HIV-type 1 induces specific cytoskeleton alterations in human epithelial cells in culture

European Journal of Dermatology

Volumn 7, Issue 4, 1997, Pages 263-269

  Malorni, Walter ^a   Guiducci, Germana ^b   Pasquinelli, Gianandrea ^b   Rivabene, Roberto ^a   Re, Maria Carla ^c   Ramazzotti, Eric ^c   De Luca, Michele ^e   La Placa, Michelangelo ^d   Cenacchi, Giovanna ^b  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b Inst of Clin Electron Microscopy   (Italy)

^c Institute of Microbiology   (Italy)

^d UNIVERSITY OF BOLOGNA   (Italy)

^e UNIVERSITY OF GENOA   (Italy)

Author keywords

Cytoskeleton; Epithelial cells; HIV 1; Keratinocytes

Indexed keywords

ARTICLE; CELL CULTURE; CELL DAMAGE; CYTOSKELETON; EPITHELIUM CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; ULTRASTRUCTURE;

EID: 0031010236     PISSN: 11671122     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Pantaleo G, Graziosi C, Fauci AS. The immunopathogenesis of human immunodeficiency virus infection. New Engl J Med 1993; 328: 327-35.
2. Owens RJ, Dubay JW, Hunter E, Compans RW. Human immunodeficiency virus envelope protein determines the site of virus release in polarized epithelial cells. Proc Natl Acad Sci USA 1991; 88: 3987-91.
3. Smith KJ, Skelton HG, Angritt P. Histopathologic features of HIV-associated skin diseases. Dermatol Clin 1991; 9: 551-78.
4. Cohen PR. Porphyria cutanea tarda in human immunodeficiency virus-seropositive men: case report and literature review. J Acquir Immun Defic Syndr 1991; 4: 1112-7.
5. Smith KJ, Skelton HG, Yeager J, Angritt P, Frisman D, Wagner KF, Baxter D, James WD, Oster CN. Histopathologic and immunohistochemical findings associated with inflammatory dermatoses in human immunodeficiency virus type 1 disease and their correlation with Walter Reed stage. J Am Acad Dermatol 1993; 28: 174-84.
6. Patrick SL, Wright TC, Fox HE, Ginsberg HS. Human immunodeficiency virus infection of early passage cervical epithelial cultures. Int J Std Aids 1993; 4: 342-5.
7. Heng MC, Heng SY, Allen SG. Co-infection and synergy of human immunodeficiency virus-1 and Herpes simplex virus-1. Lancet 1994; 343: 255-8.
8. Smith KJ, Skelton HG, Yeager J, Ledsky R, McCarthy W, Baxter D, Wagner KF. Cutaneous findings in HIV-1-positive patients: a 42 months prospective study. J Am Acad Dermatol 1994; 31: 746-54.
9. Phillips DM, Bourinbaiar AS. Mechanism of HIV spread from lymphocytes to epithelia. Virology 1992; 186: 261-73.
10. Levy JA. Pathogenesis of human immunodeficiency virus infection. Microbiol Rew 1993; 57: 183-289.
11. Kaplan MH, Sadick NS, McNutt NS, Meltzer M, Sarngadharan G, Pahwa S. Dermatologic findings and manifestations of acquired immunodeficiency syndrome (AIDS). J Acad Dermatol 1987; 16: 485-506.
12. Vogel J, Hinrichs SH, Reynolds RK, Luciw PA, Jay G. The HIV Tat gene induces dermal lesions resembling Kaposi's sarcoma in transgenic mice. Nature 1988; 335: 606-11.
13. Ramazzotti E, Marconi M, Re MC, Girolomoni G, Cenacchi G, Vignoli M, Zambruno G, Furlini G, La Placa M, Giannetti A. In vitro infection of human Langerhans' cells with HIV-1. Immunol 1995; 85: 94-8.
14. McNutt NS, Urmacher C. Las erupciones papuloesacamosas del sindrome de immuno deficiencia adquirida (SIDA). Patologia 1990; 23: 3-9.
15. Buchness MR. Treatment of skin diseases in HIV-infected patients. Dermatol Clin 1995; 13: 231-8.
16. De Luca M, Franzi AT, D'anna F, Zica A, Albanese E, Bondanza S, Cancedda R. Coculture of human keratinocytes and melanocytes: differentiated melanocytes are physiologically organized in the basal layer of the cultured epithelium. Eur J Cell Biol 1988; 46: 176-80.
17. Popovic M, Sarngadharan MG, Read E, Gallo RC. Detection, isolation and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS. Science 1984; 224: 497-500.
18. Lee MH, Sano K, Morales FE, Imagawa DT. Comparable sensitivities for detection of human immunodeficiency virus by sensitive reverse transcriptase and antigen capture enzyme-linked immunosorbent assays. J Clin Microbiol 1988; 26: 371-4.
