A short synthesis of an important precursor to a new class of bicyclic β-lactamase inhibitors

Tetrahedron Letters

Volumn 38, Issue 2, 1997, Pages 167-168

  Bellettini, John R ^a   Miller, Marvin J ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE INHIBITOR;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0031012468     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(96)02264-2     Document Type: Article

References (7)

1. Davies, J. Science 1994, 264, 375-382.
2. (a) Angehrn, P.; Gubernator, K.; Gutknecht, E.-M.; Heinze-Krauss, I.; Hubschwerlen, C.; Kania, M.; Page, M. G. P.; Specklin, J.-L. 35th Interscience Conference on Antimicrobial Agents and Chemotherapy 1995, Program and Abstracts, F147.
3. (b) Charnas, R.; Gubernator, K.; Heinze, I.; Hubschwerlen, C. European patent serial No. 0508234A2 1992.
4. Miller, M. J. Acc. Chem. Res. 1986, 19, 49-56.
5. (a) Mitsunobu, O. Synthesis 1981, 1-28.
6. (b) Hughes, D. L. Org. React. 1992, 42, 335-656.
7. 4: C, 64.13; H, 6.97; N, 8.80. Found: C, 63.92, H, 6.99; N, 8.70.