First syntheses of (2S,3S)- and (2S,3R) - m-prenyl-β-hydroxytyrosine derivatives: Bioactive amino acid fragment of a substance P antagonist novel cyclic heptapeptide

Tetrahedron Letters

Volumn 38, Issue 3, 1997, Pages 473-476

  Kumar, Jalluri S Ravi ^a   Datta, Apurba ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; SUBSTANCE P ANTAGONIST; TYROSINE DERIVATIVE;

ARTICLE; CHIRALITY; DRUG SYNTHESIS; IN VITRO STUDY; METHODOLOGY; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0031012722     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(96)02298-8     Document Type: Article

References (9)

1. IICT Communication No. 3740
2. (a) Barrow, C. J.; Doleman, M. S.; Bobko, M. A.; Cooper, R. J. Med. Chem. 1994, 37, 356-363.
3. (b) Barrow, C. J.; Sedlock, D. M.; Sun, H. H.; Cooper, R.; Gillum, A. M. J. Antibiot. 1994, 47, 1182-1187.
4. Hurd, C. D.; Hoffman, W. A. J. Org. Chem. 1940, 5, 212 - 222.
5. (a) Garner, P.; Park, J. M. J. Org. Chem. 1987, 52, 2361-2364.
6. (b) McKillop, A.; Taylor, R. J. K.; Watson, R. J.; Lewis, N. Synthesis, 1994, 31-33.
7. Williams, L.; Zhang, Z.; Shao, F.; Carrall, P. J.; Joullié, M. M. Tetrahedron, 1996, 52, 11673-11694.
8. . Doi, Y.; Ishibashi, M.; Kobayashi, J. Tetrahedron, 1996, 52, 4573-4580.
9. 3) δ 157.1, 130.0, 127.2, 124.5, 122.3, 110.1, 77.2, 77.2, 62.2, 55.4, 31.9, 30.0, 29.7, 29.3, 28.6, 28.2, 25.8, 17.8 ; MS (FAB+) 380 (MH+).