Cross-linking of integrins induces tyrosine phosphorylation of the proto-oncogene product Vav and the protein tyrosine kinase Syk in human factor-dependent myeloid cells

Cell Growth and Differentiation

Volumn 8, Issue 6, 1997, Pages 721-729

  Gotoh, Akihiko ^a   Takahira, Hiroyuki ^a   Geahlen, Robert L ^b   Broxmeyer, Hal E ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; FIBRONECTIN RECEPTOR; GENE PRODUCT; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GROWTH FACTOR; INTEGRIN; INTERLEUKIN 3; PHOSPHOTYROSINE; PROTEIN TYROSINE KINASE; STEEL FACTOR; TYROSINE;

ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN PHOSPHORYLATION; PROTO ONCOGENE; SIGNAL TRANSDUCTION;

BLOTTING, WESTERN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL ADHESION; CELL CYCLE PROTEINS; CELL LINE; CYTOKINES; ENZYME PRECURSORS; GLYCOGEN SYNTHASE KINASE 3; GROWTH SUBSTANCES; HEMATOPOIETIC STEM CELLS; HUMANS; INTEGRINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-VAV; RECEPTORS, FIBRONECTIN; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; STEM CELL FACTOR; TYROSINE;

EID: 0031010040     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Gordon, M. Y. Extracellular matrix of the bone marrow microenvironment. Br. J. Haematol., 70: 1-4, 1988.
2. Pytela, R., Pierschacher, M. D., and Ruoslahti, E. Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor. Cell, 40: 191-198, 1985.
3. Simmons, P. J., Zannettino, A., Gronthos, A., and Leavesley, D. Potential adhesion mechanisms for localization of haematopoietic progenitors to bone marrow stroma. Leuk. & Lymphoma, 12: 353-363, 1994.
4. Wayner, E. A., Garcia-Pardo, A., Humphries, M. J., MacDonald, J. A., and Carter, W. G. Identification and characterization of the T lymphocyte adhesion receptor for an alternative cell attachment domain (CS-1) in plasma fibronectin. J. Cell Biol., 109: 1321-1330, 1989.
5. Guan, J-L., and Hynes, R. O. Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor α4β1. Cell, 60: 53-61, 1990.
6. Mould, A. P., Komoriya, A., Yamada, K. M., and Humphries, M. J. The CS5 peptide is a second site in the IIICS region of fibronectin recognized by the integrin α4β1: inhibition of α4β1 function by RGD peptide homologues. J. Biol. Chem., 266: 3579-3585, 1991.
7. Verfaillie, C. M., McCarthy, J. B., and McGlave, P. B. Differentiation of primitive human multipotent hematopoietic progenitors into single lineage clonogenic progenitors is accompanied by alteration in their interaction with fibronectin. J. Exp. Med., 174: 693-703, 1991.
8. Williams, D. A., Rios, M., Stephens, C., and Patel, V. P. Fibronectin and VLA-4 in haematopietic stem cell-microenvironment interactions. Nature (Lond.), 352: 438-441, 1991.
9. Hynes, R. O. Integrins: versatility, modulation and signaling in cell adhesion. Cell, 69: 11-25, 1992.
10. Hardy, C. L., and Minguell, J. J. Modulation of the adhesion of hemopoietic progenitor cells to the RGD site of fibronectin by interleukin-3. J. Cell. Physiol., 164: 315-323, 1995.
11. Levesque, J-P., Leavesley, D. I., Niutta, S., Vadas, M., and Simmons, P. J. Cytokines increase human hemopoietic cell adhesiveness by activation of very late antigen (VLA)-4 and VLA-5 integrins. J. Exp. Med., 181: 1805-1815, 1995.
12. Clark, E. A., and Brugge, J. S. Integrins and signal transduction pathways: the road taken. Science (Washington DC), 268: 233-239, 1995.
13. Broxmeyer, H. E, Maze, R., Miyazawa, K., Carow, C., Hendrie, P. C., Cooper, S., Hangoc, G., Vadhan-Raj, S., and Lu, L. The kit receptor and its ligand Steel factor as regulators of hemopoiesis. Cancer Cells, 3: 480-487, 1991.
14. Miyazawa, K, Hendrie, P. C., Mantel, C., Wood, K., Ashman, L. K., and Broxmeyer, H. E. Comparative analysis of signaling pathways between mast cell growth factor (c-kit ligand) and granulocyte-macrophage colony stimulating factor in a human factor-dependent myeloid cell line involves phosphorylation of Raf-1, GTPase-activating protein and mitogen-activated protein kinase. Exp. Hematol., 19: 1110-1123, 1991.
15. Miyazawa, K., Williams, D. A., Gotoh, A., Nishimaki, J., and Broxmeyer, H. E. Membrane-bound Steel factor induces more persistent tyrosine kinase activation and longer life span of c-kit gene-encoded protein than its soluble form. Blood, 85: 641-649, 1995.
16. Aronica, S. M., Mantel, C., Gonin, R., Marshall, M. S., Sarris, A., Cooper, S., Hague, N., Zhang, X-F., and Broxmeyer, H. E. Interferon-inducible protein 10 and macrophage inflammatory protein-1α inhibit growth factor stimulation of Raf-1 kinase activity and protein synthesis in a human growth factor-dependent hematopoietic cell line. J. Biol. Chem., 270: 21998-22007, 1995.
