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Volumn 29, Issue 1, 1997, Pages 69-74

In swine myocardium, the infarct size reduction induced by U-89232 is glibenclamide sensitive: Evidence that U-89232 is a cardioselective opener of ATP-sensitive potassium channels

Author keywords

Cardioselective K(ATP) channel opener; Glibenclamide; Infarct size; U 89232

Indexed keywords

APRIKALIM; BIMAKALIM; CROMAKALIM; GLIBENCLAMIDE; N (4 CHLOROPHENYL) N' CYANO N'' (6 CYANO 3,4 DIHYDRO 3 HYDROXY 2,2 DIMETHYL 2H 1 BENZOPYRAN 4 YL)GUANIDINE; NICORANDIL; PINACIDIL; POTASSIUM CHANNEL; POTASSIUM CHANNEL STIMULATING AGENT; U 89232; UNCLASSIFIED DRUG;

EID: 0031012791     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199701000-00011     Document Type: Article
Times cited : (5)

References (35)
  • 1
    • 0026648690 scopus 로고
    • Nicorandil attenuates myocardial dysfunction associated with transient ischemia by opening ATP-sensitive potassium channels
    • Auchampach JA, Cavero I, Gross GJ. Nicorandil attenuates myocardial dysfunction associated with transient ischemia by opening ATP-sensitive potassium channels. J Cardiovasc Pharmacol 1992; 20:765-71.
    • (1992) J Cardiovasc Pharmacol , vol.20 , pp. 765-771
    • Auchampach, J.A.1    Cavero, I.2    Gross, G.J.3
  • 2
    • 0024534172 scopus 로고
    • Cromakalim, nicorandil and pinacidil: Novel drugs which open potassium channels in smooth muscle
    • Hamilton TC, Weston AH. Cromakalim, nicorandil and pinacidil: novel drugs which open potassium channels in smooth muscle. Gen Pharmacol 1989;20:1-9.
    • (1989) Gen Pharmacol , vol.20 , pp. 1-9
    • Hamilton, T.C.1    Weston, A.H.2
  • 3
    • 0025696538 scopus 로고
    • Pharmacological profile of cromakalim in the treatment of myocardial ischemia in isolated rat hearts and anesthetized dogs
    • Grover GJ, Sleph PG, Dzwonezvk S. Pharmacological profile of cromakalim in the treatment of myocardial ischemia in isolated rat hearts and anesthetized dogs. J Cardiovasc Pharmacol 1990;16: 853-64.
    • (1990) J Cardiovasc Pharmacol , vol.16 , pp. 853-864
    • Grover, G.J.1    Sleph, P.G.2    Dzwonezvk, S.3
  • 4
    • 0026346285 scopus 로고
    • + channel opener RP 52891 reduces experimental infarct size in dogs in absence of systemic hemodynamic changes
    • + channel opener RP 52891 reduces experimental infarct size in dogs in absence of systemic hemodynamic changes. J Pharmacol Exp Ther 1991;259:961-7.
    • (1991) J Pharmacol Exp Ther , vol.259 , pp. 961-967
    • Auchampach, J.A.1    Matuyama, M.2    Cavero, I.3    Gross, G.J.4
  • 7
    • 0026707772 scopus 로고
    • Therapeutic potential of modulating potassium currents in diseased myocardium
    • Lynch JJ, Sanguinetti MC, Kimura S, Basset AL. Therapeutic potential of modulating potassium currents in diseased myocardium. FASEB J 1992;6:2952-60.
    • (1992) FASEB J , vol.6 , pp. 2952-2960
    • Lynch, J.J.1    Sanguinetti, M.C.2    Kimura, S.3    Basset, A.L.4
  • 8
    • 0025358820 scopus 로고
    • The protective effects of cromakalim and pinacidil on reperfusion function and infarct size in isolated perfused rat hearts and anesthetized dogs
    • Grover GJ, Dzwonczyk S, Parham CS, Sleph PG. The protective effects of cromakalim and pinacidil on reperfusion function and infarct size in isolated perfused rat hearts and anesthetized dogs. Cardiovasc Drugs Ther 1990;4:465-74.
    • (1990) Cardiovasc Drugs Ther , vol.4 , pp. 465-474
    • Grover, G.J.1    Dzwonczyk, S.2    Parham, C.S.3    Sleph, P.G.4
  • 9
    • 0025085921 scopus 로고
    • Reduction of ischemic damage in isolated rat hearts by the potassium channel opener RP 52891
    • Grover GJ, Dzwonezvk S, Sleph PG. Reduction of ischemic damage in isolated rat hearts by the potassium channel opener RP 52891. Eur J Pharmacol 1990;191:11-9.
    • (1990) Eur J Pharmacol , vol.191 , pp. 11-19
    • Grover, G.J.1    Dzwonezvk, S.2    Sleph, P.G.3
  • 10
    • 0025611417 scopus 로고
    • + channel current in atrial myocytes of guinea pig heart
    • + channel current in atrial myocytes of guinea pig heart. Jpn J Pharmacol 1990;54:473-7.
    • (1990) Jpn J Pharmacol , vol.54 , pp. 473-477
    • Hamada, F.1    Takikawa, R.2    Ito, H.3
  • 11
    • 0026547286 scopus 로고
    • Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs
