Capillary electrophoresis with laser-induced fluorescence detection, an adequate alternative to high-performance liquid chromatography, for the determination of ciprofloxacin and its metabolite desethyleneciprofloxacin in human plasma

Journal of Chromatography B: Biomedical Applications

Volumn 692, Issue 2, 1997, Pages 453-459

  Bannefeld, K H ^a   Stass, H ^b   Blaschke, G ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b Institute of Clinical Pharmacology   (Germany)

Author keywords

Ciprofloxacin; Desethyleneciprofloxacin

Indexed keywords

CIPROFLOXACIN; DRUG METABOLITE;

ACCURACY; ADULT; ARTICLE; CALIBRATION; CAPILLARY ELECTROPHORESIS; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; INTERMETHOD COMPARISON; LASER; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; TECHNIQUE;

ANTI-INFECTIVE AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIPROFLOXACIN; ELECTROPHORESIS, CAPILLARY; FLUOROQUINOLONES; HUMANS; LASERS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, FLUORESCENCE;

EID: 0031009832     PISSN: 15726495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(96)00539-7     Document Type: Article

References (12)

1. N.W. Smith and M.B. Evans, J. Pharm. Biomed. Anal., 12 (1994) 753.
2. K.D. Altria, J. Chromatogr., 646 (1993) 245.
3. S.R. Rabel and J.F. Stobaugh, Pharm. Res., 10 (1993) 171.
4. Z. Deyl, F. Tagliaro and I. Miksik, J. Chromatogr. B, 656 (1994) 3.
5. H. Wätzig and C. Dette, Pharmazie, 49 (1994) 83.
6. T.T. Lee, S.J. Lillard, J. Sheri and E.S. Yeung, Electroc phoresis, 14 (1993) 429.
7. N.J. Reinhoud, U.R. Tjaden, H. Irth and J. van der Greef, J. Chromatogr., 574 (1992) 327.
8. G. Hempel and G. Blaschke, J. Chromatogr. B, 675 (1996) 131.
9. G. Hempel and G. Blaschke, J. Chromatogr. B, 675 (1996) 139.
10. F. Jehl, C. Gallion, J. Debs, J.M. Brogard, H. Monteil and R. Minck, J. Chromatogr., 339 (1985) 347.
11. A.C. Mehta, F. Hart-Davies and E.A. Kay, J. Clin. Pharm. Ther., 17 (1992) 117.
12. H.G. Schaefer, H. Stass, J. Wedgwood, B. Hampel, C. Fischer, J. Kuhlmann and U.B. Schaad, Antimicrob. Agents Chemother., 40 (1996) 29.