17. + cells to fibronectin in an activation-dependent way. Blood, 81: 344-351, 1993.
18. high stem cells to bone marrow stroma. J. Clin. Invest., 90: 358-367, 1992.
19. Liesveld, J. L., Winslow, J. M., Frediani, K. E., Ryan, D. H., and Abboud, C. N. Expression of integrins and examination of their adhesive function in normal and leukemic hematopoietic cells. Blood, 81: 112-121, 1993.
20. vav, in human hemopoietic cells. J. Biol. Chem., 267: 18021-18025, 1992.
21. Geahlen, R. L., and Burg, D. L. The role of Syk in cell signaling. Adv. Exp. Med. Biol., 365: 103-109, 1994.
22. Cohen, G. B., Ren, R., and Baltimore, D. Modular binding domains in signal transduction proteins. Cell, 80: 237-248, 1995.
23. Hu, P., Margolis, B., Schlessinger, J. Vav: a potential link between tyrosine kinases and ras-like GTPases in hematopoietic cell signaling. BioEssays, 15: 179-183, 1993.
24. Gulbins, E., Langlet, C., Baier, G., Bonnefoy-Berard, N., Herbert, E., Altman, A., and Coggeshall, K. M. Tyrosine phosphorylation and activation of Vav GTP/GDP exchange activity in antigen receptor-triggered B cells. J. Immunol., 152: 2123-2129, 1994.
25. Gulbins, E., Coggeshall, K. M., Baier, G., Telford, D., Langlet, C., Baier-Bitterlich, G., Bonnefoy-Berard, N., Burn, P., Wittinghofer, A., and Altman, A. Direct stimulation of Vav guanine nucleotide exchange activity for Ras by phorbol esters and diglycerides. Mol. Cell. Biol., 14: 4749-4758, 1994.
26. Bustelo, X. R., Suen, K-L., Leftheris, K., Meyers, C. A., and Barbacid, M. Vav cooperates with Ras to transform rodent fibroblasts but is not a Ras GDP/GTP exchange factor. Oncogene, 9: 2405-2413, 1994.
27. Khosravi-Far, R., Chrzanowska-Wodnicka, M., Solski, P. A., Eva, A., Burridge, K., and Der, C. J. Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras. Mol. Cell. Biol., 14: 6848-6857, 1994.
28. Cichowski, K., Brugge, J. S., and Brass, L. F. Thrombin receptor activation and integrin engagement stimulate tyrosine phosphorylation of the proto-oncogene product, p95vav, in platelets. J. Biol. Chem., 271: 7544-7550, 1996.
29. Chen, Q., Kinch, M. S., Lin, T. H., Burridge, K., and Juliano, R. L. Integrin-mediated cell adhesion activates mitogen-activated protein kinases. J. Biol. Chem., 269: 26602-26605, 1994.
30. erk-2. J. Biol. Chem., 270: 269-273, 1995.
31. Lin, T. H., Rosales, C., Mondal, K., Bolen, J. B., Haskill, S., and Juliano, R. L. Integrin-mediated tyrosine phosphorylation and cytokine message induction in monocytic cells. J. Biol. Chem., 270: 16189-16197, 1995.
32. Corey, S. J., Burkhardt, A. L., Bolen, J. B., Geahlen, R. L., Tkatch, L. S., and Tweardy, D. J. Granulocyte colony-stimulating factor receptor signaling involves the formation of a three-component complex with Lyn and Syk protein-tyrosine kinases. Proc. Natl. Acad. Sci. USA, 91: 4683-4687, 1994.
33. Avanzi, G. C., Lista, P., Giovinazzo, B., Miniero, R., Saglio, G., Benetton, G., Coda, R., Cattoretti, G., and Pegoraro, L. Selective growth response to IL-3 of a human leukemic cell line with megakaryoblastic features. Br. J. Haematol., 69: 359-366, 1988.
34. Hendrie, P. C., Miyazawa, K., Young, Y-C., Langefeld, C. D., and Broxmeyer, H. E. Mast cell growth factor (c-kit ligand) enhances cytokine stimulation of proliferation of the human factor-dependent cell line, M07e. Exp. Hematol., 19: 1031-1037, 1991.
35. Burg, D. L., Furlong, M. T., Harrison, M. L., and Geahlen, R. L. Interactions of Lyn with the antigen receptor during B cell activation. J. Biol. Chem., 269: 28136-28142, 1994.
36. Gotoh, A., Takahira, H., Mantel, C., Litz-Jackson, S., and Boswell, H. S., and Broxmeyer, H. E. Steel factor induces serine phosphorylation of Stat3 in human growth factor-dependent myeloid cell lines. Blood, 88: 138-145, 1996.
37. Peters, J. O., Furlong, M. T., Asai, D. J., Harrison, M. L., and Geahlen, R. L. Syk, activated by cross-linking the B-cell antigen receptor, localizes to the cytosol where it interacts with and phosphorylates α-tubulin on tyrosine. J. Biol. Chem., 271: 4755-4762, 1996.
38. Miyazawa, K., Hendrie, P. C., Kim, Y-J, Mantel, C., Yang, Y-C., Kwon, B. S., and Broxmeyer, H. E. Recombinant human interleukin-9 induces protein tyrosine phosphorylation and synergizes with Steel factor to stimulate proliferation of the human factor-dependent cell line, M07e. Blood, 80: 1685-1692, 1992.