Clinical trial of a mucin-containing oral spray for treatment of xerostomia in hospice patients

Palliative Medicine

Volumn 11, Issue 3, 1997, Pages 225-232

  Sweeney, M P ^a   Bagg, J ^b   Baxter, W P ^c   Aitchison, T C ^d  

^a Renfrewshire Healthcare NHS Trust   (United Kingdom)

^b GLASGOW DENTAL HOSPITAL AND SCHOOL   (United Kingdom)

^c ACCORD Hospice   (United Kingdom)

^d UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Hospice care; Neoplasms; Oral health; Palliative treatment; Saliva; Saliva, artificial; Xerostomia

Indexed keywords

SALIVA SUBSTITUTE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; MALE; ORAL DRUG ADMINISTRATION; PALLIATIVE THERAPY; SALIVA; SELF MEDICATION; TERMINAL CARE; XEROSTOMIA;

EID: 0031010325     PISSN: 02692163     EISSN: None     Source Type: Journal    
DOI: 10.1177/026921639701100307     Document Type: Article

References (20)

1. Gordon SR, Berkey DB, Call RL. Dental needs among hospice patients in Colorado: a pilot study. Gerodontics 1985; 1: 125-29.
2. Aldred MJ, Addy M, Bagg J, Finlay I. Oral health in the terminally ill: a cross-sectional pilot survey. Spec Care Dent 1991; 11: 59-62.
3. Jobbins J, Bagg J, Finlay IG, Addy M, Newcombe RG. Oral and dental disease in terminally ill cancer patients. Br Med J 1992; 304: 1612.
4. Mandel ID. The functions of saliva. J Dent Res 1987; 66: 623-27.
5. Wright WE. Management of oral sequelae. J Dent Res 1987; 66: 699-702.
6. Renwick RA, Blasbere B, Patterson BD, Carmichael RP, Miles JE. Clinical aspects of xerostomia. J Clin Psychiatry 1983; 44: 63-65.
7. Jobbins J, Addy M, Bagg J, Finlay I, Parsons K, Newcombe RG. A clinical trial of chlorhexidine oral spray in terminally ill cancer patients. Palliat Med 1992; 6: 299-307.
8. Fox PC. Systemic therapy of salivary gland hypofunction. J Dent Res 1987; 66: 689-92.
9. Levine MJ, Aguirre A, Hatton MN, Tabak LA. Artificial saliva: present and future. J Dent Res 1987; 66: 693-98.
10. Duxbury AJ, Thakker NS, Wastell DG. A double-blind cross-over trial of a mucin-containing artificial saliva. Br Dent J 1989; 166: 115-20.
11. 's-Gravenmede EJ, Raukerna PA, Panders AK. The effect of mucin containing artificial saliva on severe xerostomia. Int J Oral Surg 1974; 3: 435-39.
12. 's-Gravenmede EJ, Panders AK. Clinical applications of saliva substitutes. Front Oral Physiol 1981; 3: 154-61.
13. Arendorf TM, Walker DM. Oral candidal populations in health and disease. Br Dent J 1979; 147: 267-72.
14. Samaranayake LP, MacFarlane TW, Williamson MI. Comparison of Sabouraud dextrose and Pagano-Levin agar media for detection and isolation of yeasts from oral samples. J Clin Microbiol 1987; 25: 162-64.
15. Risheim H, Arneberg P. Salivary stimulation by chewing gum and lozenges in rheumatic patients with xerostomia. Scand J Dent Res 1993; 101: 40-43.
16. Visch LL, 's-Gravenmede FJ, Schaub RMH, Van Putten WLJ, Vissink A. A double-blind crossover trial of CMC- and mucin-containing saliva substitutes. Int J Oral Maxillofac Surg 1986; 15: 395-400.
17. Bagg J. Can the colonisation resistance of the oral microflora be reduced? Microb Ecol Health Dis 1990; 3: v-viii.
18. Jobbins J, Bagg J, Parsons K, Finlay I, Addy M, Newcombe RG. Oral carriage of yeasts, coliforms and staphylococci in patients with advanced malignant disease. J Oral Pathol Med 1992; 21: 305-308.
19. Sweeney MP, Bagg J. Oral care for hospice patients with advanced cancer. Dent Update 1995; 22: 424-27.
20. Van Steenberghe D, Van den Eynde E, Jacobs R, Quirynen M. Effect of a lactoperoxidase containing toothpaste in radiation-induced xerostomia. Int Dent J 1994; 44: 133-38.