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Volumn 68, Issue 2, 1997, Pages 732-738

Neuroprotective effect of the iron chelator desferrioxamine against MPP+ toxicity on striatal dopaminergic terminals

Author keywords

1 Methyl 4 phenylpyridinium; Dopamine; Iron chelator; Microdialysis; Rat; Striatum

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; CHELATING AGENT; DEFEROXAMINE; DOPAMINE; FERRIC CHLORIDE;

EID: 0031012716     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.68020732.x     Document Type: Article
Times cited : (33)

References (48)
  • 1
    • 0026087383 scopus 로고
    • Oxygen free radicals and Parkinson's disease
    • Adams J. D. and Odunze I. N. (1991) Oxygen free radicals and Parkinson's disease. Free Radic. Biol. Med. 10, 161-169.
    • (1991) Free Radic. Biol. Med. , vol.10 , pp. 161-169
    • Adams, J.D.1    Odunze, I.N.2
  • 4
    • 0025122203 scopus 로고
    • Induction by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine of lipid peroxidation in vivo in vitamin E deficient mice
    • Adams J. D., Odunze I. N., and Sevenian A. (1990) Induction by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine of lipid peroxidation in vivo in vitamin E deficient mice. Biochem. Pharmacol. 39, R5-R8.
    • (1990) Biochem. Pharmacol. , vol.39
    • Adams, J.D.1    Odunze, I.N.2    Sevenian, A.3
  • 6
    • 0029009518 scopus 로고
    • Involvement of free-radicals in MPP neurotoxicity against rat dopaminergic-neurons in culture
    • Akenaya Y., Takahashi M., and Hatanaka H. (1995) Involvement of free-radicals in MPP neurotoxicity against rat dopaminergic-neurons in culture. Neurosci. Lett. 193, 53-56.
    • (1995) Neurosci. Lett. , vol.193 , pp. 53-56
    • Akenaya, Y.1    Takahashi, M.2    Hatanaka, H.3
  • 7
    • 0029988893 scopus 로고    scopus 로고
    • + toxicity in rat striatal slices - Relationship between nonselective effects and free-radical production
    • + toxicity in rat striatal slices - relationship between nonselective effects and free-radical production. Neurochem. Res. 21, 73-78.
    • (1996) Neurochem. Res. , vol.21 , pp. 73-78
    • Ambrosio, S.1    Espino, A.2    Cutillas, B.3    Bartrons, R.4
  • 8
    • 0026040282 scopus 로고
    • Iron-melanin interaction and lipid peroxidation: Implication for Parkinson's disease
    • Ben-Shachar D., Riederer P., and Youdim M. B. H. (1991) Iron-melanin interaction and lipid peroxidation: implication for Parkinson's disease. J. Neurochem. 57, 1609-1614.
    • (1991) J. Neurochem. , vol.57 , pp. 1609-1614
    • Ben-Shachar, D.1    Riederer, P.2    Youdim, M.B.H.3
  • 9
    • 0015882341 scopus 로고
    • The mitochondrial generation of hydrogen peroxide
    • Boveris A. and Chance B. (1973) The mitochondrial generation of hydrogen peroxide. Biochem. J. 134, 707-716.
    • (1973) Biochem. J. , vol.134 , pp. 707-716
    • Boveris, A.1    Chance, B.2
  • 10
    • 0023220996 scopus 로고
    • Chemically induced Parkinson's disease: Intermediates in the oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine to the 1-methyl-4-phenylpyridinium ion
    • Chacon J. N., Chedekel M. R., Land E. J., and Truscott T. G. (1987) Chemically induced Parkinson's disease: intermediates in the oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine to the 1-methyl-4-phenylpyridinium ion. Biochem. Biophys. Res. Commun. 144, 957-964.
    • (1987) Biochem. Biophys. Res. Commun. , vol.144 , pp. 957-964
    • Chacon, J.N.1    Chedekel, M.R.2    Land, E.J.3    Truscott, T.G.4
  • 11
    • 0021276089 scopus 로고
    • Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase
    • Chiba K., Trevor A., and Castagnoli N. Jr. (1984) Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase. Biochem. Biophys. Res. Commun. 120, 574-578.
    • (1984) Biochem. Biophys. Res. Commun. , vol.120 , pp. 574-578
    • Chiba, K.1    Trevor, A.2    Castagnoli Jr., N.3
  • 12
    • 0021339035 scopus 로고
    • Neurochemical and behavioral effects of systemic and intranigral administration of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the rat
