Synthesis of vinca alkaloids and related compounds LXXXIII. Unexpected Pictet-Spengler side-reaction

Tetrahedron Letters

Volumn 38, Issue 1, 1997, Pages 115-118

  Szabó, Lajos ^a   Szentirmay, Éva ^a   Baitz Qacs, Eszter ^b   Kalaus, György ^a   Szántay, Csaba ^a,b  

^a BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

^b CTRL RES INSTITUTE FOR CHEMISTRY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

VINCA ALKALOID;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0031013927     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(96)02230-7     Document Type: Article

References (8)

1. For part LXXXII see Moldvai, I.; Szántay Jr, Cs.; Szántay, Cs. Heterocycles, in press.
2. Saxton, J.E. in "Indoles"Part Four Ed. by J.E. Saxton. J. Wiley and Sons, New-York, 1983; pp. 439-465.
3. 3), 9.38(1H, s, CHO).
4. 2), 78.81 (9-C), 111.59(8́-C), 111.59(3́-C), 118.59(5́-C), 118.59(6́-C), 121.25(2́-C), 122.54(7́-C), 127.37(4́-C), 136.51(9́-C), 170.83(CO).
5. eq), 6.857.5(9H, m, aromatic), 9.75(2H, s, indole NH).
6. eq), 7.00-7.65(9H, m, aromatic), 10.59 and 11.62(2H, s, indole NH).
7. Kuehne, M.E. J. Amer. Chem. Soc. 1994 , 86 , 2946.
8. Cox, E.D. and Cook, J.M. Chem. Rev. 1995, 1797, and citations therein.