Kinetics of retinyl esters during postprandial lipemia in man: A compartmental model

Metabolism: Clinical and Experimental

Volumn 46, Issue 5, 1997, Pages 584-594

  Le, Ngoc Anh ^a   Coates, Paul M ^b   Gallagher, Paul R ^b   Cortner, Jean A ^b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

RETINOL ESTER;

ADULT; ARTICLE; CLINICAL ARTICLE; COMPARTMENT MODEL; CONTROLLED STUDY; HUMAN; HYPERLIPIDEMIA; POSTPRANDIAL STATE; PRIORITY JOURNAL; REPRODUCIBILITY; VITAMIN METABOLISM;

EID: 0031010673     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(97)90198-0     Document Type: Article

References (46)

1. Robinson DS: Function of plasma triglycerides in fatty acid transport, in Florkin M, Stotz EH (eds): Comprehensive Biochemistry. Amsterdam, The Netherlands, Elsevier, 1970, pp 51-116
2. Redgrave TG: Formation of cholesteryl ester-rich particulate lipid during metabolism of chylomicron. J Clin Invest 49:465-471, 1970
3. Bierman EL, Gordis E, Hamlin JT: Heterogeneity of fat particles during alimentary hyperlipemia. J Clin Invest 41:2254-2261, 1962
4. Bierman EL, Hayes TL, Hawkins JN, et al: Particle-size distribution of very low density plasma lipoproteins during fat absorption in man. J Lipid Res 7:65-72, 1966
5. Grundy SM, Mok HYI: Chylomicron clearance in normal and hyperlipidemic man. Metabolism 25:1225-1239, 1976
6. Green PHR, Glickman RM: Intestinal lipoprotein metabolism. J Lipid Res 22:1153-1173, 1981
7. Redgrave TG: Formation and metabolism of chylomicron. Int Rev Physiol 28:103-130, 1983
8. Bergman EN, Havel RJ, Wolfe BM, et al: Quantitative studies of the metabolism of chylomicron triglycerides and cholesterol by liver and extrahepatic tissues of sheep and dogs. J Clin Invest 50:1831-1839, 1971
9. Sherrill BC, Dietschy JM: Characterization of the sinusoidal transport process responsible for uptake of chylomicron by the liver. J Biol Chem 253:1859-1867, 1978
10. Sherrill BC, Innerarity TL, Mahley RW: Rapid hepatic clearance of the canine lipoproteins containing only the E apolipoprotein by a high affinity receptor: Identity with the chylomicron remnant transport process. J Biol Chem 255:1804-1807, 1980
11. Hui DY, Innerarity TL, Mahley RW: Lipoprotein binding to canine hepatic membranes. J Biol Chem 256:5646-5655, 1981
12. Zilversmit DB: A proposal linking atherogenesis to the interaction of endothelial lipoprotein lipase with triglyceride-rich lipoproteins. Circ Res 33:633-637, 1973
13. Zilversmit DB: Atherogenesis: A postprandial phenomenon. Circulation 60:473-485, 1979
14. Hazzard WR, Bierman EL: Delayed clearance of chylomicron remnants following vitamin-A - containing oral fat loads in broad-B disease (type III hyperlipoproteinemia). Metabolism 25:777-801, 1976
15. Goodman DS, Bloomstrand R, Werner B, et al: The intestinal absorption and metabolism of vitamin A and beta-carotene in man. J Clin Invest 45:1615-1623, 1966
16. Goodman DS, Huang HS, Shiratori T: Tissue distribution and metabolism of newly absorbed vitamin A in the rat. J Lipid Res 6:390-396, 1965
17. Wilson DE, Chan IF, Ball M: Plasma lipoprotein retinoids after vitamin A feeding in normal man: Minimal appearance of retinyl esters among low density lipoproteins. Metabolism 32:514-517, 1983
18. Wilson DE, Chan IF, Buchi KN, et al: Postchallenge plasma lipoprotein retinoids: Chylomicron remnants in endogenous hypertriglyceridemia. Metabolism 34:551-558, 1985
19. Wilson DE, Chan IF, Cheung AK, et al: Retinyl ester retention in chronic renal failure. Further evidence for a defect in chylomicron remnant metabolism. Atherosclerosis 5:187-189, 1985
20. Berr F, Kern F: Plasma clearance of chylomicron labeled with retinyl palmitate in healthy human subjects. J Lipid Res 25:805-812, 1984
21. Berr F, Eckel R, Kern F: Plasma decay of chylomicron remnants is not affected by heparin-stimulated plasma lipolytic activity in normal fasting man. J Lipid Res 26:852-859, 1985
22. Cortner JA, Coates PM, Le NA, et al: Kinetics of chylomicron remnant clearance in normal and hyperlipoproteinemic subjects. J Lipid Res 28:195-206, 1987
23. Weintraub MS, Eisenberg S, Breslow JL: Different patterns of postprandial lipoprotein metabolism in normal, type IIa, type III, and type IV hyperlipoproteinemic individuals. Effects of treatment with cholestyramineandgemfibrozil. J Clin Invest 79:1110-1119, 1987
