Compatibility of granisetron hydrochloride with selected drugs during simulated Y-site administration

American Journal of Health-System Pharmacy

Volumn 54, Issue 1, 1997, Pages 56-60

  Trissel, Lawrence A ^a,b   Gilbert, Doward L ^a   Martinez, Juan F ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Additives; Amphotericin B; Amsacrine; Anti infective agents; Antiemetics; Antineoplastic agents; Dextrose; Diluents; Granisetron hydrochloride; Incompatibilities; Injections; Precipitation; Sodium chloride; Stability; Storage; Turbidity

Indexed keywords

ALLOPURINOL; ANTIBIOTIC AGENT; ANTIEMETIC AGENT; ANTINEOPLASTIC AGENT; BICARBONATE; CEFAZOLIN; CEFEPIME; CEFONICID; CLINDAMYCIN PHOSPHATE; DILUENT; DOPAMINE; DROPERIDOL; FLUOROURACIL; GLUCONATE CALCIUM; GRANISETRON; HEPARIN; HYDROCORTISONE SODIUM SUCCINATE; IDARUBICIN; INFUSION FLUID; MAGNESIUM SULFATE; MELPHALAN; METHYLPREDNISOLONE SODIUM SUCCINATE; METOCLOPRAMIDE; MITOMYCIN; NALBUPHINE; NAVELBINE; TENIPOSIDE; TICARCILLIN; TIMENTIN; UNINDEXED DRUG;

ARTICLE; DRUG INCOMPATIBILITY; DRUG MIXTURE; PRECIPITATION; PRIORITY JOURNAL; SIMULATION;

EID: 0031012077     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajhp/54.1.56     Document Type: Article

References (7)

1. Kytril package insert. Philadelphia: SmithKline Beecham Pharmaceuticals; 1994 Feb.
2. Trissel LA, Martinez JF. Compatibility of granisetron hydrochloride with alkaline drugs. Am J Health-Syst Pharm. 1995; 52:208. Letter.
3. Mayron D, Gennaro AR. Stability and compatibility of granisetron hydrochloride in i.v. solutions and oral liquids and during simulated Y-site injection. Am J Health-Syst Pharm. 1996; 53:294-304.
4. Allen LV Jr, Levinson RS, Phisutsinthop D, Compatibility of various admixtures with secondary additives at Y-injection sites of intravenous administration sets. Am J Hosp Pharm. 1977; 34:939-43.
5. Trissel LA, Martinez JF. Physical compatibility of melphalan with selected drugs during simulated Y-site administration. Am J Hosp Pharm. 1993; 50:2359-63.
6. Trissel LA, Bready BB. Turbidimetric assessment of the compatibility of taxol with selected other drugs during simulated Y-site injection. Am J Hosp Pharm. 1992; 49:1716-9.
7. Trissel LA, Martinez JF. Turbidimetric assessment of the compatibility of taxol with selected other drugs during simulated Y-site injection, part 2. Am J Hosp Pharm. 1993; 50:300-4.