19. Hahn B, Manzari V, Colombini S, Franchini G, Gallo RC, Wong-Staal F. Common site of integration of HTLV in cells of three patients with mature T-cell leukaemia-lymphoma. Nature 1983; 303: 253-6.
20. Folks TM. Biological and biochemical characterization of a cloned Leu-3-cell surviving infection with the acquired immunodeficiency syndrome retrovirus. J Exp Med 1986; 164: 280-6.
21. Malorni W, Donelli G. Cell death. General features and morphological aspects. Ann New York Acad Sci 1992; 663: 218-33.
22. Yahi N, Baghdiguian S, Moreau H, Fantini J. Galactosyl ceramide (or a closely related molecule) is the receptor for human immunodeficiency virus type f on human colon epithelial HT29 cells. J Virol 1992; 66: 4848-54.
23. Phillips DM. The role of cell-to-cell transmission in HIV infection. AIDS 1994; 8: 719-31.
24. Stingl G, Rappersberger K, Tschachler E, Gartner S, Groh V, Mann DL, Wolff K, Popovic M. Langheran's cells in HIV-1 infection. J Am Acad Dermatol 1990; 22: 1210-7.
25. Zambruno G, Mori L, Marconi A. Detection of HIV-1 in epidermal Langheran's cells of HIV-infected patients using the polymerase chain reaction. J Invest Dermatol 1991; 96: 979-82.
26. Sprecher E, Becker Y. Role of Langheran's cells and other dendritic cells in viral diseases. Arch Virol 1993; 132: 1-28.
27. Nottet H, Janse I, De Graaf L, Bakker L, Visser MR, Verhoef J. Infection of epithelial cell line HEp-2 with human immunodeficiency virus type 1 is CD4 dependent. J Med Virol 1993; 40: 39-43.
28. Zacharopoulos VR, Perotti ME, Phillips DM. Lymphocyte-facilitated infection of epithelia by human T-cell lymphotropic virus type 1. J Virol 1992; 66: 4601-5.
29. Ramarli D, Giri A, Reina S, Poffe O, Cancedda R, Varnier O, Tridente G, De Luca M. HIV-1 spreads from lymphocytes to normal human keratinocytes suitable for autologous and allogenic transplantation. J Invest Dermatol 1995; 105: 644-7.
30. Legrand-Poels S, Vaira D, Pincemail J, Van Der Vorst A, Piette J. Activation of human immnodeficiency virus type 1 by oxidative stress. AIDS Res Hum Retroviruses 1990; 6: 1389-97.
31. Westendorp MO, Shatrov VA, Schulze-Osthoff K, Frank R, Kraft M, Los M, Krammer PH, Droge W, Lehmann V. HIV-1 Tat potentiates TNF-induced NF-kappa B activation and cytotoxicity by altering the cellular redox state. EMBO J 1995; 14: 546-54.
32. Luftig RB, Lupo LD. Viral interactions with the host-cell cytoskeleton: the role of retroviral proteases. Trends Microbiol 1994; 2: 178-82.
33. Honer B, Shoeman RL, Traub P. Degradation of cytoskeletal proteins by the human immunodeficiency virus type 1 protease. Cell Biol Int Rep 1992; 16: 603-12.
34. Honer B, Shoeman RL, Traub P. Human immunodeficiency virus type 1 protease microinjected into cultured human skin fibroblasts cleaves vimentin and affects cytoskeletal and nuclear architecture. J Cell Sci 1991; 100: 799-807.
35. Shoeman RL, Honer B, Stoller TJ, Kesselmeier C, Miedel MC, Traub P, Graves MC. Human immunodeficiency virus type 1 protease cleaves the intermediate filament proteins vimentin, desmin, and glial fibrillary acidic protein. Proc Natl Acad Sci USA 1990; 87: 6336-40.
36. Ruoslahti E, Reed JC. Anchorage dependence, integrins, and apoptosis. Cell 1994; 77: 477-8.
37. Pearce-Pratt R, Malamud D, Phillips DM. Role of the cytoskeleton in cell-to-cell transmission of human immunodeficiency virus. J Virol 1994; 68: 2898-905.
38. Compans RW. Virus entry and release in polarized epithelial cells. Curr Top Microbiol Immunol 1995; 202: 209-19.
39. +) progenitors cells in AIDS patients. J Infect Dis 1992; 166: 710-6.
40. Beons DJ, Hahn BH, Bubien JK, Ghosh SK, Mashburn NA, Chaikin MA, Shaw GM, Benveniste ET. Envelope glycoprotein gp120 of human immunodeficiency virus type 1 alters ion transport in astrocytes: implications for AIDS dementia complex. Proc Natl Acad Sci USA 1994; 91: 494-8.