Thermal effects of neutralization therapy and water dilution for acute alkali exposure in canines

Academic Emergency Medicine

Volumn 4, Issue 1, 1997, Pages 27-32

  Homan, Clark S ^a   Singer, Adam J ^a   Henry, Mark C ^a   Thode Jr , Henry C ^a  

^a STONY BROOK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

alkali; animal study; burn; neutralization; stomach; toxicology

Indexed keywords

ALKALI; WATER;

ALKALINITY; ANIMAL EXPERIMENT; ARTICLE; BURN; DOG; NONHUMAN; PRIORITY JOURNAL; STOMACH ABSORPTION; TEMPERATURE MEASUREMENT; THERMAL ANALYSIS; TISSUE INJURY;

EID: 0031012734     PISSN: 10696563     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1553-2712.1997.tb03639.x     Document Type: Article

References (39)

1. Howell JM. Alkaline ingestions. Ann Emaciate Med. 1986; 15: 820-5.
2. Homan CS. Acid and alkali toxicity. In: Viccellio P (ed). Handbook of Toxicology, ed. 1. Boston: Little, Brown, 1992, p 249-63.
3. Maull KI, Osmand AP, Maull CD. Liquid caustic ingestions: an in vitro study of the effect of buffer, neutralization and dilution. Ann Emerg Med. 1985; 14:1160-2.
4. Homan CS, Maitra SR, Lane BP, Thode HC Jr, Finkelshteyn J, Davidson L. Effective treatment for acute alkali injury to the esophagus using weak-acid neutralization therapy: an ex-vivo study. Acad Emerg Med. 1995; 2:952-8.
5. Knopp R. Caustic ingestions. J Am Coll Emerg Physicians. 1979; 8: 329-36.
6. Rumack BH. Poisindex Information System. Denver Micromedex 1994, Vol. 79.
7. Ellenhom MJ, Barceloux DG. Household products. In: Ellenhom MJ, Barceloux DG (eds). Medical Toxicology Diagnosis and Treatment of Human Poisoning, ed 1. New York: Elsevier Science, 1988, pp 930-3.
8. Moore WR. Caustic ingestions. Clin Pediatr. 1986; 25:192-6.
9. Gumaste VV, Dave PB. Ingestion of corrosive substances by adults. Am J Gastroenterol. 1992; 87:1-5.
10. Rumack BH, Burrington JD. Caustic ingestions: a rational look at diluents. Clin Toxicol. 1977; 11:27-34.
11. Litovitz TL, Felberg L, Soloway RA, Ford M, Geller R. 1994 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med. 1995; 13: 551-97.
12. Homan CS, Maitra SR, Lane BP, Thode HC Jr, Sable M. Therapeutic effects of water and milk for acute alkali injury of the esophagus. Ann Emerg Med. 1994; 24:14-20.
13. Middelkamp JN, Cone AJ, Ogura JH, et al. Endoscopic diagnosis and steroid and antibiotic therapy of acute lye burns of the esophagus. Laryngoscope. 1969; 58:685-93.
14. Anderson KD, Rouse TM, Randolph JG. A controlled trial of corticosteroids in children with corrosive injury of the esophagus. N Engl J Med. 1990; 323:637-40.
15. Haller JA, Bachman BA. The comparative effect of current therapy on experimental caustic burns of the esophagus. Pediatrics. 1964; 34: 236-45.
16. Ehrenpreis ED, Leiken JB. Use of oral sodium polyacrylate in rat gastrointestinal burns. Vet Hum Toxicol. 1988; 30:135-8.
17. Liu AJ, Richardson MA. Effects of N-acetylcysteine on experimentally induced lye injury. Ann Otol Laryngol. 1985; 94:477-82.
18. 2 inhalation. Am J Physiol. 1993; 264: G150-G156.
19. Dilawari JB, Singh S, Rao PN, Anand BS. Corrosive acid ingestion in man - a clinical and endoscopic study. Gut. 1984; 25:183-7.
20. Sugawa C, Mullins RJ, Lucas CE, Leibold WC. The value of early endoscopy following caustic ingestion. Surg Gynecol Obstet. 1981; 153: 553-6.
21. Wijburg FA, Beukers MM, Heymans HS, Bartelsman JF, Hartog Jager FC. Nasogastric intubation as sole treatment of caustic esophageal lesions. Ann Otol Laryngol. 1985; 94:337-41.
22. Mills LJ, Estrera AS, Platt MR. Avoidance of esophageal stricture following severe caustic burns by the use of an intraluminal stent. Ann Thorac Surg. 1979; 28:60-5.
23. Hogan RB, Polter DE. Nonsurgical management of lye-induced antral stricture with hydrostatic balloon dilation. Gastrointest Endosc. 1986; 32:228-30.
24. Knox WG, Scott JR, Zintel HA, Guthrie R, McCabe RE. Bouginage and steroids used singly or in combination in experimental corrosive esophagitis. Ann Surg. 1967; 166:930-41.
25. Gago O, Ritter FN, Martel W, et al. Aggressive surgical treatment for caustic injury of the esophagus and stomach. Ann Thorac Surg. 1972; 13:243-50.
26. Wu M, Lai W. Surgical management of extensive corrosive injuries of the alimentary tract. Surg Gynecol Obstet. 1993; 177:12-6.
27. Estrera A, Taylor W, Mills LJ, et al. Corrosive burns of the esophagus and stomach: a recommendation for an aggressive surgical approach. Ann Thorac Surg. 1986; 41:276-83.
28. Rubin MM, Jui V, Cozzi G. Treatment of caustic ingestion. J Oral Maxillofac Surg. 1989; 47:286-90.
29. Espinola TE, Amedee RG. Caustic ingestion and esophageal injury. J La State Med Soc. 1993; 145:121-5.
30. Homan CS, Maitra SR, Lane BP, et al. Effective treatment of acute alkali injury of the rat esophagus with early saline dilution therapy. Ann Emerg Med. 1993; 22:178-82.
31. Homan CS, Maitra SR, Lane BP, Thode HC Jr, Davidson L. Histopathologic evaluation of the therapeutic efficacy of water and milk dilution for esophageal acid injury. Acad Emerg Med. 1995; 2:587-91.
32. Ashcraft KW, Padula RT. The effect of dilute corrosives on the esophagus. Pediatrics. 1974; 53:226-32.
33. Fisher RA, Eckhauser ML, Radivoyevitch M. Acid ingestion in an experimental model. Surg Gynecol Obstet. 1985; 161:91-9.
34. Leape L, Ashcraft KW, Scarpelli D. Hazard to health - liquid lye N Engl J Med. 1971; 284:578-82.
35. Krey H. On treatment of corrosive lesions of the esophagus: experimental study. Acta Otolaryngol Suppl (Stockh). 1952; 102:1-49.
36. Allen RE, Thoshinsky MJ, Stallone RJ, et al. Corrosive injuries of the stomach. Arch Surg. 1970; 100:409-13.
37. Zargar SA, Kochhar R, Mehta S, Mehta SK. The role of fiberoptic endoscopy in the management of corrosive ingestion and modified endoscopic classification of burns. Gastrointest Endosc. 1991; 37:165-9.
38. Gill RA, Pertel PR, Merrit VE. Encapsulated alkali ingestion has a characteristic appearance. Gastrointest Endosc. 1986; 32:121-2.
39. Johns TT, Theoni RF. Severe corrosive gastritis related to Drano: an unusual case. Gastrointest Radiol. 1983; 8:25-8.