Comparative analysis of the gp120-binding area of murine and human CD4 molecules

Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology

Volumn 14, Issue 1, 1997, Pages 7-12

  Siddiqi, Mushtaq A ^a   Tachibana, Makoto ^a   Ohta, Sachiko ^a   Ikegami, Yuko ^a   Tahara Hanaoka, Satoko ^a   Huang, Yi Ying ^a   Shinohara, Nobukata ^a  

^a MITSUBISHI KASEI INST OF LIFE SCI   (Japan)

Author keywords

gp120; HIV; Human CD4; Murine CD4; Mutagenesis

Indexed keywords

CD4 ANTIGEN; GLYCOPROTEIN GP 120;

AMINO ACID SEQUENCE; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; HUMAN; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN TERTIARY STRUCTURE; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; VIRUS MUTATION;

MURINAE;

EID: 0031012275     PISSN: 10779450     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042560-199701010-00002     Document Type: Article

References (17)

1. + cells by a complex of the 110K viral protein and the T4 molecule. Science 1985:231:382-5.
2. Banda NK, Bernier J, Kurahara DK, et al. Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis. J Exp Med 1992;176:1099-106.
3. Rosenstein Y, Burakoff SJ, Herrmann SH. HIV-gpl20 can block CD4-class II MHC-mediated adhesion. J Immunol 1990;144:526-31.
4. McClure MO, Sattentau QJ, Beverley PCL, et al. HIV infection of primate lymphocytes and conservation of the CD4 receptor. Nature 1987;330:487-9.
5. Landau NR, Warton M, Littman DR. The envelope glycoprotein of the human immunodeficiency virus binds to the immunoglobulin-like domain of CD4. Nature 1988;334: 159-62.
6. Mizukami T, Fuerst TR, Berger EA, Moss B. Binding region for human immunodeficiency virus (HIV) and epitopes for HIV-blocking monoclonal antibodies of the CD4 molecule defined by site-directed mutagenesis. Proc Natl Acad Sci USA 1988;85:9273-7.
7. Arthos J, Deen KC, Chaikin MA, et al. Identification of the residues in human CD4 critical for the binding of HIV. Cell 1989:57:469-81.
8. Brodsky MH, Warton M, Myers RM, Littman DR. Analysis of the site in CD4 that binds to the HIV envelope glycoprotein. J Immunol 1990;144:3078-86.
9. Bowman MR, MacFerrin KD. Schreiber SL, Burakoff SJ. Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules. Proc Natl Acad Sci USA 1990:87:9052-6.
10. Ashikenazi A, Presta LG, Marsters SA. et al. Mapping the CD4 binding site for human immunodeficiency virus by alanine-scanning mutagenesis. Proc Natl Acad Sci USA 1990;87:7150-4.
11. Fleury S, Lanarre D, Meloche S, et al. Mutational analysis of the interaction between CD4 and class II MHC: class II antigens contact CD4 on a surface opposite the gp120-binding site. Cell 1991;66:1037-49.
12. Moebius U, Clayton LK, Abraham S, et al. Human immunodeficiency virus gp120 binding C′C″ ridge of CD4 domain 1 is also involved in interaction with class II major histocompatibility complex molecules. Proc Natl Acad Sci USA 1992; 89:12008-12.
13. Kunkel TA, Roberts JD, Zakour RA. Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc Natl Acad Sci USA 1985;82:488-92.
14. McDougal JS, Nicholson JKA, Cross GD, Cort SP, Kennedy MS, Mqwle AC. Binding of the human retrovirus HTLV-III/ LAV?ARV/HIV to the CD4 (T4) molecule: conformation dependence, epitope mapping antibody inhibition, and potential for idiotypic mimicry. J Immunol 1986;137:2937-44.
15. Ryu S-E, Kwong PD, Truneh A, et al. Crystal structure of an HIV-binding recombinant fragment of human CD4. Nature 1990;348:419-25.
16. Cordonnier A, Montagnier L, Emerman M. Single amino-acid changes in HIV envelope affect viral tropism and receptor binding. Nature 1989;340:571-4.
17. Olshevsky U, Helseth E, Furman C, Li J, Haseltine W, Sodroski J. Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding. J Virol 1990;64:5701-7.