24. Weintraub MS, Eisenberg S, Breslow JL: Dietary fat clearance in normal subjects is regulated by genetic variation in apolipoprotein E. J Clin Invest 80:1571-1577, 1987
25. Genest J, Sniderman A, Cianflone K, et al: Hyperapobetalipoproteinemia. Plasma lipoprotein responses to oral fat load. Arteriosclerosis 6:297-304, 1986
26. Krasinski SD, Cohn JS, Shaefer EJ, et al: Postprandial plasma retinyl ester response is greater in older subjects compared with younger subjects. J Clin Invest 85:883-892, 1990
27. Sprecher DL, Knauer SL, Black DM, et al: Chylomicron-retinyl palmitate clearance in type I hyperlipidemic families. J Clin Invest 88:985-994, 1991
28. Groot PHE, Van Stipthout WA, Krauss XH, et al: Postprandial lipoprotein metabolism in normolipidemic men with and without coronary artery disease. Arterioscler Thromb 11:653-662, 1991
29. Cohen JC, Noakes TD, Spinnler-Benade AJ: Serum triglyceride responses to fatty meals: Effects of meal fat content. Am J Clin Nutr 47:825-827, 1988
30. Weintraub MS, Zechner R, Brown A, et al: Dietary polyunsaturated fat of the w-6 and w-3 series reduce postprandial lipoprotein levels. J Clin Invest 82:1884-1893, 1988
31. Berman M, MF Weiss: SAAM Manual. DHEW, NIH Publication No. 78-180, Washington, DC, US Government Printing Office, 1978
32. Berman M, Beltz WF, Grief RC, et al: CONSAM User's Guide. US Department of Health and Human Services, Washington, DC, US Government Printing Office, 1983
33. Ruotolo G, Zhang H, Bentsianov V, et al: Protocol for the study of the metabolism of retinyl esters in plasma lipoproteins during postprandial lipemia. J Lipid Res 33:1541-1549, 1992
34. Cortner JA, Le N-A, Coates PM, et al: Determinants of fasting plasma triglyceride levels: Metabolism of hepatic and intestinal lipoproteins. Eur J Clin Invest 22:158-162, 1992
35. Tytgat GN, Rubin CE, Saunders DR: Synthesis and transport of lipoprotein particles by intestinal absorptive cells in man. J Clin Invest 50:2065-2078, 1971
36. Zech LA, Grundy SM, Steinberg D, et al: Kinetic model for production and metabolism of VLDL triglycerides. Evidence for a slow production pathway and results for normolipidemic subjects. J Clin Invest 63:1262-1273, 1979
37. Musliner TA, Herbert PN, Kingston MJ: Lipoprotein substrates for lipoprotein lipase and hepatic triacylglycerol lipase from human post heparin plasma. Biochim Biophys Acta 575:277-288, 1979
38. Nicoll A, Lewis B: Evaluation of the roles of lipoprotein lipase and hepatic lipase in lipoprotein metabolism: In vivo and in vitro studies in man. Eur J Clin Invest 10:487-495, 1980
39. Packard CJ, Munzo A, Lorimer AR, et al: Metabolism of apolipoprotein B in large triglyceride rich very low density lipoproteins of normal and hypertriglyceridemic subjects. J Clin Invest 74:2178-2192, 1984
40. Le N-A, Cortner JA, Breslow JL: Metabolism of intestinal lipoproteins during the postprandial state, in Rifkin H, Colwell JA, Taylor SI (eds): Diabetes 1991. New York, NY, Elsevier Science, 1991, pp 601-608
41. Le N-A, Innis W, Umeakunne K, et al: Accelerated clearance of postprandial lipoproteins with HMG-CoA reductase inhibitor. J Invest Med 43:301A, 1995 (abstr)
42. Sweeney ME, Le N-A, Li X, et al: Effect of weight loss on LDL particle size and postprandial lipemia in obese subject with CAD. Circulation 88:1364, 1993 (abstr)
43. Cohn JS, McNamara JR, Krasinski SD, et al: Role of triglyceriderich lipoproteins from the liver and intestine in the etiology of post-prandial peaks in plasma triglyceride concentration. Metabolism 38:484-490, 1989
44. Cohn JS, Johnson EJ, Millar JS, et al: Contribution of apoB-48 and apoB-100 triglyceride-rich lipoproteins to postprandial increases in the plasma concentration of TRL triglycerides and retinyl esters. J Lipid Res 34:2033-2040, 1993
45. Vega GL, Beltz WF, Grundy SM: Low density lipoprotein metabolism in hypertriglyceridemic and normolipidemic patients with coronary heart disease. J Lipid Res 26:115S-126S, 1985
46. Sharrett AR, Chambless LE, Heiss G, et al: Association of postprandial triglyceride and retinyl palmitate responses with asymptomatic carotid artery atherosclerosis in middle-aged men and women. Arterioscler Thromb Vasc Biol 15:2122-2129, 1995