Hepatobiliary excretion of bile acids and rose bengal in streptozotocin- induced and genetic diabetic rats

Journal of Pharmacology and Experimental Therapeutics

Volumn 281, Issue 1, 1997, Pages 412-419

  Stone, Joy L ^a   Braunstein, Joel B ^a   Beaty, Timothy M ^a   Sanders, Ruth A ^a   Watkins III, John B ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); BILE ACID; ROSE BENGAL; STREPTOZOCIN; TAUROCHOLIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANION TRANSPORT; ARTICLE; BASOLATERAL MEMBRANE; BILE FLOW; BILIARY EXCRETION; CONTROLLED STUDY; DIABETES MELLITUS; INTRAHEPATIC BILE DUCT; LIVER CELL; LIVER CLEARANCE; MALE; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; BILE; BILE ACIDS AND SALTS; BILE CANALICULI; BIOLOGICAL TRANSPORT; CELL MEMBRANE; DIABETES MELLITUS, EXPERIMENTAL; LIVER; MALE; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; ROSE BENGAL; STREPTOZOCIN;

EID: 0031010251     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. ADACHI, Y., KOBAYASKI, H., KURMURI, Y., KITANO, M. AND YAMAMOTO, T.: ATP-dependent taurocholate transport by rat liver canalicular membrane vesicles. Hepatology 14: 655-659, 1991.
2. ADLER, R. D., WANNAGAT, F.-J. AND OCKNER, R. K.: Bile secretion in selective biliary obstruction: adaptation of taurocholate transport maximum to increased secretory load in the rat. Gastroenterol. 73: 129-136, 1977.
3. 14C]diazepam in the streptozotocin diabetic rat. Xenobiotica 14: 751-760, 1984.
4. ARIAS, I. M., CHE, M., GATMAITAN, Z., LEVEILLE, C., NISHIDA, T. AND ST. PEIRRE, M.: The biology of bile canaliculus. Hepatology 17: 318-329, 1993.
5. BADAWY, A. B. AND EVANS, M.: Effects of streptozotocin on the concentrations of rat liver nicotinamide adenine dinucleotides (phosphates) and the activity of tryptophan pyrrolase. Biochem. Soc. Trans. 5: 1314-1316, 1977.
6. BALLATORI, N. AND TRUONG, A. T.: Glutathione as a primary osmotic driving force in hepatic bile formation. Am. J. Physiol. 263: G617-G624, 1992.
7. BARRIENTOS, C., GONZÁLEZ, M., TUÑÒN, M. J., CULEBRAS, J. M. AND GONZALEZ-GALLEGO, J.: Effects of diabetes on disposition and hepatic handling of cefmetazole in rats. Clin. Exp. Pharmacol, Physiol. 20: 399-404, 1993.
8. BASS, N. M. AND WILLIAMS, R. L.: Guide to drug dosage in hepatic disease. Clin. Pharmacokinet. 15: 396, 1988.
9. +-ATPase in the rat hepatocyte. J. Clin. Invest. 62: 1104-1108, 1978.
10. BÜYÜKDEVRIM, A. S.: Islet pathology in streptozotocin-induced auto-immune diabetic mice: New insights into clinical practice. Diab. Metab. 20: 87-94, 1994.
11. CARNOVALE, C. E. AND RODRIGUEZ GARAY, E. A.: Reversible impairment of hepatobiliary function induced by STZ in the rat. Experientia 40: 248-250, 1984.
12. CARNOVALE, C. E., MARINELLI, R. A. AND RODRIGUEZ GARAY, E. A.: Bile flow decrease and altered bile composition in streptozotocin-treated rats. Biochem. Pharmacol. 35: 2625-2628, 1986.
13. CARNOVALE, C. E., MARINELLI, R. A. AND RODRIGUEZ GARAY, E. A.: Toxic effect of streptozotocin on the biliary secretion of nicotinamide-treated rats. Toxicol. Lett. 36: 259-265, 1987.
14. CARNOVALE, C. E., ROMA, M. G., MONTI, J. A. AND RODRIGUEZ-GARAY, E. A.: Studies on the mechanism of bile salt-independent bile flow impairment in streptozotocin-induced hepatotoxicity. Toxicology 68: 207-215, 1991.
15. CASPARY, W. F.: Increase of active transport of conjugated bile salts in streptozotocin-diabetic rat small intestine. Gut 14: 949-955, 1973.
16. FEDORAK, R. N., GERSHON, M. D. AND FIELD, M.: Induction of intestinal glucose carriers in streptozotocin-treated chronically diabetic rats. Gastroenterology 96:37-44, 1989.