    • Chiueh C. C., Markey S. P., Burns R. S., Johannessen J. N., Pert A., and Kopin I. J. (1984) Neurochemical and behavioral effects of systemic and intranigral administration of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the rat. Eur. J. Pharmacol. 100, 189-194.
    • (1984) Eur. J. Pharmacol. , vol.100 , pp. 189-194
    • Chiueh, C.C.1    Markey, S.P.2    Burns, R.S.3    Johannessen, J.N.4    Pert, A.5    Kopin, I.J.6
  • 13
    • 0026683140 scopus 로고
    • Enhanced hydroxyl radical generation by 2′-methyl analogue of MPTP: Suppression by clorgyline and deprenyl
    • Chiueh C. C., Huang S. J., and Murphy D. L. (1992) Enhanced hydroxyl radical generation by 2′-methyl analogue of MPTP: suppression by clorgyline and deprenyl. Synapse 11, 346-348.
    • (1992) Synapse , vol.11 , pp. 346-348
    • Chiueh, C.C.1    Huang, S.J.2    Murphy, D.L.3
  • 14
    • 0026598930 scopus 로고
    • Irreversible inhibition of mitochodrial complex I by 1-methyl-4-phenylpyridinium: Evidence for free radical involvement
    • Cleeter M. W. J., Cooper J. M., and Shapira A. H. V. (1992) Irreversible inhibition of mitochodrial complex I by 1-methyl-4-phenylpyridinium: evidence for free radical involvement. J. Neurochem. 58, 786-789.
    • (1992) J. Neurochem. , vol.58 , pp. 786-789
    • Cleeter, M.W.J.1    Cooper, J.M.2    Shapira, A.H.V.3
  • 15
    • 0022349344 scopus 로고
    • 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in mice is enhanced by pretreatment with diethyldithiocarbamate
    • Corsini G., Pintus S., Chiueh C. C., Weiss J. F., and Kopin I. (1985) 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in mice is enhanced by pretreatment with diethyldithiocarbamate. Eur. J. Pharmacol. 119, 127-128.
    • (1985) Eur. J. Pharmacol. , vol.119 , pp. 127-128
    • Corsini, G.1    Pintus, S.2    Chiueh, C.C.3    Weiss, J.F.4    Kopin, I.5
  • 18
    • 0002936617 scopus 로고
    • Chemical and physical properties of superoxide
    • (Michelson A. M., McCord J. M., and Fridovich I., eds), Academic Press, New York
    • Fee J. A. and Valentine J. S. (1977) Chemical and physical properties of superoxide, in Superoxide and Superoxide Dismutase (Michelson A. M., McCord J. M., and Fridovich I., eds), pp. 19-60. Academic Press, New York.
    • (1977) Superoxide and Superoxide Dismutase , pp. 19-60
    • Fee, J.A.1    Valentine, J.S.2
  • 20
    • 0028000825 scopus 로고
    • Altered brain metabolism of iron as a cause of neurodegenerative disease?
    • Gerlach M., Ben-Shachar D., Riederer P., and Youdim M. B. H. (1994) Altered brain metabolism of iron as a cause of neurodegenerative disease? J. Neurochem. 63, 793-807.
    • (1994) J. Neurochem. , vol.63 , pp. 793-807
    • Gerlach, M.1    Ben-Shachar, D.2    Riederer, P.3    Youdim, M.B.H.4
  • 21
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • Halliwell B. (1992) Reactive oxygen species and the central nervous system. J. Neurochem. 59, 1609-1623.
    • (1992) J. Neurochem. , vol.59 , pp. 1609-1623
    • Halliwell, B.1
  • 22
    • 0024997609 scopus 로고
    • +) induces NADH dependent superoxide formation, and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles
    • +) induces NADH dependent superoxide formation, and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles. Biochem. Biophys. Res. Commun. 170, 1049-1055.
    • (1990) Biochem. Biophys. Res. Commun. , vol.170 , pp. 1049-1055
    • Hasegawa, E.1    Takeshige, K.2    Oishi, T.3    Murai, Y.4    Minikami, S.5
  • 23
    • 0021280826 scopus 로고
    • Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice
    • Heikkila R. E., Hess A., and Duvoisin R. C. (1984) Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Science 224, 1451-1453.
    • (1984) Science , vol.224 , pp. 1451-1453
    • Heikkila, R.E.1    Hess, A.2    Duvoisin, R.C.3
  • 26
    • 0021337873 scopus 로고
    • Selective nigral toxicity after systemic administration of 1-methyl-4-pheny-1,2,3,6-tetrahydropyridine (MPTP) in the squirrel monkey
