Radioimmunoscintigraphy with Tc-99m labeled monoclonal antibody 170H.82 in suspected primary, recurrent, or metastatic breast cancer

Clinical Nuclear Medicine

Volumn 22, Issue 1, 1997, Pages 30-34

  Lind, Peter ^a   Gallowitsch, Hans Jürgen ^a   Mikosch, Peter ^a   Kresnik, Ewald ^a   Gomez, Iris ^a   Omann, Johann ^b   Dinges, Hans Peter ^a   Boniface, Graeme ^c  

^a Department of Nuclear Medicine ^*

^b GENERAL HOSPITAL KLAGENFURT   (Austria)

^c Biomira Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; TECHNETIUM 99M;

ADULT; AGED; ARTICLE; AXILLARY LYMPH NODE; BONE SCINTISCANNING; BREAST CANCER; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; HUMAN; IMMUNOSCINTIGRAPHY; LYMPH NODE METASTASIS; METASTASIS; NUCLEAR MAGNETIC RESONANCE IMAGING; SCAR; SCINTILLATION CAMERA;

BONE NEOPLASMS; BREAST NEOPLASMS; FEMALE; GAMMA CAMERAS; HUMANS; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; RADIOIMMUNODETECTION; SENSITIVITY AND SPECIFICITY; TECHNETIUM; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOMOGRAPHY, X-RAY COMPUTED;

EID: 0031012131     PISSN: 03639762     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003072-199701000-00007     Document Type: Article

References (20)

1. Allan, SM, Dean C, Fernando I, et al: Radioimmunoscintigraphy in breast cancer using the gene product of C-erb B2 as the target antigen. Brit J Cancer 67:706, 1993.
2. Epenetos A, Mather S, Granowska M, et al: Targeting of I-123 labelled tumor associated monoclonal antibodies to ovarian breast and gastrointestinal tumors. Lancet 8306:999, 1982.
3. Kairemo KJ: Immunolymphoscintigraphy with Tc-99m labelled monoclonal antibody (BW 431/26) reacting with carcinoembryonic antigen in breast cancer. Cancer Res (Supplement) 50: 949s, 1990.
4. Mandeville R, Pateisky N, Phillipp K, et al: Immunoscintigraphy of axillary lymph node metastases in breast cancer patients using monoclonal antibodies: first clinical findings. Anticancer Res 6:1257, 1986.
5. Athanassiou A, Pectasides B, Pateniotis K, et al: Immunoscintigraphy with I-131 labelled HMFG2 and HMFG1 (ab') 2 in the preoperative detection of clinical and subclinical lymph node metastases in breast cancer patients Int J Cancer (Supplement) 3:89, 1988.
6. Lind P, Smola MG, Lechner P, et al: The immunoscintigraphic use of Tc-99m labelled monoclonal anti-CEA antibodies (BW 43l/ 26) in patients with suspected primary recurrent metastatic breast cancer. Int J Cancer 47:865, 1991.
7. Lind P, Lechner P, Hausmann B, et al: Development of human antimouse antibodies (HAMA) after single and repeated diagnostic application of intact murine monoclonal antibodies Antibody Immunoconj Radiopharm 4:811, 1991.
8. M): A monoclonal antibody for the evaluation of patients with breast cancer - a preliminary analysis. J Nucl Med 5:213, 1993.
9. Hayes BF, Zalutsky MR, Kaplan W et al: Pharmacokinetics of radiolabelled monoclonal antibody B6.2 in patients with metastatic breast cancer. Cancer Res 46:3957, 1986.
10. Riva P, Moscatelli G, Paganelli G. et al: Antibody guided diagnosis: An Italian experience on CEA expressing tumors. Int J Cancer 2:114, 1988.
11. Mc Ewan AJB, Mc Lean GD, Hooper HR, et al: MAb 170H.82: an evaluation of a novel panadenocarcinoma monoclonal antibody labelled with Tc-99m and In-111. Nucl Med Comun 13:11, 1992.
12. Duncker CM, Carrio I, Berna L, et al: Radioimmunoimaging of bone marrow in patients with suspected bone metastases from primary breast cancer J Nucl Med 31:1450, 1990.
13. Reske SN: Recent advances in bone marrow imaging. Eur J Nucl Med 18:203, 1991.
14. Sacchi S, Marietta M, Rinaldi D, et al: Bone and bone marrow scintigraphy in the diagnosis of neoplastic involvement of the skeletal system. J Nucl Med 31:255, 1987.
15. Baum RP, Hertel A, Lorenz M, et al: Tc-99m labeled anti CEA monoclonal antibody for tumor immunoscintigraphy: first clinical results. Nucl Med Comun 10:345, 1989.
16. Hertel A, Baum RP, Auerbach B. et al: Klinische Relevanz humaner Antimaus-Antikörper in der Immunscintigraphie. Nucl Med 29:221, 1990.
17. Becker W, Scheele J, Feistel H et al: Sensitivity of Tc-99m anti CEA MAb scans in recurrence and metastases of colorectal cancer depending on imaging technique and CEA serum levels. In: Schmidt HEA, Chambron J (eds): Nuclear Medicine. Stuttgart: Schattauer 1990, pp 535-537.
18. IS. Bischof-Delaloye A, Delaloye B, Buchegger F. et al: Clinical value of immunoscintigraphy in colorectal carcinoma patients: a prospective study. J Nucl Med 30:1646, 1989.
19. Buraggi G, Turrin A. Bombardi E, et al: Immunoscintigraphy of colorectal carcinoma with F (ab)2 fragment of anti CEA monoclonal antibody. Cancer Detect Prevent 10:335, 1987.
20. Lind P, Lechner P, Arian-Schad K, et al: Anti carcinoembryonic antigen immunoscintigraphy (Tc-99m MAb BW 431/26) and serum CEA levels in patients with suspected primary and recurrent colorectal carcinoma. J Nucl Med 32:1319, 1991.