17. FRIMMER, M. AND ZIEGLER, K.: The transport of bile acids in liver cells, Biochim. Biophys. Acta 947: 75-99, 1988.
18. GARCIA-MARIN, J. J., VILLANUEVA, G. R. AND ESTELLER, A.: Diabetes-induced cholestasis in the rat: role of bile acid-independent fraction of bile flow. J. Hepatol. 3: S62, 1986.
19. GARCIA-MARIN, J. J., VILLANUEVA, G. R. AND ESTELLER, A.: Diabetes-induced cholestasis in the rat: Possible role of hyperglycemia and hypoinsulinemia. Hepatology 8: 332-340, 1988.
20. GELEHRTER, T. D., SHREVE, P. D. AND DILWORTH, V. M.: Insulin regulation of Na/K pump activity in rat hepatoma cells. Diabetes 33: 428-434, 1984.
21. HOEKMAN, M. F., RIENTJES, J. M., TWISK, J., PLANTA, R. J., PRINCEN, H. M. AND MAGER, W. H.: Transcriptional regulation of the gene encoding cholesterol 7 alpha-hydroxylase in the rat. Gene 130: 217-223, 1993.
22. HOFMANN, A. F.: Bile acids. In The Liver: Biology and Pathobiology, 3rd ed., ed. by I. M. Arias, J. L. Boyer, N. Fausto, W. B. Jakoby, D. A. Schachter and D. A. Shafritz, pp. 677-718, Raven Press, New York, 1994.
23. ICARTE, M. A., PIZARRO, M. AND ACCATINO, L.: Adaptive regulation of hepatic bile salt transport: effects of alloxan diabetes in the rat. Hepatology 14: 671-678, 1991.
24. INOUE, M., KINNE, R., TRAN, T. AND ARIAS, I. M.: Taurocholate transport by rat liver sinusoidal membrane vesicles: Evidence of sodium cotransport. Hepatology 2: 572-579, 1982.
25. +-independent transport system. J. Clin. Invest. 73: 659-663, 1984.
26. +-independent organic transporter. Proc. Natl. Acad. Sci. U.S.A. 91: 133-137, 1994.
27. KING, T. E.: Preparation of succinate dehydrogenase and reconstitution of succinate oxidase. Methods Enzymol. 10: 322-331, 1967.
28. KIRKPATRICK, R. B. AND KRAFT, B. G.: Effect of streptozotocin-induced diabetes on bile acid sulfation in the male rat liver. Am. J. Physiol. 247: G226-G230, 1984.
29. KOLB, H. AND KRÖNCKE, K. D.: Lessons from the low-dose streptozotocin model in mice. Diab. Rev. 1: 116-126, 1993.
30. LOWRY, O. H., ROSENBROUGH, N. J., FARR, A. L. AND RANDALL, R. J.: Protein measurements with Folin phenol reagent. J. Biol. Chem. 193: 265-275, 1951.
31. Lu, A. Y. H., SOMOGYI, A., WEST, S., KUNTZMAN, R. AND CONNEY, A. H.: Pregnenolone-16α-carbonitrile: A new type of inducer of drug-metabolizing enzymes. Arch Biochem. Biophys. 152: 457-462, 1972.
32. MEISTER, A., TATE, S. S. AND GRIFFITH, O. W.: Gamma-glutamyl transpeptidase. Methods Enzymol. 77: 237-253, 1981.
33. MUKHERJEE, B., MUKHERJEE, J. R. AND CHATTERJEE, M.: Lipid peroxidation, glutathione levels and changes in glutathione-related enzyme activities in streptozotocin-induced diabetic rats. Immun. Cell Biol. 72: 109-114, 1994.
34. NAKASHIMA, E., MATSUSHITA, R., TAKEDA, M., NAKANISHI, T. AND ICHIMURA, F.: Comparative pharmacokinetics of cefoperazone and cephradine in untreated streptozotocin diabetic rats. Drug Metab. Disp. 20: 730-735, 1992.
35. OUDE ELFERINK, R. P. J., MEIJER, D. K. F., KUIPERS, F., JANSEN, P. L. M., GROEN, A. K. AND GROOTHUIS, G. M. M.: Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport. Biochim. Biophys. Acta 1241: 215-268, 1995.
36. PARK, I.-S. AND BENDAYAN, M.: Endocrine cells in the rat pancreatic and bile duct system: alterations in diabetes. Pancreas 9: 566-573, 1994.
37. PAUMGARTNER, G., HORAK, W., PROBST, P. AND GRABNER, G.: Effect of phenobarbital on bile flow and bile salt excretion in the rat. Naunyn-Schmiedeberg Arch. Pharmacol. 270: 98-101, 1971.
38. PIKULA, S., HAUDEN, J. B., AWASTHI, S., AWASTHI, Y. C. AND ZIMNIAK, P.: Organic anion-transporting ATPase of rat liver. I. Purification, photoaffmity labeling, and regulation by phosphorylation. J. Biol. Chem. 269: 27566-27573, 1994a.