    • Langston J. W., Forno L. S., Rebert C. S., and Irwin I. (1984) Selective nigral toxicity after systemic administration of 1-methyl-4-pheny]-1,2,3,6-tetrahydropyridine (MPTP) in the squirrel monkey. Brain Res. 292, 390-394.
    • (1984) Brain Res. , vol.292 , pp. 390-394
    • Langston, J.W.1    Forno, L.S.2    Rebert, C.S.3    Irwin, I.4
  • 27
    • 0024413893 scopus 로고
    • + on the release of serotonin and 5-hydroxyindoleacetie acid from rat striatum in vivo
    • + on the release of serotonin and 5-hydroxyindoleacetie acid from rat striatum in vivo. Eur. J. Pharmacol. 166, 49-55.
    • (1989) Eur. J. Pharmacol. , vol.166 , pp. 49-55
    • Miyake, H.1    Chiueh, C.C.2
  • 28
    • 0024368622 scopus 로고
    • 6-Hydroxydopamine releases iron from ferritin and promotes ferritin-dependent lipid peroxidation
    • Monteiro H. P. and Winterbourn C. C. (1989) 6-Hydroxydopamine releases iron from ferritin and promotes ferritin-dependent lipid peroxidation. Biochem. Pharmacol. 38, 4177-4182.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 4177-4182
    • Monteiro, H.P.1    Winterbourn, C.C.2
  • 30
    • 0022400573 scopus 로고
    • Partial protection from the dopaminergic neurotoxin MPTP by four different antioxidants in the mouse
    • Perry T. L., Yong V. W., Clavier R. M., Jones K., Wright J. M., Foulks J. G., and Wall R. A. (1985) Partial protection from the dopaminergic neurotoxin MPTP by four different antioxidants in the mouse. Neurosci. Lett. 60, 109-114.
    • (1985) Neurosci. Lett. , vol.60 , pp. 109-114
    • Perry, T.L.1    Yong, V.W.2    Clavier, R.M.3    Jones, K.4    Wright, J.M.5    Foulks, J.G.6    Wall, R.A.7
  • 31
    • 0022496317 scopus 로고
    • Monoamine oxidase activity and monoamine metabolism in brains of parkinsonian patients treated with l-deprenyl
    • Riederer P. and Youdim M. B. H. (1986) Monoamine oxidase activity and monoamine metabolism in brains of parkinsonian patients treated with l-deprenyl. J. Neurochem. 46, 1359-1365.
    • (1986) J. Neurochem. , vol.46 , pp. 1359-1365
    • Riederer, P.1    Youdim, M.B.H.2
  • 33
    • 0023895945 scopus 로고
    • The use of in vivo dialysis of dopamine, acetylcholine, aminoacids and lactic acid in studies on the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
    • Rollema H., De Vries J. B., Damsma G., Westerink B. H. C., Kranenborg G. L., Kuhr W. G., and Horn A. S. (1988) The use of in vivo dialysis of dopamine, acetylcholine, aminoacids and lactic acid in studies on the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Toxicology 49, 503-511.
    • (1988) Toxicology , vol.49 , pp. 503-511
    • Rollema, H.1    De Vries, J.B.2    Damsma, G.3    Westerink, B.H.C.4    Kranenborg, G.L.5    Kuhr, W.G.6    Horn, A.S.7
  • 34
    • 0025152991 scopus 로고
    • Characterization of the in vivo release of dopamine as recorded by different types of intracerebral microdialysis probes
    • Santiago M. and Westerink B. H. C. (1990) Characterization of the in vivo release of dopamine as recorded by different types of intracerebral microdialysis probes. Naunyn Schmiedebergs Arch. Pharmacol. 342, 407-414.
    • (1990) Naunyn Schmiedebergs Arch. Pharmacol. , vol.342 , pp. 407-414
    • Santiago, M.1    Westerink, B.H.C.2
  • 35
    • 0026060876 scopus 로고
    • + on nigral and bilateral striatal release of dopamine simultaneously recorded by microdialysis
    • + on nigral and bilateral striatal release of dopamine simultaneously recorded by microdialysis. Brain Res. 538, 226-230.
    • (1991) Brain Res. , vol.538 , pp. 226-230
    • Santiago, M.1    Rollema, H.2    De Vries, J.B.3    Westerink, B.H.C.4
  • 36
    • 0025980949 scopus 로고
    • Responsiveness of striatal dopamine release in awake animals after chronic 1-methyl-4-phenylpyridinium ion-induced lesions of the substantia nigra
    • Santiago M., Westerink B. H. C., and Rollema H. (1991b) Responsiveness of striatal dopamine release in awake animals after chronic 1-methyl-4-phenylpyridinium ion-induced lesions of the substantia nigra. J. Neurochem. 56, 1336-1342.
