Lactate/H+ uptake by red blood cells during exercise alters their physical properties

European Journal of Applied Physiology and Occupational Physiology

Volumn 75, Issue 1, 1996, Pages 54-61

  Smith, John A ^a   Telford, Richard D ^b   Kolbuch Braddon, Marysia ^c   Weidemann, Maurice J ^c  

^a UNIVERSITY OF NEW ORLEANS   (United States)

^b AUSTRALIAN INSTITUTE OF SPORT   (Australia)

^c AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

Density; Exertion; Haemolysis; Lactic acid; Osmosis

Indexed keywords

HEMOGLOBIN; HYDROGEN; LACTIC ACID;

ADOLESCENT; ADULT; ARTICLE; CELL DENSITY; CONTROLLED STUDY; ERYTHROCYTE; ERYTHROCYTE FRAGILITY; ERYTHROCYTE VOLUME; EXERCISE TEST; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; LACTATE BLOOD LEVEL; MALE; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; NORMAL HUMAN; PH; PRIORITY JOURNAL;

EID: 0031014570     PISSN: 03015548     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004210050126     Document Type: Article

References (31)

1. Åstrand PO, Hultman E, Juhlin-Dannfelt A, Reynolds G (1986) Disposal of lactate during and after strenuous exercise in humans. J Appl Physiol 61:338-343
2. Beutler E, Kuhl W, West C (1982) The osmotic fragility of erythrocytes after prolonged liquid storage and after reinfusion. Blood 59:1141-1147
3. Brugnara C, Van Ha T, Tosteson DC (1989) Acid pH induces formation of dense cells in sickle erythrocytes. Blood 74:487-495
4. Brun JF, Fons C, Raynaud E, Fedou C, Orsetti A (1991) Influence of circulating lactate on blood rheology during exercise in professional football players. Rev Port Hemorheol 5:219-229
5. Buono MJ, Faucher PE (1985) Intraerythrocyte and plasma osmolality during graded exercise in humans. J Appl Physiol 58:1069-1072
6. Buono MJ, Yeager JE (1986) Intraerythrocyte and plasma lactate concentrations during exercise in humans. Eur J Appl Physiol 55:326-329
7. Davis AM (1988) Sickle-cell trait as a risk factor for sudden death in physical training (Letter). N Engl J Med 318:787
8. Dubinsky WP, Racker E (1978) The mechanism of lactate transport in human erythrocytes. J Membr Biol 44:25-36
9. Foxdal P, Sjodin B, Rudstam H, Ostman C, Ostman B, Hedenstierna G (1990) Lactate concentration differences in plasma, whole blood, capillary finger blood and erythrocytes during submaximal graded exercise in humans. Eur J Appl Physiol 61:218-222
10. Freund, H, Lonsdorfer J, Oyono-Enguelle S, Lonsdorfer A, Bogui P (1992) Lactate exchange and removal abilities in sickle cell patients and in untrained and trained healthy humans. J Appl Physiol 73:2580-2587
11. Gray AB, Smart YC, Telford RD, Weidemann MJ, Roberts TK (1992) Anaerobic exercise causes transient changes in leukocyte subsets and IL-2R expression. Med Sci Sports Exerc 24:1332-1338
12. Harris RT, Dudley GA (1989) Exercise alters the distribution of ammonia and lactate in blood. J Appl Physiol 66:313-317
13. Hogan MC, Gladden LB, Kurdak SS, Poole DC (1995) Increased [lactate] in working dog muscle reduces tension development independent of pH. Med Sci Sports Med 27:371-377
14. Juel C, Bangsbo J, Graham T, Saltin B (1990) Lactate and potassium fluxes from human skeletal muscle during and after intense, dynamic, knee extensor exercise. Acta Physiol Scand 140:147-159
15. Kodicek M (1986) Enhanced glucose consumption in erythrocytes under mechanical stress. Cell Biochem Funct 4:153-155
16. - distribution in humans during and after high-intensity exercise: role in muscle fatigue attenuation. J Appl Physiol 78:765-777
17. 13C]lactate in humans during rest and exercise. J Appl Physiol 60:232-241
18. Mohandas N, Chassis JA (1993) Red blood cell deformability, membrane material properties and shape: regulation by transmembrane, skeletal and cytosolic proteins and lipids. Semin Hematol 30:171-192
19. Sahlin K (1992) Metabolic factors in fatigue. Sports Med 13:99-107
20. Shand BI (1986) Changes in blood rheology induced by lactic acid. Proc Univ Otago Med Sch 64:71-72
21. Smith JA (1995) Exercise, training, and red blood cell turnover. Sports Med 19:9-31
22. Smith JA, Telford RD, Mason IB, Weidemann MJ (1990) Exercise, training and neutrophil microbicidal activity. Int J Sports Med 11:179-187
23. Smith JA, Baker MS, Weidemann MJ (1992) Free radical generation in hydroperoxide-treated erythrocytes monitored continuously by luminol-amplified chemiluminescence. Biochem Int 28:1009-1020
24. Smith JA, Kolbuch-Braddon M, Gillam I, Telford RD, Weidemann MJ (1995) Changes in the susceptibility of red blood cells to oxidative and osmotic stress following submaximal exercise. Eur J Appl Physiol 70:427-436
25. Stäubli M, Roessler B (1986) The mean cell volume in long distance runners. Eur J Appl Physiol 55:49-53
26. Sullivan SG, Stern A (1983) Effects of physiologic concentrations of lactate, pyruvate and ascorbate on glucose metabolism in unstressed and oxidatively stressed human red blood cells. Biochem Pharmacol 32:2891-2902
27. Tilton WM, Seaman C, Carriero D, Piomelli S (1989) Regulation of glycolysis in the erythrocyte: role of the lactate/pyruvate and NAD/NADH ratios. J Lab Clin Med 118:146-152
28. Van Beaumont W (1973) Red cell volume with changes in plasma osmolarity during maximal exercise. J Appl Physiol 35:47-50
29. Van Beaumont W, Rochelle RH (1974) Erythrocyte volume stability with plasma osmolarity changes in exercising man. Proc Soc Exp Biol Med 145:240-243
30. Van Beaumont W, Underkofler S, Van Beaumont S (1981) Erythrocyte volume, plasma volume, and acid-base changes in exercise and heat dehydration. J Appl Physiol 50:1255-1262
31. Waldenlind L, Edlund B-L, Hulling J, Karnell J, Lund F, Rosenhamer G (1988) Decreased red cell filterability in patients with acute myocardial infarction. Acta Med Scand 224:225-229