Combinational epitope search: Pitfalls of library design

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 1, 1997, Pages 95-98

  Yu, Zhiguang ^a   Chu, Yen Ho ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; FLAGELLIN; SYNTHETIC PEPTIDE;

ANTIGEN BINDING; ARTICLE; BORRELIA BURGDORFERI; DRUG DESIGN; ENZYME LINKED IMMUNOSORBENT ASSAY; IN VITRO STUDY; LIGAND BINDING; STRUCTURE ACTIVITY RELATION;

EID: 0031013298     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(96)00585-9     Document Type: Article

References (9)

1. Schneider, T.; Lange, R.; Ronspeck, W.; Weigelt, W.; Kolmel, H. W. Infec. Immun. 1992, 60, 316.
2. Fikrig, E.; Berland, R.; Chen, M.; Williams, S.; Sigal, L. H.; Flavell, R. A. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 1830.
3. Youngquist, R. S.; Fuentes, G. R.; Lacey, M. P.; Keough, T. J. Am. Chem. Soc. 1995, 117, 3900.
4. Our discovery of the new consensus sequence from combinatorial epitope library will be reported elsewhere.
5. Parks, M. E.; Baird, E. E.; Dervan P. B. J. Am. Chem. Soc. 1996, 118, 6147.
6. Yu, Z.; Carter, J. M.; Huang, S. Y.; Lackland, H.; Sigal, L. H.; Stein, S. Bioconjugate Chem. 1996, 7, 338.
7. Lam, K. S.; Salmon, S. E.; Hersh, E. M.; Hruby, V. J.; Kazmierski, W. M.; Knapp, R. J. Nature (London) 1991, 354, 82.
8. Houghten, R. A.; Pinilla, C.; Blondelle, S. E.; Appel, J. R.; Dooley, C. T.; Cuervo, J. H. Nature (London) 1991, 354, 84.
9. Chu, Y.-H.; Avila, L. Z.; Gao, J.; Whitesides, G. M. Acc. Chem. Res. 1995, 28, 461.