppresses pituitary-adrenal but not behavioral effects of central administered CRF. Life Sci. 38:211-216; 1986.
4. Brown, M. R.; Fisher, L. A.; Spiess, J.; Rivier, C; Vale, W. Corticotropin-releasing factor: Effects on the sympathetic nervous system and oxygen consumption. Life Sci. 30:207-210; 1982.
5. Chrousos, G. P.; Loriaux, D. L.; Gold, P. W. Introduction, the concept of stress and its historical development. In: Chrousos, G. P.; Loriaux, D. L.; Gold, P. W., eds. Mechanism of physical and emotional stress. New York: Plenum Press, 1988:3-7.
6. Cunnick, J. E.; Lysle, D. T.; Armfield, A.; Rabin, B. S. Shock-induced modulation of lymphocyte responsiveness and natural killer activity: Differential mechanisms of induction. Brain Beh. Immun. 2:102-113; 1988.
7. Curtis, S. E. Guide for the care and use of agricultural animals in agricultural research and teaching. Champaign, IL: Association Headquarters, 1988.
8. Dantzer, R.; Kelley, K. W. Stress and immunity: An integrated view of relationships between the brain and the immune system. Life Sci. 44:1995-2008; 1989.
9. Dunn, A. J.; Berridge, C. W. Physiological and behavioral responses to corticotropin-releasing factor administration: Is CRF a mediator of anxiety or stress responses? Brain Res. Rev. 15:71-100; 1990.
10. Eaves, M; Britton, K. T.; Rivier, J.; Vale, W.; Koob, G. F. Effects of corticotropin releasing factor on locomotor activity in hypophy-sectomized rats. Peptides 6:923-926; 1985.
11. Esterling, B.; Rabin, B. S. Stress-induced alteration of T-lymphocyte subsets and humoral immunity in mice. Behav. Neurosci. 101:115-119; 1987.
12. Estienne, M. J.; Kesner, J. S.; Barb, C. R.; Kraeling, R. R.; Rampacek, G. B.; Estienne, C. E. Gonadotropin and prolactin secretion following intraventricular administration of morphine in gilts (43007A). PSEBM 193:92-97; 1990.
13. Fisher, L. A.; Brown, M. R. Corticotropin-releasing factor: Central nervous system and cardiovascular regulation. In: Ganten, D.; Pfaff, D., eds. Current topics in neuroendocrinology. Vol. 3. Heidelberg: Springer-Verlag, 1983:87.
14. Ghoneum, M.; Gill, G.; Assanah, P.; Stevens, W. Susceptibility of natural killer cell activity in old rats to stress. Immunology 60:461-465; 1987.
15. Irwin, M. R.; Vale, W.; Brittton, K. T. Central corticotropin-releasing factor suppresses natural killer cell cytotoxicity. Brain Behav. Immun. 1:81-87; 1987.
16. Irwin, M. R.; Hauger, L.; Brown, M.; Britton, K. T. CRF activates autonomic nervous system and reduces natural killer cell cytotoxicity. Am. J. Physiol. 255:R744-R747; 1988.
17. Irwin, M. R.; Segal, D. S.; Hauger, R. L.; Smith, T. L. Individual behavioral and neuroendocrine differences in responsiveness to audiogenic stress. Pharm. Biochem. Behav. 32:913-917; 1989.
18. Irwin, M.; Vale, W.; Rivier, C. Central corticotropin-releasing factor mediates the suppressive effect of stress on natural killer cell cytotoxicity. Endocrinology 126:2837-2844; 1990.
19. Johnson, R. W.; von Borell, E. H.; Anderson, L. L.; Kojic, L. D.; Cunnick, J. E. Intracebroventricular injection of corticotropin-releasing hormone in the pig: acute effects on behavior, adrenocorticotropin secretion and immune suppression. Endocrinology 135: 642-648; 1994.
20. Kalin, N. H.; Conder, J. C.; Shelton, S. J. Effects of synthetic ovine CRF on ACTH, cortisol and blood pressure in sheep. Peptides 4:221-3; 1983.
21. Keller, S. E.; Weiss, J. M.; Schleiffer, S. J.; Miller, N. E.; Stein, M. Suppression of immunity by stress: Effect of graded series of Stressors on lymphocyte stimulation in the rat. Science 213:1397-1399; 1981.
22. Keller, S. E.; Weiss, J. M.; Schleifer, S. J.; Miller, N. E.; Stein, M. Stress induced suppression of immunity in adrenalectomized rats. Science 221:1301-1304; 1983.
