Beta-2-Agonists Have Antioxidant Function in vitro. 2. The Effect of Beta-2-Agonists on Oxidant-Mediated Cytotoxicity and on Superoxide Anion Generated by Human Polymorphonuclear Leukocytes

Respiration

Volumn 64, Issue 1, 1997, Pages 23-28

  Gillissen, Adrian ^a   Wickenburg, Doris ^a   van Zwoll, Dominique ^b   Schultze Werninghaus, Gerhard ^a  

^a Allergology and Sleep Medicine   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Adrenergic receptor agonist metabolism; Antioxidants; Cytotoxicity; Neutrophils; Oxidant antagonists and inhibitors; Phenols

Indexed keywords

ANTIASTHMATIC AGENT; BECLOMETASONE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; FENOTEROL; GLUTATHIONE; IPRATROPIUM BROMIDE; ISOPRENALINE; LACTATE DEHYDROGENASE; PREDNISOLONE; PROPRANOLOL; SALBUTAMOL; SUPEROXIDE; TERBUTALINE; THEOPHYLLINE;

ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CYTOTOXICITY; FEMALE; HUMAN; HUMAN CELL; MALE; NEUTROPHIL; PRIORITY JOURNAL;

ADRENERGIC BETA-AGONISTS; ANTI-ASTHMATIC AGENTS; ANTIOXIDANTS; CELL DIVISION; CELL LINE; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIUM; FEMALE; FREE RADICAL SCAVENGERS; GLUCOCORTICOIDS; HUMANS; HYDROGEN PEROXIDE; LUNG DISEASES, OBSTRUCTIVE; MALE; MIDDLE AGED; NEUTROPHILS; SUPEROXIDES;

EID: 0031014458     PISSN: 00257931     EISSN: 14230356     Source Type: Journal    
DOI: 10.1159/000196638     Document Type: Article

References (39)