    • Gross GJ, Auchampach JA. Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs. Circ Res 1992;70:223-33.
    • (1992) Circ Res , vol.70 , pp. 223-233
    • Gross, G.J.1    Auchampach, J.A.2
  • 14
    • 85047679591 scopus 로고
    • Protective effects of ATP sensitive potassium channel openers in models of myocardial ischaemia
    • Grover GJ. Protective effects of ATP sensitive potassium channel openers in models of myocardial ischaemia. Cardiovasc Res 1994; 28:778-82.
    • (1994) Cardiovasc Res , vol.28 , pp. 778-782
    • Grover, G.J.1
  • 15
    • 0028182423 scopus 로고
    • ATP-channel opener bimakalim on coronary blood flow, monophasic action potential duration, and infarct size in dogs
    • ATP-channel opener bimakalim on coronary blood flow, monophasic action potential duration, and infarct size in dogs. Circulation 1994;89:1769-75.
    • (1994) Circulation , vol.89 , pp. 1769-1775
    • Yao, Z.1    Gross, G.J.2
  • 16
    • 0029067010 scopus 로고
    • U-89232 (BMS-189365), a novel antiischemic agent derived from cromakalim
    • Toombs CF, Shebuski RJ. U-89232 (BMS-189365), a novel antiischemic agent derived from cromakalim. Cardiovasc Drug Rev 1995;12:303-16.
    • (1995) Cardiovasc Drug Rev , vol.12 , pp. 303-316
    • Toombs, C.F.1    Shebuski, R.J.2
  • 18
    • 0029081730 scopus 로고
    • Activation of ATP-sensitive potassium channels: A novel pharmacological approach to myocardial protection?
    • Hearse DJ. Activation of ATP-sensitive potassium channels: a novel pharmacological approach to myocardial protection? Cardiovasc Res 1995;30:1-17.
    • (1995) Cardiovasc Res , vol.30 , pp. 1-17
    • Hearse, D.J.1
  • 19
    • 0028804154 scopus 로고
    • Glyburide-reversible cardioprotective effect of BMS-180448 is independent of action potential shortening
    • Grover GJ, D'Alonzo AJ, Hess T, Sleph PG, Darbenzio RB. Glyburide-reversible cardioprotective effect of BMS-180448 is independent of action potential shortening. Cardiovasc Res 1995;30: 731-8.
    • (1995) Cardiovasc Res , vol.30 , pp. 731-738
    • Grover, G.J.1    D'Alonzo, A.J.2    Hess, T.3    Sleph, P.G.4    Darbenzio, R.B.5
  • 20
    • 0028335417 scopus 로고
    • Cardioprotection with U-89232 is not reversible with glibenclamide: Evidence of a novel anti-ischemic agent derived from cromakalim
    • Toombs CF, Moore TL, Shebuski RJ. Cardioprotection with U-89232 is not reversible with glibenclamide: evidence of a novel anti-ischemic agent derived from cromakalim. Pharmacology 1994;49:96-104.
    • (1994) Pharmacology , vol.49 , pp. 96-104
    • Toombs, C.F.1    Moore, T.L.2    Shebuski, R.J.3
  • 21
    • 0028332197 scopus 로고
    • Effect of bimakalim (EMD 52692), an opener of ATP-sensitive potassium channels, on infarct size, coronary blood flow, regional wall function, and oxygen consumption in swine
    • Rohmann S, Weygandt H, Schelling P, et al. Effect of bimakalim (EMD 52692), an opener of ATP-sensitive potassium channels, on infarct size, coronary blood flow, regional wall function, and oxygen consumption in swine. Cardiovasc Res 1994;28:858-63.
    • (1994) Cardiovasc Res , vol.28 , pp. 858-863
    • Rohmann, S.1    Weygandt, H.2    Schelling, P.3
  • 22
    • 0028302316 scopus 로고
    • Comparative effects of the potassium channel openers cromakalim and pinacidil and the cromakalim analog U-89232 on isolated vascular and cardiac tissue
    • Norman NR, Toombs CF, Khan SA, et al. Comparative effects of the potassium channel openers cromakalim and pinacidil and the cromakalim analog U-89232 on isolated vascular and cardiac tissue. Pharmacology 1994;49:86-95.
    • (1994) Pharmacology , vol.49 , pp. 86-95
    • Norman, N.R.1    Toombs, C.F.2    Khan, S.A.3
  • 23
    • 0026969018 scopus 로고
    • Limitation of myocardial injury with the potassium channel opener cromakalim and the nonvasoactive analog U-89,232: Vascular vs. cardiac actions in vitro and in vivo
    • Toombs CF, Norman NR, Groppi VE, Lee KS, Gadwood RC, Shebuski RJ. Limitation of myocardial injury with the potassium channel opener cromakalim and the nonvasoactive analog U-89,232: vascular vs. cardiac actions in vitro and in vivo. J Pharmacol Exp Ther 1992;263:1261-8.
    • (1992) J Pharmacol Exp Ther , vol.263 , pp. 1261-1268
    • Toombs, C.F.1    Norman, N.R.2    Groppi, V.E.3    Lee, K.S.4    Gadwood, R.C.5    Shebuski, R.J.6