23. Keller-Wood, M. E.; Dallman, M. F. Corticosteriod inhibition of ACTH secretion. Endocr. Rev. 5:1-24; 1984.
24. Lawrence, A. B.; Rushen, J. Stereotypie animal behaviour: Fundamentals and applications to welfare. Wallingford, UK: CAB International, 1993.
25. 51Cr release assay for the determination of natural killer cell cytotoxicity. J. Nutr. Immun. 1:63-74; 1992.
26. Lundblad, J. R.; Roberts, J. L. Regulation of proopiomelanocortin gene expression in pituitary. Endo. Rev. 9:135-158; 1988.
27. McGlone, J. J.; Plancher, E. A.; Hayden, S. L. A description of micro-and mainframe-computer programs to summarize frequency, duration and sequences of behavior. Appl. Anim. Behav. Sci. 13:219-226; 1985.
28. McGlone, J. J. A quantitative ethogram of aggressive and submissive behaviors in recently regrouped pigs. J. Anim. Sci. 61:559-565; 1985.
29. McGlone, J. J.; Lumpkin, E. A.; Norman, R. L. Adrenocorticotropin stimulates natural killer cell activity. Endocrinology 129:1653-1658;1991.
30. McGlone, J. J.; Salak-Johnson, J. L.; Nicholson, R. I.; Hicks, T. Evaluation of crates and girth tethers for sows: reproductive performance, immunity, behavior and ergonomic measures. Appl. Anim. Behav. Sci. 39:297-311; 1994.
31. Morley, J. E.; Levine, A. S. Corticotropin-releasing factor, grooming and ingestive behavior. Life Sci. 31:1459-64; 1982.
32. Moynihan, J. A.; Ader, R.; Grota, L. J.; Schactman, T. R.; Cohen, N. The effects of stress on the development of immunological memory following lose-dose antigen priming in mice. Brain Behav. Immun. 4:1-12; 1990.
33. Riley, V. Psychoneuroendocrine influences on immunocompetence and neoplasia. Science 212:1100-1109; 1981.
34. Rivier, C.; Vale, W. Mediation by corticotropin releasing factor (CRF) of adenohypophysial hormone secretion. Ann. Rev. Physiol. 48:475-494; 1986.
35. Roth, J. A.; Kaeberle, M. L.; Hsu, W. H. Effects of adrenocorticotropin administration on bovine polymorphonuclear leukocyte function and lymphocyte blastogenesis. Am. J. Vet. Res. 43:412-416; 1982.
36. Roth, J. A.; Kaeberle, M. L. Suppression of neutrophil and lymphocyte function induced by a vaccinal strain of bovine diarrhea virus with and without the administration of ACTH. Am. J. Vet. Res. 44:2366-2372; 1983.
37. Salak, J. L.; McGlone, J.J.; Lyte, M. Effects of in vitro adrenocorticotrophic hormone, Cortisol and human recombinant interleukin-2 on porcine neutrophil migration and luminol-dependent chemiluminescence. Vet. Immunol. Immunopathol. 39:327-337; 1993.
38. SAS User's Guide: Statistics. Cary, NC: SAS Institute, Inc., 1988.
39. Stein, M; Keller, S. E.; Schleifer, S. J. Stress and immunomodulation: The role of depression and neuroendocrine function. J. Immunol. 135 (2 suppl):827s-833s; 1985.
40. Strausbaugh, H.; Irwin, M. Central corticotropin-releasing hormone reduces cellular immunity. Brain Behav. Immun. 6:11-17; 1992.
41. Sutton, R. E.; Koob, G. F.; Le Moal, M.; Rivier, J.; Vale, W. Corticotropin releasing factor produces behavioral activation in rats. Nature 297:331-3; 1982.
42. Swanson, L. W.; Sawchenko, P. E. Pariventricular nucleus: A site for the integration of neuroendocrines and autonomie mechanisms. Neuroendocrinology 31:410-417; 1980.
43. Udelsman, R.; Harwood, J. P.; Millan, M. A.; Chrousos, G. P.; Goldstein, D. S.; Zimlichman, R.; Catt, K. J.; Aguilera, G. Functional corticotropin releasing factor receptors in the primate peripheral sympathetic nervous system. Nature 319:147-150; 1986.
44. Vale, W.; Spiess, J.; Rivier, C.; Rivier, J. Characterization of 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin. Science 213:1394-1397; 1981.
45. Weiss, J. M.; Sundar, S. K.; Becker, K. J.; Cierpial, M. A. Behavioral and neural influences on cellular responses: Effects of stress and interleukin-1. J. Clin. Psychiatry 50 (Suppl. 5):43-53; 1989.