    • (1991) J. Neurochem. , vol.56 , pp. 1336-1342
    • Santiago, M.1    Westerink, B.H.C.2    Rollema, H.3
  • 37
    • 0022347630 scopus 로고
    • Protection against MPTP neurotoxicity by the antioxidant ascorbic acid
    • Sershen H., Reith M. E. A., Hashim A., and Lajtha A. (1985) Protection against MPTP neurotoxicity by the antioxidant ascorbic acid. Neuropharmacology 24, 1257-1259.
    • (1985) Neuropharmacology , vol.24 , pp. 1257-1259
    • Sershen, H.1    Reith, M.E.A.2    Hashim, A.3    Lajtha, A.4
  • 39
    • 0023833504 scopus 로고
    • +) in the neostriatum of the rat as demonstrated in vivo by the push-pull perfusion technique: Dependence on sodium but not calcium ions
    • +) in the neostriatum of the rat as demonstrated in vivo by the push-pull perfusion technique: dependence on sodium but not calcium ions. Brain Res. 443, 101-106.
    • (1988) Brain Res. , vol.443 , pp. 101-106
    • Sirinathsinghji, D.J.S.1    Heavens, R.P.2    McBride, C.S.3
  • 41
    • 0028798434 scopus 로고
    • Oxidative mechanisms in the toxicity of metal ions
    • Stohns S. J. and Bagchi D. (1995) Oxidative mechanisms in the toxicity of metal ions. Free Radic. Biol. Med. 18, 321-336.
    • (1995) Free Radic. Biol. Med. , vol.18 , pp. 321-336
    • Stohns, S.J.1    Bagchi, D.2
  • 42
    • 0019083215 scopus 로고
    • Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria
    • Turrens J. F. and Boveris A. (1980) Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria. Biochem. J. 191, 421-427.
    • (1980) Biochem. J. , vol.191 , pp. 421-427
    • Turrens, J.F.1    Boveris, A.2
  • 43
    • 0022352138 scopus 로고
    • Ascorbic acid reduces dopamine depletion induced by MPTP
    • Wegner G. C., Jarvis M. F., and Carelli R. M. (1985) Ascorbic acid reduces dopamine depletion induced by MPTP. Neuropharmacology 24, 1261-1262.
    • (1985) Neuropharmacology , vol.24 , pp. 1261-1262
    • Wegner, G.C.1    Jarvis, M.F.2    Carelli, R.M.3
  • 44
    • 0023499635 scopus 로고
    • Scope and limitations of in vivo brain dialysis: A comparison of its application to various neurotransmitter systems
    • Westerink B. H. C., Damsma G., Rollema H., De Vries J. B., and Horn A. S. (1987) Scope and limitations of in vivo brain dialysis: a comparison of its application to various neurotransmitter systems. Life Sci. 41, 1763-1776.
    • (1987) Life Sci. , vol.41 , pp. 1763-1776
    • Westerink, B.H.C.1    Damsma, G.2    Rollema, H.3    De Vries, J.B.4    Horn, A.S.5
  • 46
    • 0022650447 scopus 로고
    • Depletion of glutathione in brainstem of mice caused by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is prevented by antioxidant pretreatment
    • Yong V. W., Perry T. L., and Krisman A. A. (1986) Depletion of glutathione in brainstem of mice caused by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is prevented by antioxidant pretreatment. Neurosci. Lett. 63, 56-60.
    • (1986) Neurosci. Lett. , vol.63 , pp. 56-60
    • Yong, V.W.1    Perry, T.L.2    Krisman, A.A.3
  • 47
    • 0027351360 scopus 로고
    • The neurotoxicity of iron and nitric oxide: Relevance to the etiology of Parkinson's disease
    • (Narabayashi H., Nagatsu T., Yanagisawa N., and Mizuno Y., eds). Raven Press, New York
    • Youdim M. B. H., Ben-Shachar D., Eshel G., Finberg J. P. M., and Riederer P. (1993) The neurotoxicity of iron and nitric oxide: relevance to the etiology of Parkinson's disease, in Advances in Neurology, Vol. 60 (Narabayashi H., Nagatsu T., Yanagisawa N., and Mizuno Y., eds). pp. 259-266. Raven Press, New York.
    • (1993) Advances in Neurology , vol.60 , pp. 259-266
    • Youdim, M.B.H.1    Ben-Shachar, D.2    Eshel, G.3    Finberg, J.P.M.4    Riederer, P.5
  • 48
    • 0010471495 scopus 로고
    • Cellular defences against damage from reactive oxygen species
    • Yu B. P. (1994) Cellular defences against damage from reactive oxygen species. Physiol. Rev. 74, 139-162.
    • (1994) Physiol. Rev. , vol.74 , pp. 139-162
    • Yu, B.P.1


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