1. Kainp DW, Graceffa P, Pryor WA, Weitzman SA: The role of free radicals in asbestos-induced diseases, Free Radic Biol Med 1992; 12:293-315.
2. Cantin AM, North GA, Fells RC, Hubbard RC, Crystal RG: Oxidant mediated epithelial cell injury in pulmonary fibrosis, J Clin Invest 1987;79:1665-1673.
3. Erzurum SC, Danel C, Gillissen A, Chu C-S, Trapncll BC, Crystal RG: In vivo antioxidanl gene expression in human airway epithelium of normal individuals exposed to 100% Oi, J Appl Physiol 1993;75:1256-1262.
4. Gillissen A: Oxidanticn und dcr protektive Ef-fekt von Glutathion, Atcmwcgs Lungenkr 1993;19:225-231.
5. Halliwell B, Cross CE: Oxygen-derived species: Their relation to human disease and environmental stress, Environ Health Perspect 1994: 102:5-12.
6. van Zandwijk N: N-acetvlcystcine for lung cancer prevention, Chest 1995;107:1437-1441.
7. Heffner JE, Repine JE: Pulmonary strategics of antioxidant defense, Am Rev Respir Dis 1989: 140:531-554.
8. Halliwell B, Gutteridge JMC: Free Radicals in Biology and Medicine, ed 2, Oxford, Clarendon Press, 1989.
9. Schraufstatter IU, Cochrane CG: Oxidants: Types, sources, and mechanisms of injury: in Crystal RG, West JB (eds): The lung, scientific foundations, New York, Raven Press, 1991, pp 1803-1810.
10. Sibille Y, Reynolds HY: Macrophages and polymorphonuclear neutrophils in lung defense and injury, Am Rev Respir Dis 1990:141:471-501.
11. Cluzel M, Damon M, Chanez P, Bousquet J, Crastes de Paulet A, Michel FB, Godard P: Enhanced alveolar cell luminol-dcpendent chemiluminescence in asthma, J Allergy Clin Immunol 1987;80:195-201.
12. Kalo M, Morikawa A, Kimura H, Shimizu T, Nakano M, Kuroume T: Effects of antiasthma drugs on superoxide anion generation from human polymorphonuclear leukocytes or the hy-poxanthine-xanthine oxidase system, Int Arch Allergy Appl Immunol 1991;96:128-133.
13. Mcltzer S, Goldberg B, Lad P, Easton J: Supcr-oxide generation and its modulation by adenosine in the neutrophils of subjects with asthma, J Allergy Clin Immunol 1984:83:960-966.
14. Ccrasoli JF, Tockcr J, Selig WM: Airway eosinophils from actively sensitized guinea pigs exhibit enhanced superoxide anion release in response to antigen challenge, Am J Respir Cell Mol Biol 1991:4:355-363.
15. Gillissen A, Birrcr P, Buhl R, Vogelmcier C, Hoyt RF, McElvaney NG, Hubbard RC, Crystal RG: Recombinant secretory leukoprotease inhibitor augments glutathione levels in respiratory epithelial lining fluid, J Appl Physiol 1993;75:825-832.
16. Gillissen A, Roum JH, Hoyt RF, Crystal RG: Augmentation of respiratory epithelial lining fluid antioxidant screen by aerosolizalion of recombinant human Cu*/Zn-’* superoxide dis-mutase, Chest 1993;104:811-815.
17. Buhl R, Borok Z, Vogelmcier C: Antioxidative Aerosol-Thcrapic mit Glutathion bei Patientcn mit idiopathischer Lungcnfibrose, Atemwegs Lungenkr 1993:19:235-241.
18. Borok Z, Buhl R, Grimes GJ, Bokscr AD, Hubbard RC, Holroyd KJ, Roum JH, Czcrski DB, Cantin AM, Crystal RG: Effect of glutathione aerosol on oxidant-antioxidant imbalance in idiopathic pulmonarv fibrosis, Lancet 1991: 338:215-216.
19. March J: Oxidation and reductions: in March J (ed): Advanced Organic Chemistry: Reactions, Mechanisms and Structure, New York, Wiley &Sons, 1985, pp 1048-1120.
20. Okada C, Sugivama H, Eda R, Miyagawa H, Hopp RJ, Bewtra AK, Townley RG: Effect of formotcrol on superoxidc anion generation from bronchoalvcolar lavage cells after antigen challenge in guinea pigs, Am J Respir Cell Mol Biol 1993;8:509-517.
21. Calhoun WJ, Stevens CA, Lambert SG: Modulation of superoxide production of alveolar macrophages and peripheral blood mononuclear cells by beta-agonists and theophylline, J Lab Clin Med 1991;117:514-522.
22. Gillissen A, Jaworska M, Scharling B, Schultze-Wcrninghaus G: Eine cinfachc Reinigungsmc-thode fur granulo- und monozytarc Zellen am Beispicl der Glutathionbestimmung in Serum und Zellen bei Patientcn mit einer COPD, Atemwegs Lungenkr 1994:20:308-309.
23. Crapo JD, McCord JM, Fridovich I: Preparation and assay of superoxide dismutase; in Fleischer S, Packer L (eds): Methods in Enzy-mology: Biomembranes, New York, Academic Press, 1978, vol 53, part D: Biological Oxidations, Mitochondrial and Microbial Svstems, pp 382-393.
24. Neijens HJ, Raatgeep RE, Degenhart HJ, Duivcrman EJ, Kcrrcbijn KF: Altered leukocyte response in relation to the basic abnormality in children with asthma and bronchial hyperresponsiveness, Am Rev Respir Dis 1984; 130:744-747.
25. Anderson WH, Cuss FM, Weiss EB: Calcium, calcium antagonists, and oxyradicals: in Weiss EB, Stein M (eds): Bronchial asthma: Mechanisms and therapeutics, New York, Little, Brown and Co, 1993, pp 945-971.
26. Calhoun WJ, Reed HE, Moesl DR, Stevens CA: Enhanced superoxidc production by alveolar macrophages and air-space cells, airway inflammation, and alveolar macrophages density changes after segmental antigen bronchoprovo-cation in allergic subjects, Am Rev Respir Dis 1992;145:317-325.
27. Jarjour NN, Bussc WW, Calhoun WJ: Enhanced production of oxygen radicals in nocturnal asthma, Am Rev Respir Dis 1992:146: 905-911.
28. Gillissen A, Scharling B, Schultze-Weming-haus G: The potency of fcnotcrol, tcrbutaline, isoproterenol and prednisolone to inhibit Oj and H1O2in vitro, Am J Respir Crit Care Med 1994:149:A805.
29. Buhl R, Vogelmcier C, Crittenden M, Hubbard RC, Hoyt RF Jr., Wilson EM, Cantin AM, Crystal RG: Augmentation of reduced glutathione levels in the epithelial lining fluid of the lower respiratory tract by direct aerosol administration of glutathione, Proc Natl Acad Sci USA 1990;87:4063-4067.
30. Llcwcllyn-Joncs CG, Stockley RA: The effects ofT-agonistsand methylxanthines on neutrophil function in vitro, Eur Respir J 1994;7: 1460-1466.
31. Hadjokas NE, Crowley JJ, Bayer CR, Nielson CP: i-Adrcnergic regulation of the eosinophil respiratory burst as delected by lucigenin-de-pendent luminescence, J Allergy Clin Immunol 1996;95:735-741.
32. Taniguchi K, Masuda Y, Takanaka K: Effects of be:a-adrencrgic agonists on metabolic activations of human neutrophils, J Pharmacobio-dyn 1991;14:435-442.
33. Mueller H, Motulsky HJ, Sklar LA: The potency and kinetics of the bcta-adrcncrgic receptors on human neutrophils, Mol Pharmacol 1988; 34:347-353.
34. Bussc WW: Decreased granulocyte response to isoproterenol in asthma during upper respiratory infections, Am Rev Respir Dis 1977:1 15: 783-791.
35. Webb DSA, Roth JA: Relationship of glucocorticoid suppression of arachidonic acid metabolism to alteration of neutrophil function, J Leukocyte Biol 1987;41:156-164.
36. Maridonneau-Parini I, Errasfa M, Russo-Ma-ric F: Inhibition of 07 generation by dexameth-asone is minified by lipocortin I in alveolar macrophages, J Clin Invest 1989:83:1936- 1940.
37. Driscoll K.E, Hassenbcin DG, Carter J, Poynter J, Asquith TN, Grant RA, Whitten J, Purdon MP, Takigiku R: Macrophage inflammatory proteins 1 and 2: Expression by rat alveolar macrophages, fibroblasts, and epithelial cells and in rat lung after mineral dust exposure, Am J Respir Cell Mol Biol 1993:8:311-318.
38. Alexander HR, Sheppard BC, Jensen JC, Lang-stein HN, Buresh CM, Venzon D, Walker EC, Fraker DL, Stovroff MC, Norton JA: Treatment with recombinant human tumor necrosis factor alpha protects rats against the lethality of hypotension and hypothermia of gram-negative sepsis, J Clin Invest 1991:88:34-39.
39. Harris ED: Regulation of antioxidant enzymes, FASEBJ 1992:6:2675-2683.