Enhancement of therapeutic efficacy of bleomycin by incorporation into biodegradable poly-d,l-lactic acid

Cancer Chemotherapy and Pharmacology

Volumn 40, Issue 2, 1997, Pages 112-116

  Kumanohoso, Toru ^a   Natsugoe, Shoji ^a   Shimada, Mario ^a   Aikou, Takashi ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Bleomycin; Drug delivery system; Locoregional chemotherapy; Polylactic acid

Indexed keywords

BLEOMYCIN; POLYLACTIC ACID;

ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BIOASSAY; BIOAVAILABILITY; CONNECTIVE TISSUE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG RELEASE; DRUG TARGETING; IN VITRO STUDY; LYMPH NODE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; YOSHIDA SARCOMA;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BIODEGRADATION, ENVIRONMENTAL; BLEOMYCIN; DRUG DELIVERY SYSTEMS; DRUG IMPLANTS; LACTIC ACID; MALE; POLYMERS; RATS; SARCOMA, YOSHIDA;

EID: 0031010636     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050634     Document Type: Article

References (20)

1. Chen Y, Burton MA, Codde JP, Napoli S, Martins IJ, Gray BN (1992) Evaluation of ion-exchange microspheres as carriers for the anticancer drug doxorubicin: in-vitro studies. J Pharm Pharmacol 44: 211
2. Deurloo MJM, Bohlken S, Kop W, Lerk CF, Hennink W, Bartelink H , Begg AC (1990) Intratumourul administration of cisplatin in slow-release devices. Cancer Chemother Pharmacol 27: 135
3. Forssen EA, Coulter DM, Proffit RT (1992) Selective in vivo localization of daunorubicin small unilamellar vesicles in solid tumors. Cancer Res 52: 3255
4. Frei E, Canellos GP (1980) Dose: a critical factor in cancer chemotherapy. Am J Med 69: 585
5. Fukuzaki H, Yoshida M, Asano M, Kumakura,M (1989) Synthesis of copoly(d,1-lactic acid) with relatively low molecular weight and in vitro degradation. Eur Polym J 25: 1019
6. Fukuzaki H, Yoshida M, Asano M, Aiba Y, Kumakura M (1990) Direct copolymerization of glycolic acid with lactones in the absence of catalysts. Eur Polym J 26: 457
7. Grossman SA, Reinhard C, Colvin OM, Chasin M, Brundrett R, Tamargo RJ, Brem H (1992) The intracerebral distribution of BCNU delivered by surgically implanted biodegradable polymers. J Neurosurg 76: 640
8. Hagiwara A, Takahashi T, Kojima O, Kitamura K, Sakakura C, Shoubayashi S, Osaki K, Iwamoto A, Lee M, Fujita K (1993) Endoscopic local injection of a new drug-delivery format of peplomycin for superficial esophageal cancer: a pilot study. Gastroenterology 104: 1037
9. Hecquet B, Chabot F, Gonzalez JCD, Fournier C, Hilali S, Cambier L, Depadt G, Vert M (1986) In vivo sustained release of cisplatin from bioresorbable implants in mice. Anticancer Res 6: 1251
10. Imai R, Ashizawa T, Nakamura N (1975) An experimental postoperative metastasis system using Yoshida sarcoma inoculated subcutaneously into footpad. Gann 66: 69
11. Kumanohoso T, Natsugoe S, Shimada M, Sagara M, Aikou T, Shimazu H, Shinkawa T, Nakamura K, Fukuzaki H (1993) A basic study on usefulness of bleomycin incorporated in poly DL-lactic acid (in Japanese). Jpn J Cancer Chemother 20: 1572
12. Los G, Mutsaers PHA, Lenglet WJM, Baldew GS, McVie JG (1990) Platinum distribution in intraperitoneal tumors after intraperitoneal cisplatin treatment. Cancer Chemother Pharmacol 25: 389
13. Martini A, Torricelli C, Ponti RD (1991) Physico-pharmaceutical characteristics of steroid/crosslinked polyvinyl pyrrolidone coground systems. Int J Pharm 75: 141
14. Natsugoe S, Shimazu H, Yoshinaka H, Baba M, FukumotoT, Aikou T (1993) Recurrence of thoracic esophageal cancer after three-field lymphadenectomy. In: Nabeya K, Hanaoka T, Nogami H (eds), Recent advances in diseases of the esophagus. Springer, Tokyo, p 795
15. Schechter B, Wirchek M, Arnon R (1993) Increased therapeutic efficacy of cis-platinum complexes of poly-L-glutamic acid against a murine carcinoma. Int J Cancer 39: 409
16. Sharma A, Mayhew E, Straubinger RM (1993) Antitumor effect of taxol-containing liposomes in a taxol-resistant murine tumor model. Cancer Res 53: 5877
17. Shimada M, Natsugoe S, Kumanohoso T, Aikou T, Shimazu H. Nakamura K (1993) Local chemotherapy of esophageal cancer with bleomycin adsorbed to activated carbon particles. In: Nabeya K, Hanaoka T, Nogami H (eds) Recent advances in diseases of the esophagus. Springer, Tokyo, p 905
18. Theon AP, Pascoe JR, Carlson GP, Krag DN (1993) Intratumoral chemotherapy with cisplatin in oily emulsion in horses. J Am Vet Med Assoc 202: 261
19. Toguchi H (1992) Formulation study of leuprorelin acetate to improve clinical performance. Clin Ther 14: 121
20. Verrijk R, Smolders IJH, Bosnie N, Begg AC (1992) Reduction of systemic exposure and toxicity of cisplatin by encapsulation in poly-lactide-co-glycolide. Cancer Res 52: 6653