Peripheral benzodiazepine receptors in isolated human pancreatic islets

Journal of Cellular Biochemistry

Volumn 64, Issue 2, 1997, Pages 273-277

  Giusti, Laura ^a   Marchetti, Piero ^a   Trincavelli, Letizia ^a   Lupi, Roberto ^a   Martini, Claudia ^a   Lucacchini, Antonio ^a   Del Guerra, Silvia ^a   Tellini, Cristina ^a   Carmellini, Mario ^a   Navalesi, Renzo ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

3H PK 11195; human islets; insulin release; peripheral benzodiazepine receptor; Ro 5 4864

Indexed keywords

BENZODIAZEPINE RECEPTOR;

ARTICLE; BINDING SITE; HUMAN; HUMAN TISSUE; INSULIN RELEASE; PANCREAS ISLET; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION;

BENZODIAZEPINONES; HUMANS; ISLETS OF LANGERHANS; ISOQUINOLINES; RECEPTORS, GABA-A;

EID: 0031012457     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(199702)64:2<273::AID-JCB10>3.0.CO;2-K     Document Type: Article

References (25)

1. Anholt RRH, Pedersen PL, De Souza EB, Snyder SH (1986): The peripheral-type benzodiazepine receptor: Localization to the mitochondrial outer membrane. J Biol Chem 261:576-580.
2. 3H] PK-11195 to cerebral cortex and peripheral tissues of various species: Species differences and heterogeneity in peripheral benzodiazepine binding sites. J Neurochem 49:1407-1414.
3. 3H]PK-11195 and autoradiographic localization. Arch Int Pharmacodyn 266:38-49.
4. 3H]-diazepam binding. Proc Natl Acad Sci U S A 74:3805-3809.
5. Broaddus WC, Bennett JP Jr (1990): Peripheral-type benzodiazepine receptors in human glioblastomas: Pharmacologic characterization and photoaffinity labelling of ligand recognition site. Brain Res 518:199-208.
6. Camins A, Sureda FX, Pubill D, Camarasa J, Escubedo E (1994): Characterization and differentiation of peripheral-type benzodiazepine receptors in rat and human pros-tate. Life Sci 54:759-767.
7. 50) of an enzymatic reaction. Biochem Pharmacol 22:3099-3108.
8. Cosimi S, Giusti L, Marchetti P, Trincavelli L, Giannarelli R, Martini C, Arvia C, Lucacchini A, Navalesi R (1994): Benzodiazepine receptors in porcine pancreatic islets. Diabetologia 37(Suppl. 1):A111.
9. De Souza E, Anholt R, Murphy K, Snyder SH, Kuhar M (1985): Peripheral-type benzodiazepine receptor in endocrine organs: Autoradiographic localization in rat pituitary, adrenal and testis. Endocrinology 116:567-573.
10. Giusti L, Trincavelli L, Martini C, Lucacchini A (1994): Characterization of peripheral-type benzodiazepine binding sites from rat and pig pancreas. Biochem Pharmacol 48:583-586.
11. Katay Z, Eitan A, Gavish M (1990): Increase in peripheral benzodiazepine binding sites in colonic adenocarcinoma. Oncology 47:139-142.
12. Leatebarrow RJ (1992) GraFit, version 3.0. Staines, UK: Erithacus Software Ltd.
13. 3H] PK-11195, by thermodynamic studies. Life Sci 33:449-457.
14. Lenfant M, Haumont J, Zavola F, Potier P (1985): Relations between the nervous system and the immune system: Some examples. Bull Acad Natl Med 169:1005-1011.
15. Marchetti P, Giannarelli R, Velani G, Andreazzi M, Cruschelli L, Cosimi S, Viacava P, diCarlo A, Bevilacqua G, Navalesi R (1994): Collagenase distension, to-step sequenzial filtration, and Histopaque gradient purification for consistent isolation of pure pancreatic islets from the market-age (6-month-old) pig. Transplantation 57:1532-1535.
16. Marchetti P, Giannarelli R, Cosimi S, Masiello P, Coppelli A, Viacava P, Navalesi R (in press): Massive isolation, morphological and functional characterization, and xenotransplantation of bovine pancreatic islets. Diabetes.
17. McEnery MW, Showman AM, Trifiletti RR, Snyder SH (1992): Isolation of the mitochondrial benzodiazepine receptor association with the voltage-dependent anion channel and the adenine nucleotide carrier. Proc Natl Acad Sci U S A 89:3170-3174.
18. Mohler H, Okada T (1977): Benzodiazepine receptors: Demonstration in the central nervous system. Science 198: 849-851.
19. Petit P, Manteghetti M, Berdeu D, Ribes G, Loubatières-Mariani MM (1992): Effects of the peripheral-type benzodiazepine on glucose induced insulin secretion. Eur J Pharmacol 221:359-363.
20. Ruff MR, Pert CB, Weber RJ, Wahl LM, Paul SM (1985): Benzodiazepine mediated chemiotaxis of human monocytes. Science 229:1281-1283.
21. 3H]Ro 5-4864 in rat brain and kidney. J Pharmacol Exp Ther 225:61-69.
22. 3H]Ro 5-4864 benzodiazepine binding in the kainate lesioned striatum and Huntington's diseased basal ganglia. Brain Res 248:396-401.
23. Skowronski RE, Beaumont K, Fanestil DD (1987): Modification of the peripheral-type benzodiazepine receptor by arachidonate, diethylpyrocarbonate and thiol reagents. Eur J Pharmacol 143:305-314.
24. Snyder SH, McEnery MW, Verma A (1990): Molecular mechanisms of peripheral benzodiazepine receptors. Neurochem Res 15:119-126.
25. Tallman JP, Paul SM, Skolnick P, Galla er DW (1980): Receptors for the age of anxiety: Pharmacology of the benzodiazepines. Science 207:274-281.