  • 26
    • 0026490398 scopus 로고
    • Ischemic preconditioning protects against infarction in rat hearts
    • Liu Y, Downey JM. Ischemic preconditioning protects against infarction in rat hearts. Am J Physiol 1992;263:H1107-12.
    • (1992) Am J Physiol , vol.263
    • Liu, Y.1    Downey, J.M.2
  • 27
    • 0343150202 scopus 로고
    • ATP-sensitive potassium channel activation does not mediate preconditioning in isolated rat hearts
    • Grover GJ, Dzwonczyk S, Sleph PG. ATP-sensitive potassium channel activation does not mediate preconditioning in isolated rat hearts [Abstract]. Circulation 1992;86(suppl I):I-341.
    • (1992) Circulation , vol.86 , Issue.1 SUPPL.
    • Grover, G.J.1    Dzwonczyk, S.2    Sleph, P.G.3
  • 28
    • 0027240733 scopus 로고
    • Blockade of ATP-sensitive potassium channels increases infarct size but does not prevent preconditioning in rabbit hearts
    • Thornton J, Thornton CS, Sterling DL, Downey JM. Blockade of ATP-sensitive potassium channels increases infarct size but does not prevent preconditioning in rabbit hearts. Circ Res 1993;72: 44-9.
    • (1993) Circ Res , vol.72 , pp. 44-49
    • Thornton, J.1    Thornton, C.S.2    Sterling, D.L.3    Downey, J.M.4
  • 29
    • 0027493751 scopus 로고
    • An explanation for the reported observation that ATP dependant potassium channel openers mimic preconditioning
    • Downey JM. An explanation for the reported observation that ATP dependant potassium channel openers mimic preconditioning. Cardiovasc Res 1993;27:1565.
    • (1993) Cardiovasc Res , vol.27 , pp. 1565
    • Downey, J.M.1
  • 30
    • 0000197349 scopus 로고
    • Role of ATP-sensitive potassium channels in ischemic preconditioning
    • Przyklenk K, Kloner RA, Yellon DM, eds. Boston: Kluwer Academic Publishers
    • Gross GJ, Yao Z, Auchampach JA. Role of ATP-sensitive potassium channels in ischemic preconditioning. in: Przyklenk K, Kloner RA, Yellon DM, eds. Ischemic preconditioning: the concept of endogenous cardioprotection. Boston: Kluwer Academic Publishers, 1994:125-35.
    • (1994) Ischemic Preconditioning: the Concept of Endogenous Cardioprotection , pp. 125-135
    • Gross, G.J.1    Yao, Z.2    Auchampach, J.A.3
  • 31
    • 0027285011 scopus 로고
    • Limitation of infarct size in the rabbit by ischemic preconditioning is reversible with glibenclamide
    • Toombs CF, Moore TL, Shebuski RJ. Limitation of infarct size in the rabbit by ischemic preconditioning is reversible with glibenclamide. Cardiovasc Res 1993;27:617-22.
    • (1993) Cardiovasc Res , vol.27 , pp. 617-622
    • Toombs, C.F.1    Moore, T.L.2    Shebuski, R.J.3
  • 32
    • 0028332204 scopus 로고
    • Cardiovascular controversies: Potassium channel openers are likely to be proarrhythmic in the diseased human heart
    • Black CS, Lucchesi BR. Cardiovascular controversies: potassium channel openers are likely to be proarrhythmic in the diseased human heart. Cardiovasc Res 1994;28:923-4.
    • (1994) Cardiovasc Res , vol.28 , pp. 923-924
    • Black, C.S.1    Lucchesi, B.R.2
  • 33
    • 0026635995 scopus 로고
    • Modulation of potassium channels by antiarrhythmic and antihypertensive drugs
    • Sanguinetti MC. Modulation of potassium channels by antiarrhythmic and antihypertensive drugs. Hypertension 1992;19:228-36.
    • (1992) Hypertension , vol.19 , pp. 228-236
    • Sanguinetti, M.C.1
  • 34
    • 85047680900 scopus 로고
    • Electrophysiological effects of ATP sensitive potassium channel modulation: Implications for arrhythmogenesis
    • Wilde AAM, Janse MJ. Electrophysiological effects of ATP sensitive potassium channel modulation: implications for arrhythmogenesis. Cardiovasc Res 1994;28:16-24.
    • (1994) Cardiovasc Res , vol.28 , pp. 16-24
    • Wilde, A.A.M.1    Janse, M.J.2
  • 35
    • 0027767613 scopus 로고
    • Potassium channel blockade and acute myocardial infarction: Implications for management of the non-insulin requiring diabetic patient
    • Hofman D, Opie LH. Potassium channel blockade and acute myocardial infarction: implications for management of the non-insulin requiring diabetic patient. Eur Heart J 1993;14:1585-9.
    • (1993) Eur Heart J , vol.14 , pp. 1585-1589
    • Hofman, D.1    Opie, L.H.2


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