39. PIKULA, S., HAUDEN, J. B., AWASTHI, S., AWASTHI, Y. C. AND ZIMNIAK, P.: Organic anion-transporting ATPase of rat liver. II. Functional reconstitution of active transport and regulation by phosphorylation. J. Biol. Chem. 269: 27574-27579, 1994b.
40. 2+ transport by rat liver plasma membrane vesicles. J. Biol. Chem. 259: 1382-1385, 1984.
41. SAMSON, M., FEHLMANN, M., DOLAIS-KITABGI, J. AND FREYCHET, P.: Amino acid transport in isolated hepatocytes from streptozotocin-diabetic rats. Diabetes 29: 996-1000, 1980.
42. SCHARSCHMIDT, B. F. AND KEEFFE, E. B.: Isolation of a rat liver membrane fraction of probable canalicular origin: Preparative technique, enzymatic profile, composition, and solute transport. Biochim. Biophys. Acta 646: 369-381, 1981.
43. +-ATPase activity. J. Lab. Clin. Med. 93: 790-799, 1979.
44. SHAFIR, E.: Diabetes in animals. In Diabetes Mellitus: Theory and Practice, ed. by H. Rifkin and D. Porte, pp 302-303, Elsevier, New York, 1990.
45. SIMON, F. R., SUTHERLAND, E. M. AND GONZALEZ, M.: Evidence that increased maximum bile salt secretory capacity is due to increased cholic acid receptors. J. Clin. Invest. 70: 401-411, 1982.
46. SIPPEL, C. J., MCCOLLUM, M. J. AND PERLMUTTER, D. H.: Bile acid transport by the rat liver canalicular bile acid transport/Ecto-ATPase protein is dependent on ATP but not its own Ecto-ATPase activity. J. Biol. Chem. 269: 2820-2826, 1994.
47. +-ATPase. Methods Enzymol. 156: 278-281, 1988.
48. +/taurocholate cotransporting polypeptide in rat liver. Gastroenterology 107: 1781-1787, 1994.
49. TWISK, J., LEHMANN, E. M. AND PRINCEN, H. M. G.: Differential feedback regulation of cholesterol 7-alpha-hydroxylase mRNA and transcriptional activity by rat bile acids in primary monolayer cultures of rat hepatocytes. Biochem. J. 290:685-691, 1993.
50. TWISK, J., DE WIT, E. C. M. AND PRINCEN, H. M. G.: Suppression of sterol 27-hydroxylase mRNA and transcriptional activity by bile acids in cultured rat hepatocytes. Biochem. J. 305: 505-511, 1995a.
51. TWISK, J., HOEKMAN, M. F., LEHMANN, E. M., MEIJER, P., MAGER, W. H. AND PRINCEN, H. M. G.: Insulin suppresses bile acid synthesis in cultured rat hepatocytes by down-regulation of cholesterol 7-α hydroxylase and sterol 27-hydroxylase gene transcription. Hepatology 21: 501-510, 1995b.
52. VILLANUEVA, G. R., HERREROS, M., PEREZ-BARRIOCANAL, F., BOLANOS, J. P., BRAVO, P. AND GARCIA-MARIN, J. J.: Enhancement of bile acid-induced biliary lipid secretion by streptozotocin in rats. J. Lab. Clin. Med. 115: 441-448, 1990.
53. +-ATPase activity in rat liver. J. Clin. Invest. 61: 297-307, 1978.
54. WATKINS, J. B. III AND DYKSTRA, T. P.: Alterations in biliary excretory function by streptozotocin-induced diabetes. Drug Metab. Dispos. 15: 177-183, 1987.
55. WATKINS, J. B. III AND NODA, H.: Biliary excretion of organic anions in diabetic rats. J. Pharmacol. Exp. Ther. 239: 467-473, 1986.
56. WATKINS, J. B. III AND SANDERS, R. A.: Diabetes mellitus-induced alterations of hepatobiliary function. Pharmacol. Rev. 47: 1-23, 1995.
57. WATKINS, J. B. III AND SHERMAN, S. E.: Long-term diabetes alters hepatobiliary clearance of acetaminophen, bilirubin and digoxin. J. Pharmacol. Exp. Ther. 260: 1337-1343, 1992.
58. WEISS, R. B.: Streptozotocin: a review of its pharmacology, efficacy and toxicity. Cancer Treat. Rep. 66: 427-438, 1982.
59. WEY, H. E., YUNKER, R. L., HARRIS, P. AND SUBBIAH, M. T. R.: Effect of streptozotocin-induced diabetes in neonatal rat on bile acid pool changes in adult life: selective sensitivity in females. Biochem. Med. 31: 167-173, 1984.
60. ZIMNIAK, P. AND AWASTHI, Y. C.: ATP-dependent transport systems for organic anions. Hepatology 17: 330-339, 1993.