Synergistic antinociceptive interactions of morphine and clonidine in rats with nerve-ligation injury

Anesthesiology

Volumn 86, Issue 1, 1997, Pages 196-204

  Ossipov, Michael H ^b   Lopez, Yvan ^b   Bian, Di ^b   Nichols, Michael L ^b   Porreca, Frank ^a  

^a UNIVERSITY OF ARIZONA   (United States)

^b NONE

Author keywords

morphine clonidine synergy, neuropathic pain, antinociception, rat,intrathecal

Indexed keywords

BUPIVACAINE; CLONIDINE; DIZOCILPINE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; MORPHINE; NALOXONE; PHENTOLAMINE;

ALLODYNIA; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG POTENTIATION; ETIOLOGY; HYPERALGESIA; INTRAPERITONEAL DRUG ADMINISTRATION; INTRATHECAL DRUG ADMINISTRATION; MALE; MECHANICAL STIMULATION; NERVE LIGATION; NONHUMAN; PRIORITY JOURNAL; RAT; TAIL FLICK TEST; THERMAL STIMULATION;

ADRENERGIC ALPHA-AGONISTS; ANALGESICS; ANIMALS; CLONIDINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; ENKEPHALINS; INJECTIONS, INTRAPERITONEAL; INJECTIONS, SPINAL; MALE; MORPHINE; PAIN; PHENTOLAMINE; RATS; RATS, SPRAGUE-DAWLEY; SPINAL NERVE ROOTS;

EID: 0031013659     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199701000-00024     Document Type: Article

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