메뉴 건너뛰기




Volumn 25, Issue 1, 1997, Pages 40-46

Pharmacokinetics and metabolism of the novel anticonvulsant agent N- (2,6-dimethylphenyl)-5-methyl-3-isoxazolecarboxamide (D2624) in rats and humans

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; D 2624; D 3017; D 3270; UNCLASSIFIED DRUG;

EID: 0031012605     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (18)

References (12)
  • 3
    • 0026697933 scopus 로고
    • New N-aryl isoxazolecarboxamides and N-isoxazolylbenzamides as anticonvulsant agents
    • F. Lepage, F. Tombret, G. Cuvier, A. Marivain, and J. M. Gillardin: New N-aryl isoxazolecarboxamides and N-isoxazolylbenzamides as anticonvulsant agents. Eur. J. Med. Chem. 27, 581-593 (1992).
    • (1992) Eur. J. Med. Chem. , vol.27 , pp. 581-593
    • Lepage, F.1    Tombret, F.2    Cuvier, G.3    Marivain, A.4    Gillardin, J.M.5
  • 4
    • 0342784621 scopus 로고
    • Comparison of anticonvulsant profile of lidocaine and a new structurally related N-aryl isoxazolecarboxamide (D2624)
    • J. M. Gillardin, M. Verleye, P. Girard, and F. Lepage: Comparison of anticonvulsant profile of lidocaine and a new structurally related N-aryl isoxazolecarboxamide (D2624). Epilepsia 34 (Suppl. 2), 94 (1993).
    • (1993) Epilepsia , vol.34 , Issue.2 SUPPL. , pp. 94
    • Gillardin, J.M.1    Verleye, M.2    Girard, P.3    Lepage, F.4
  • 5
    • 0015289935 scopus 로고
    • The tissue distribution, metabolism and excretion of lidocaine in rats, guinea pigs, dogs and man
    • J. B. Keenaghan and R. N. Boyes: The tissue distribution, metabolism and excretion of lidocaine in rats, guinea pigs, dogs and man. J. Pharmacol. Exp. Ther. 180, 454-463 (1972).
    • (1972) J. Pharmacol. Exp. Ther. , vol.180 , pp. 454-463
    • Keenaghan, J.B.1    Boyes, R.N.2
  • 8
    • 2042524507 scopus 로고
    • Useful procedures for the oxidation of alcohols involving pyridinium dichromate in a protic media
    • E. J. Corey and G. Schmidt: Useful procedures for the oxidation of alcohols involving pyridinium dichromate in a protic media. Tetrahedron Lett. 5, 399-402 (1979).
    • (1979) Tetrahedron Lett. , vol.5 , pp. 399-402
    • Corey, E.J.1    Schmidt, G.2
  • 9
    • 33845374026 scopus 로고
    • Selective oxidation of aldehydes to carboxylic acids with sodium chlorite-hydrogen peroxide
    • E. Dalcanale and F. Montanari: Selective oxidation of aldehydes to carboxylic acids with sodium chlorite-hydrogen peroxide. J. Org. Chem. 51, 567-569 (1986).
    • (1986) J. Org. Chem. , vol.51 , pp. 567-569
    • Dalcanale, E.1    Montanari, F.2
  • 10
    • 0001536907 scopus 로고
    • Ortho alkylation of acetanilides using alkyl halides and palladium acetate
    • S. J. Tremont and H. U. Rahman: Ortho alkylation of acetanilides using alkyl halides and palladium acetate. J. Am. Chem. Soc. 106, 5759-5760 (1984).
    • (1984) J. Am. Chem. Soc. , vol.106 , pp. 5759-5760
    • Tremont, S.J.1    Rahman, H.U.2
  • 11
    • 0023140198 scopus 로고
    • Acetylation in aqueous solution and identification of derivatives by combined gas chromatography/mass spectrometry
    • R. T. Coutts, G. A. Torok-Both, Y. K. Tam, L. V. Chu, and F. M. Pasutto: Acetylation in aqueous solution and identification of derivatives by combined gas chromatography/mass spectrometry. Biomed. Environ. Mass. Spectrom. 14, 173-182 (1987).
    • (1987) Biomed. Environ. Mass. Spectrom. , vol.14 , pp. 173-182
    • Coutts, R.T.1    Torok-Both, G.A.2    Tam, Y.K.3    Chu, L.V.4    Pasutto, F.M.5
  • 12
    • 0027417453 scopus 로고
    • Human liver microsomal enflurane defluorination catalyzed by P-450 2E1
    • K. E. Thummel, E. D. Kharasch, T. Podoll, and K. Kunze: Human liver microsomal enflurane defluorination catalyzed by P-450 2E1. Drug Metab. Dispos. 21, 350-357 (1993).
    • (1993) Drug Metab. Dispos. , vol.21 , pp. 350-357
    • Thummel, K.E.1    Kharasch, E.D.2    Podoll, T.3    Kunze, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.