Temporal decline in filling prescriptions for terfenadine closely in time with those for either ketoconazole or erythromycin

Clinical Pharmacology and Therapeutics

Volumn 61, Issue 1, 1997, Pages 93-96

  Burkhart, Greg A ^a   Sevka, Michael J ^a   Temple, Robert ^a   Honig, Peter K ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROMYCIN; KETOCONAZOLE; TERFENADINE;

ARTICLE; CARDIOTOXICITY; DATA BASE; DRUG INFORMATION; DRUG SAFETY; PHARMACOEPIDEMIOLOGY; PHARMACY; PRESCRIPTION; PRIORITY JOURNAL; UNITED STATES;

ADOLESCENT; ADULT; AGED; ANTI-ALLERGIC AGENTS; ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; CHILD; CHILD, PRESCHOOL; ERYTHROMYCIN; FEMALE; HEALTH MAINTENANCE ORGANIZATIONS; HUMANS; INFANT; KETOCONAZOLE; MALE; MEDICAID; MICHIGAN; MIDDLE AGED; OHIO; PRESCRIPTIONS, DRUG; TERFENADINE; UNITED STATES;

EID: 0031014463     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9236(97)90185-5     Document Type: Article

References (4)

1. Monahan BP, Ferguson CL, Killeavy ES, Lloyd BK, Troy J, Cantilena LR. Torsades de pointes occurring in association with terfenadine use. JAMA 1990;264: 2788-90.
2. Honig PK, Woosley RL, Zamani K, Conner DP, Cantilena LR. Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administrations of erythromycin. Clin Pharmacol Ther 1992;52:231-8.
3. Honig PK, Wortham DC, Sarmani K, Conner DP, Mulin JC, Cantilena LR. Terfenadine-ketoconazole interaction: pharmacokinetic and electrocardiographic consequences. JAMA 1993;269:1513-8.
4. Woosley RL, Chen Y, Freiman JP, Gillis RA. Mechanism of the cardiotoxic actions of terfenadine. JAMA 1993;269:1532-6.